Dangers of Muscle Loss - Episode 2763

Episode 2763- Vinnie Tortorich and Anna Vocino discuss the adverse effects of GLP-1s, the dangers of muscle loss, and whether more fiber is necessary.

https://vinnietortorich.com/2026/02/dangers-of-muscle-loss-episode-2763

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Dangers of Muscle Loss

• Semiglutide update: hate to say "I told ya so..." 4:00)
  • They discuss perpetual motion. (8:00)
  • This relates to GLP-1 in the fact that there is nothing you can do that doesn’t cause a consequence somewhere else. (11:30)
• Vinnie discusses dealing with his second bout of cancer a couple of years ago.
  • He is determined to be as active and healthy as possible.
  • Eating strict NSNG seems to have helped him fight cancer more than if he had not been eating clean. (12:00)
• If you lose weight the old-fashioned way through proper eating, about 20-25% of your weight loss will be muscle. (16:00)
  • However, that can be offset with exercise, particularly strength training.
• With GLP-1, a person will lose at least 40% of their muscle mass. (17:00)
  • This matters because a lack of muscle contributes to all-cause mortality, and you can die sooner.
• Sarcopenia (natural muscle loss) occurs with age, typically starting around age 35, but it can be significantly slowed with strength training. (18:00)
• The number one drug Vinnie used to get asked about was statins, but now it’s about GLP-1s. (21:00)
• If a person is losing a lot of muscle on GLP-1s, you can bet it’s affecting their heart, because the heart is muscle. (25:00)
• Anna shares some info she’s heard recently regarding Dr. Ben Bikman. (27:30)

Some Thoughts About Fiber

• There is also debate about fiber. (36:00)
  
  • They discuss myths about fiber and whether it is as necessary as others have claimed.
• Anna shares a story that makes her super happy about her cookbooks. (46:00)
• Vinnie is trying a week off from eating cheese, but he’s wrapping up the week with Anna’s Cheese Bites for the Super Bowl. (48:30)
• They conclude the episode with a discussion of discontinuing GLP-1s. Talk to your doctor for the proper protocol.
•  If you decide to continue GLP-1s, please start strength training to offset muscle loss.
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