S1E4 Why Diet and Exercise Stop Working After 40 — And How to Reignite Your Metabolism
Release Date: 01/14/2026
40s Forward
In this episode of the 40s Forward Podcast, Dr. Betsy Greenleaf takes a deep, science-backed, and refreshingly honest look at why so many adults over 40 feel cold all the time. What is often dismissed as “just aging” is actually a powerful physiological signal related to metabolism, hormones, muscle mass, mitochondrial health, and nervous system balance. This episode explains why cold intolerance increases with age, how it connects to energy production at the cellular level, and what practical lifestyle medicine strategies can help restore warmth, resilience, and vitality. Shocking Truths...
info_outline40s Forward
In this episode of 40s Forward, Dr. Betsy Greenleaf addresses the widespread belief that hormones are dangerous—a misconception rooted in the Women’s Health Initiative (WHI) study published in 2001. Dr. Greenleaf explains what the WHI actually studied, why its findings were misunderstood, and how fear-based messaging has affected hormone care for decades. This episode explores the science of hormone metabolism, including estrogen pathways and why synthetic, non-bioidentical hormones used in the WHI preferentially metabolize down pathways that can create toxic...
info_outline40s Forward
Is Diabetes Reversible? Dr. Beverly Yates Explains What Most Doctors Miss What if diabetes isn’t a life sentence—but a metabolic wake-up call? In this powerful episode of the 40s Forward Podcast, Dr. Betsy Greenleaf sits down with Dr. Beverly Yates, a nationally respected expert in metabolic health, to unpack one of the most misunderstood questions in modern medicine: Is diabetes reversible? Together, they explore why conventional approaches so often fail—especially in midlife—and what’s frequently missed in standard care, particularly for women navigating hormonal shifts, insulin...
info_outline40s Forward
If calorie counting, cardio, and “doing more” used to work—but don’t anymore—this episode explains why. In this episode of the 40s Forward Podcast, Dr. Betsy Greenleaf breaks down the real biology of midlife metabolism and why traditional weight-loss advice fails after 40. Your metabolism isn’t broken—it has changed. And fighting it only makes things worse. After 40, muscle loss, hormonal shifts, insulin resistance, elevated cortisol, poor sleep, and inflammation all change how your body processes food and stores fat. This episode explains what’s actually happening—and how to...
info_outline40s Forward
If you’ve tried hormone therapy and still don’t feel like yourself… If your labs are “normal” but your symptoms aren’t… If you’re confused, frustrated, or afraid of hormones… This episode will change how you understand your body. In this episode of the 40s Forward Podcast, Dr. Betsy Greenleaf explains why hormone therapy fails so many people — and why the problem is not your hormones, but the outdated, incomplete way hormones are treated. Hormones are chemical messengers that influence energy, metabolism, mood, sleep, libido, cognition, confidence, and aging. Treating...
info_outline40s Forward
Have you ever looked in the mirror after 40 and thought, “Why isn’t anything working the way it used to?” You’re eating well. You’re exercising. You’re doing “all the right things.” And yet your energy is lower, your sleep is off, your weight is harder to manage, your stress feels heavier, and your libido may not feel like you anymore. In this episode of 40s Forward, Dr. Betsy Greenleaf breaks down why everything changes after 40 — and more importantly, how to get it back. This is not about aging, willpower, or discipline. It’s about biology, hormones, metabolism,...
info_outline40s Forward
The holidays are supposed to be joyful — but for many people over 40, they can feel overwhelming, exhausting, and quietly stressful. In this special episode of 40s Forward, Dr. Betsy Greenleaf breaks down why the holidays hit harder after 40 and how to protect your energy, hormones, metabolism, and emotional well-being without guilt or perfectionism. You’ll learn why your body responds differently to stress, sugar, alcohol, late nights, and family dynamics in midlife — and how to navigate the season with grace, strategy, and self-leadership instead of burnout. This episode is not about...
info_outlineIf calorie counting, cardio, and “doing more” used to work—but don’t anymore—this episode explains why.
In this episode of the 40s Forward Podcast, Dr. Betsy Greenleaf breaks down the real biology of midlife metabolism and why traditional weight-loss advice fails after 40. Your metabolism isn’t broken—it has changed. And fighting it only makes things worse.
After 40, muscle loss, hormonal shifts, insulin resistance, elevated cortisol, poor sleep, and inflammation all change how your body processes food and stores fat. This episode explains what’s actually happening—and how to reset your metabolism using science-backed strategies that work with midlife physiology, not against it.
In This Episode, You’ll Learn:
• Why metabolism changes after 40
• The critical role of muscle in fat loss and energy
• Why calories-in/calories-out fails in midlife
• How stress and cortisol drive fat storage
• The powerful connection between sleep and metabolism
• The 5 biggest metabolic saboteurs after 40
• Why eating less and doing more cardio backfires
The 40s Forward Metabolism Reset™
Dr. Greenleaf introduces a smarter approach to midlife metabolism that focuses on:
• Protein-first nutrition
• Muscle-building as medicine
• Cortisol-aware exercise
• Hormone optimization
• Gut health and inflammation repair
Memorable Takeaways:
“Your metabolism isn’t broken—it has changed.”
“Hormones decide what happens to calories, not math.”
“Muscle is the metabolic engine.”
“Midlife bodies don’t need less—they need smarter.”
This episode is essential for anyone navigating weight gain, low energy, stubborn fat, or metabolic frustration after 40.
Resources & Next Steps:
• Learn more about hormone, metabolism, and vitality optimization at PauseInstitute.com
• Explore pelvic and sexual wellness products at the Pelvic Floor Store
• Discover the Muse Headband for stress and nervous system support
• Download Insight Timer and search for DrBetsyGreenleaf
🎧 Subscribe to the 40s Forward Podcast for weekly conversations on hormones, metabolism, energy, and thriving after 40.
Because life doesn’t decline after 40 — it evolves.