Clinical Pharmacology: The Science Behind Safer, Smarter Cancer Therapies
Bench to Bedside
In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, interviews Dr. Brent Sear, director of the Clinical Pharmacology Shared Resource at KU Cancer Center. Brent shares his unique career journey into clinical pharmacology, the role of clinical pharmacology in advancing cancer therapies, and the critical work his team does in guiding clinical trials and personalizing cancer treatment. They also discuss emerging technologies and their potential impact on the future of cancer research. Tune in to learn more about...
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Looking Ahead: Hope and the Future of Cancer Research
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, hosts Dr. Kristy Brown, a nationally recognized expert in cancer metabolism and hormone signaling. Dr. Brown discusses the latest breakthroughs in understanding the relationship between obesity, estrogen, and cancer, along with how these discoveries shape more effective treatments. She reflects on her career and shares moving accounts of patient interactions that fuel her research. The conversation delves into emerging opportunities in cancer treatment and prevention,...
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It Takes a Village: The Power of Cross-Disciplinary Collaboration in Cancer Research
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen speaks with Dr. Anna Arthur and Dr. Gregory Gan about their innovative cross-disciplinary work at the intersection of nutrition and radiation oncology. They explore how their combined expertise leads to holistic cancer treatment approaches, focusing on the effects of diet, inflammation, and treatment response on patient outcomes. Both experts share their personal and professional journeys into their respective fields, the collaborative projects they have undertaken, and the way they integrate multidisciplinary insights into improving cancer...
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The Power of Patient Voices in Cancer Research
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, talks with Marilyn Mahan and Karl Frees, members of Patient and Investigator Voices Organizing Together (PIVOT) – KU Cancer Center’s patient research advocacy group – and co-chairs of the PIVOT Educational Task Force. They discuss PIVOT, an initiative bringing patients, survivors, caregivers, and researchers together to enhance cancer research. Marilyn and Karl share how PIVOT integrates patient perspectives into research, the ways advocates collaborate with...
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There’s No Place Like Home
Bench to Bedside
In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, speaks with Dr. Ronald Chen, chair of Radiation Oncology and associate director for Community Outreach and Engagement at KU Cancer Center. Dr. Chen shares his personal and professional journey from growing up in Topeka to Harvard and a career on the East Coast and back to Kansas, focusing on his motivation to return home and how his work impacts rural communities. He discusses his efforts in cancer care, telehealth and clinical trials, emphasizing the...
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The Science of Survivorship
Bench to Bedside
In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Anthony Sung and Dr. Jennifer Klemp, leaders in cancer survivorship research. They discuss their personal motivations, the importance of comprehensive survivorship care starting from diagnosis, and the innovative programs and research efforts at the KU Center for Survivorship and Patient-Oriented Research. The conversation highlights the challenges faced by cancer survivors, the need for individualized care, and the role of community support...
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This is Personal with Dr. Gary Doolittle
Bench to Bedside
In the season six premiere of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with his friend and colleague Dr. Gary Doolittle, medical director of the Masonic Cancer Alliance (MCA) and melanoma expert. Dr. Doolittle shares his personal and professional experiences in oncology, including his own cancer diagnosis and how it has influenced his approach to patient care. They discuss the unique challenges rural communities face in accessing cancer treatment and the role initiatives like the Masonic Cancer Alliance and...
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Advancing Progress Against Brain Cancer with Cell Therapy
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with Dr. David Akhavan, a physician-scientist pioneering cell therapy research for brain cancer. Dr. Akhavan discusses the revolutionary potential of chimeric antigen receptor (CAR) T-cell therapy in treating cancers like glioblastoma, the complexities involved and the innovative approaches his team is employing, such as smarter engineered T-cells and nanoparticles. Highlighting the collaboration within KU Cancer Center, Dr. Akhavan also shares personal...
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Voices of Suvivorship: The Wall of Hope at KU Cancer Center
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by two special guests: Paul Seyferth, a stage IV lung and prostate cancer survivor and creator of the Wall of Hope Project at KU Cancer Center, and Rebecca Keunen, clinical case manager lead at the cancer center and a cancer survivor herself. They discuss Paul's emotional journey through his diagnosis and the creation of the Wall of Hope installation, which features cancer patients' photos, videos and stories to inspire hope. Rebecca shares her involvement in...
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Cracking the Code: Research Sheds New Light on Ovarian Cancer Biomarker
Bench to Bedside
In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, sits down with Dr. Rebecca Whelan, an associate professor of chemistry at the University of Kansas and member of KU Cancer Center’s Cancer Biology research program. The discussion focuses on the limitations of the CA125 blood test for ovarian cancer detection and Dr. Whelan’s groundbreaking research, which reveals new insights into the structure of the CA125 protein. Dr. Whelan explains how new DNA sequencing technologies and artificial intelligence, specifically the...
info_outlineIn this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, hosts Dr. Kristy Brown, a nationally recognized expert in cancer metabolism and hormone signaling. Dr. Brown discusses the latest breakthroughs in understanding the relationship between obesity, estrogen, and cancer, along with how these discoveries shape more effective treatments. She reflects on her career and shares moving accounts of patient interactions that fuel her research. The conversation delves into emerging opportunities in cancer treatment and prevention, the role of artificial intelligence in research, and offers advice for early-career scientists on making a meaningful impact. Dr. Brown expresses optimism for future cancer research advancements and the potential for improved patient outcomes.
00:00 Introduction to the Podcast and Today's Topic
00:28 Meet Dr. Kristy Brown: Expert in Cancer Metabolism
01:02 Optimism in Cancer Research: Key Developments
02:31 Proud Moments in Cancer Research
04:15 Obesity, Metabolism, and Cancer: Emerging Discoveries
06:10 Translational Research: From Lab to Clinic
09:08 Advice for Early Career Scientists
12:18 Hope for the Future: Personal Reflections
13:24 Conclusion and Resources
Links from this Episode:
· Learn more about Dr. Kristy Brown
· Learn about Dr. Brown’s research
· Learn about cancer prevention at KU Cancer Center
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