Sebastian Kalamajski on genetic aspects of adiposity-related traits; Yuval Dor on DNA methylation–based assessment of pancreas and islet cells; and Carmella Evans-Molina on the role of calcium in regulating insulin secretion.
Release Date: 04/02/2024
Wilson & Moore on B Lymphocytes and eroding islet tolerance in type 1 diabetes, Mittendorfer on the effects of marked weight loss on postprandial glucose disposal in type 2 diabetes, plus “Sweet Talk” with Sir Stephen O’Rahilly
DiabetesBio
Welcome to the February 2026 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the February 2026 issue of Diabetes. 6:10 To discuss this issue’s Paper of the Month, our hosts are joined by authors , PhD and , MD, PhD, both of Vanderbilt University. Their article, “B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes,” is available for free at ....
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Masaya Oshima on the effects of killing human β-cells by CD8+ T cells and “Sweet Talk” with Sarah Stanely on the neural regulation of blood glucose in acute stress
DiabetesBio
Welcome to the January 2026 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the January 2026 issue of Diabetes. 17:40 After sharing their predictions for the new year, our hosts are joined by , PhD, a contract researcher at Institut Cochin in Paris, France. He is the lead author on the January Paper of the Month, “Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory...
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Bergman on altering lipid localization and adipose tissue cellular composition through weight loss and exercise, Walters, Castro-Gutierrez, Mukherjee & Russ on HLA immune presentation on Human β-Cells, metabolic “Sweet Talk” with Banks, Holman, & Lan
DiabetesBio
Welcome to the December 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the December 2025 issue of Diabetes. 13:10 After discussing their favorite interviews of the past two years, our hosts are joined by , PhD, a professor in the Division of Endocrinology, Metabolism, and Diabetes at the University of Colorado Anschutz Medical Campus. He is the corresponding author of “Combined...
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Kaylia Reynolds and Nora Franceschini on diabetes genetic clusters, Stephanie Holm & Christoffer Clemmensen on sustained weight loss with LEAP2 & Semaglutide, plus “Sweet Talk” with Banting Medal recipient Jens Juul Holst
DiabetesBio
Welcome to the November 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the November 2025 issue of Diabetes. 6:00 In the first segment, our hosts are joined by , MS and , MD, MPH, FAHA, both of the Department of Epidemiology at the Gillings School of Global Public Health at the University of North Carolina. Their paper, “Diabetes Genetic Clusters and Clinical Outcomes in...
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Cacciottoloon on glucagon receptor deficiency & early-onset hepatic steatosis, “Sweet Talk” on childhood obesity with Nadeau & Cartwright, plus a special segment: speaking to kids directly with their questions about diabetes and obesity
DiabetesBio
Welcome to the October 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the October 2025 issue of Diabetes. 5:50 In the first segment, our hosts are joined by , PhD, a Chain Florey TTI Fellow in the MRC Laboratory of Medical Sciences at Imperial College London. She is the first author of the article “Glucagon Receptor Deficiency Causes Early-Onset Hepatic Steatosis,” available...
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Quarta on GLP-1-mediated targeting of inflammation and obesogenic memory in mice, Hsueh on dulaglutide and hepatic steatosis in obesity via a weight-independent mechanism, & “Sweet Talk” with Pathway to Stop Diabetes Award recipient Alexander Nectow
DiabetesBio
Welcome to the September 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the September 2025 issue of Diabetes. 5:25 In the first segment, our hosts are joined by , PhD, a principal investigator at INSERM (National Institute of Health and Medical Research) and a group leader at the Bordeaux Neurocampus at the University of Bordeaux in France. He is the co-corresponding author of...
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Special Edition: Highlights from the ADA’s 2025 Scientific Sessions
DiabetesBio
In this special crossover episode, recorded live at the American Diabetes Association’s 85th Scientific Sessions in Chicago, the hosts of ADA’s professional podcasts—Diabetes Core Update, Diabetes Care “On Air”, and DiabetesBio—come together to discuss key highlights and groundbreaking research presented at the 2025 meeting. They share expert insights across the bench-to-bedside spectrum, including basic science, clinical research, and the latest in diabetes care and education. Tune in for thoughtful reflections on what this year’s findings mean for clinical...
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A special extended “Sweet Talk” episode on the debate between GIP receptor agonism and GIP receptor antagonism, with Daniel Drucker, OC, MD, FRCPC, FRSC, FRS, and Jonathan Campbell, PhD.
DiabetesBio
Welcome to the August 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the August 2025 issue of Diabetes. 6:55 For this month’s episode, a special extended edition of “Sweet Talk,” exploring the debate about whether GIP receptor agonism or GIP receptor antagonism holds the most promise for therapeutic strategies. First, our hosts are joined by , OC, MD, FRCPC, FRSC, FRS, recipient...
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Suganami & Tanaka on regulation of adipose tissue fibrosis, Watanabe on genetic variations in GCKR & PNPLA3 regulating metabolic balance across the liver, “Sweet Talk” with the 2025 Albert Renold Distinguished Career Award recipient Barbara B. Khan
DiabetesBio
Welcome to the July 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the July 2025 issue of Diabetes. 6:50 In the first interview segment, our hosts discuss July’s Paper of the Month, titled “Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis.” They’re joined by corresponding authors Dr. , professor in the Department...
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Okamoto & Bao on hepatic PKA mediating liver and pancreatic α-cell cross talk, Kowalski on the effect of small blood glucose increases on endogenous glucose production, Sweet Talk with the 2025 Outstanding Scientific Achievement Award recipient Kajimura
DiabetesBio
Haruka Okamoto & Kehan Bao on hepatic PKA mediating liver and pancreatic α-cell cross talk, Greg Kowalski on the effect of small blood glucose increases on endogenous glucose production, and “Sweet Talk” with the 2025 Outstanding Scientific Achievement Award recipient Shingo Kajimura. Welcome to the June 2025 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2025 issue of...
info_outlineWelcome to the April 2024 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes. In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the April 2024 issue of Diabetes.
2:55: To kick things off, Darleen and Kirk are joined by Dr. Sebastian Kalamajski (Lund University), senior author of “Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function.” This article can be freely accessed at https://doi.org/10.2337/db23-0531.
15:16: Darleen and Kirk chat with Dr. Yuval Dor (The Hebrew University of Jerusalem), senior author of “DNA Methylation–Based Assessment of Cell Composition in Human Pancreas and Islets.” This study can be freely accessed at https://doi.org/10.2337/db23-0704.
42:50: Darleen introduces a very special guest for this month’s Sweet Talk, Dr. Carmella Evans-Molina. She is the director of the Center for Diabetes and Metabolic Diseases at Indiana University School of Medicine, and she was awarded the 2023 Outstanding Scientific Achievement Award by the American Diabetes Association. Darleen and Kevin raise many topics in this conversation with Dr. Evans-Molina, from her focus on the role of calcium in regulating insulin secretion to the importance of serendipity and collaboration in scientific research to her recent hobby of learning to play the piano.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes. Thank you for listening, and don’t forget to smash that “follow” button!