AI is Rewriting Marketing - Ready or Not with Talisha Padgett (Microsoft)| The AI CEO Podcast

The AI CEO Podcast is a show for CEOs, founders, and business leaders navigating the biggest technology shift of our lifetime. Each episode explores how artificial intelligence is reshaping leadership, business strategy, marketing, and growth—translating complex AI concepts into practical insights leaders can use to make smarter decisions and stay competitive.

AI is no longer optional—it’s redefining how companies operate, compete, and lead. In this episode of The AI CEO Podcast, Talisha Padgett breaks down why successful AI adoption starts with people, process, and data, how leaders should view AI as a strategic partner, and what CEOs must do now to build resilient, human-centered organizations in an AI-driven world.

In this episode, you’ll learn:

-Why “people, process, and technology” must evolve together
-How CEOs should think about AI strategy—not just tools
-Real-world marketing and AI use cases that save time and money
-Why data quality is the real competitive moat
-How to keep humans in the loop while scaling with AI

Timestamps:

00:00 – How CEOs should think about AI and change
01:15 – Podcast and guest introduction (Talisha Padgett, Microsoft)
03:00 – People, process, and technology in AI transformation
06:30 – Human Loop Consulting and change management
09:00 – Fear, jobs, and keeping humans in the loop
12:00 – Learning AI as a non-technical leader
18:00 – Why AI pilots fail and how to succeed
25:00 – Microsoft Copilot and practical AI adoption
33:00 – Personalization at scale and real-world examples
39:00 – AI’s impact on marketing roles
46:00 – Privacy, regulation, and responsible AI
57:00 – Deepfakes, security, and data protection
59:00 – Unlocking value from existing business data
01:02:00 – AI strategy for startup CEOs
01:06:00 – Early-stage growth and positioning
01:10:00 – AI maturity, leadership responsibility, optimism
01:15:00 – Final reflections on AI, humans, and the future
01:19:00 – Closing thoughts and wrap-up

About Talisha Padgett

Talisha Padgett is the General Manager of Marketing Technology & AI at Microsoft and the Founder of Human Loop Consulting, where she operates at the intersection of marketing transformation, artificial intelligence, and human-centered change management.
With over two decades of experience leading digital and marketing transformation across global brands—including Microsoft, Under Armour, Marriott International, and Comcast—Talisha brings a rare blend of enterprise-scale execution and strategic clarity. Her work focuses on helping organizations modernize marketing operations by aligning people, process, data, and technology to real business outcomes.

LinkedIn: https://www.linkedin.com/in/talishapadgett/

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About Seema Alexander

Seema Alexander is the Founder of Disruptive AI, Co-Chair of DC Startup & Tech Week, and host of The AI CEO Podcast. She guides CEOs, founders, and business leaders through AI adoption, organizational transformation, and the future of business. She is also an international keynote speaker on AI and business for global audiences.

Her upcoming AI CEO School and AI Business Conference will provide strategic education, tools, and frameworks for non-technical CEOs and founders navigating the AI era.

IG: https://www.instagram.com/seemaalexander/
LinkedIn: https://www.linkedin.com/in/seemaalexander/
Disruptive AI: www.getdisruptive.ai

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