Episode 112: Human Growth Hormone (HGH) – Does it work? – Dr. Brad Anawalt / Dr. Andy Hoofnagle
Release Date: 01/09/2024
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Human Growth Hormone (HGH) – Does it work? – Dr. Brad Anawalt / Dr. Andy Hoofnagle
The ALL ME Podcast is working hard to provide you with information from the World’s leading experts when it comes to all things Appearance and Performance Enhancing Substance related. Throughout the year we ask our listeners to send us topics they’d like to learn more about. Recently we’ve been getting asked a lot about Human Growth Hormone (HGH or GH). Not only have people written in requesting more information on GH, we have had questions from students following our programs. In order for us to have the best understanding of these drugs we have gone out and found multiple experts to interview on this topic. In this podcast you’re going to hear from two brilliant and highly respected Doctors and Researchers in their field.

Dr. Brad Anawalt
Bradley Anawalt, M.D., is UW Medical Center’s chief of Medicine and a board certified physician at the Endocrine and Diabetes Care Center at UW Medical Center – Roosevelt and Fred Hutchinson Cancer Center. He is also vice chair of UW's Department of Medicine and a UW professor of General Internal Medicine. He has been selected on local and national lists of "Best Doctors."
Dr. Anawalt is an hormone specialist whose clinical interests include thyroid disorders, osteoporosis, male infertility, low testosterone and other hormonal abnormalities. He enjoys answering patients' questions and addressing their concerns.
Dr. Anawalt earned his M.D. at UC Davis. His primary research interests are focused on the effects of testosterone in men. He has published widely on this topic. He has served in leadership roles in the Endocrine Society and acts as a consultant for the United States Anti-Doping Agency.
Dr. Andy Hoofnagle
Andy Hoofnagle, M.D., Ph.D., is a board certified pathologist for Laboratory Medicine at UW Medical Center, head of Clinical Chemistry and a UW professor of Laboratory Medicine.
Dr. Hoofnagle's lab uses mass spectrometry in the care of patients. In addition, they are currently investigating the role of high density lipoproteins in protecting patients with chronic kidney disease from atherosclerosis. It is his main goal to provide the most accurate testing for every patient in the UW Medicine healthcare system. He feels his talented medical laboratory scientists are in a league of their own.
Dr. Hoofnagle earned his M.D. and Ph.D. from the University of Colorado. His clinical and research interests include clinical chemistry, mass spectrometry, proteomics, metabolomics, vitamin D and high density lipoproteins.
Both of these gentlemen are going to take the topic of Human Growth Hormone and break it down to where you’re able to understand what it is, why is prescribed and how it works. There is a lot of misinformation out there on this topic and these guys do a great job of providing great information as well as debunking many of the HGH myths.
Disclaimer
The content in this podcast represents the opinion and knowledge of our guests. This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing “standard of care” in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast The content should not be taken as medical advice and is for information purposes only. Should you have any medical questions please consult your healthcare professional.
Resources and Links:
Websites: https://www.uwmedicine.org/bios/bradley-anawalt#about-tab
What are the risks of HGH treatment?
HGH treatment might cause a number of side effects for healthy adults, including:
· Carpal tunnel syndrome
· Increased insulin resistance
· Type 2 diabetes
· Swelling in the arms and legs (edema)
· Joint and muscle pain
· For men, enlargement of breast tissue (gynecomastia)
· Increased risk of certain cancers
Clinical studies of HGH treatment in healthy older adults have been relatively small and short in duration, so there's little to no information about the long-term effects of HGH treatment.
Example of Acromegaly
According to the Mayo Clinic: Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood.
When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn't occur. Instead, the increase in bone size is limited to the bones of your hands, feet and face, and is called acromegaly.

Because acromegaly is uncommon and the physical changes occur slowly over many years, the condition sometimes takes a long time to recognize. Untreated, high levels of growth hormone can affect other parts of the body, in addition to your bones. This can lead to serious — sometimes even life-threatening — health problems. But treatment can reduce your risk of complications and significantly improve your symptoms, including the enlargement of your features.
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