#335 Unlocking VO2 Max: TIME-Saving Secrets (Why Zone 2 Alone Won’t Cut It) | REHIT and Metabolic Health With Ulrich Dempfle
LONGEVITY with Nathalie Niddam
Release Date: 05/16/2025
#353: Melatonin 101: Antioxidants, Gut Health, Sleep, Skin Protection, and Cancer Research with Nat Niddam
LONGEVITY with Nathalie Niddam
Today, I’m flying solo for a deep—well, more like a just-scratching-the-surface—dive into one of the body’s most fascinating hormones: melatonin. After getting so many of your questions about how melatonin really works, whether it’s just about sleep, and how it might support healthy aging, I decided to tackle all those hot topics head-on in this episode. Download my FREE guide to my top 5 peptides for longevity: What we discuss: Why melatonin is complex; plans for future episodes ... 00:00:42 Melatonin as darkness hormone; comparison with vitamin D ... 00:01:51...
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#352: Biohacker’s DREAM: How Plant Exosomes Deliver Cellular Power Like Never Before | Nathalie Niddam x Dr. Jeffrey Gross
LONGEVITY with Nathalie Niddam
Today, I’m welcoming back , a true pioneer in the regenerative longevity space. You might remember our earlier episode where we explored the transformative science of human exosomes—but today, we’re going even further, straight into the fascinating world of plant exosomes. Visit and use code NAT for 10% off What we discuss: Plant exosomes intro ... 00:04:23 Gut health/minerals ... 00:05:18 Why plant exosomes ... 00:08:09 Exosomes vs. liposomes ... 00:09:35 Bioavailability ... 00:12:12 Phytonutrients ... 00:17:26 Resveratrol ... 00:18:17 Quercetin ... 00:20:30 Glutathione ......
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#351: How to Rewire Your Gut (and Mind) For Health: Coffee, Microbiome DIVERSITY, and The Power of Belief | Dr. Vincent Pedre
LONGEVITY with Nathalie Niddam
Today, I’m joined by the brilliant , one of the most sought-after experts in functional medicine and an incredible advocate for what he calls “gut-centric medicine.” Together, we explore how your emotions and beliefs directly impact your gut, why there is no one-size-fits-all approach to gut healing, and the practical steps you can take to support your body’s natural balance. What we discuss: Dr. Pedre’s personal and medical background ... 00:06:05 Mind-body connection and overcoming fear through meditation ... 00:09:16 Impact of antibiotics and gut health journey ... 00:18:06...
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#350: Nature’s Longevity CODE Revealed: Exosomes, Plasma HACKS & the Real Science of Aging | With Dr. Ian White
LONGEVITY with Nathalie Niddam
In this episode, I sit down with —one of the most exciting researchers in regenerative medicine today. If you’re even a little bit curious about how to hack aging or have heard the buzz about things like plasma exchanges, exosomes, or why on earth lobsters never seem to grow old, you’re in for a treat. What we discuss: Expanding autologous hematopoietic stem cells and FDA challenges ... 00:08:28 Heterochronic parabiosis, plasma exchange, and aging signals ... 00:17:35 Nature’s clues: Lobsters, jellyfish, and biological age reset ... 00:24:02 Entropy, epigenetics, and limiting...
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#349: Jaw-Dropping Moments From The Last 6 Months: The Conversations Still Stuck in My Head With Nat Niddam (Solo)
LONGEVITY with Nathalie Niddam
Today, I've got something special for you: a solo episode where I look back at the past six months and handpick the five episodes and ideas that truly changed the game for me—and, based on your feedback, for many of you too. Episodes from this podcast: What I discuss: Exosomes for regeneration: cartilage, bone, and joint repair ... 00:02:19 Exosomes vs. PRP and stem cells—key differences ... 00:05:20 Managing inflammation before regenerative treatments ... 00:06:09 Exosomes in neurology & anti-aging ... 00:07:01 Regulation, safety, and advances in exosome therapy ......
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#348 The Overlooked Power of Your Lymphatic System in Longevity and Recovery (Fascia Release and Deep Healing EXPLAINED) with Dr. Stephanie Canestraro
LONGEVITY with Nathalie Niddam
I’m your host, Nathalie Niddam, and today I’m thrilled to bring you a truly fascinating conversation with Dr. Stephanie Canestraro—a chiropractor, functional medicine practitioner, and someone with an incredible personal story about overcoming chronic illness. Dr. Canestraro works with elite athletes, including NHL players, but her expertise comes from her own journey through mysterious health challenges that eventually led her to discover the vital role of the lymphatic system. What we discuss: Dr. Canestraro’s personal health journey and lymphatic issues ... 00:07:58...
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#347: Left vs Right Brain: The NEW Science Behind ADHD, OCD & Childhood Development With Dr. Robert Melillo
LONGEVITY with Nathalie Niddam
In this episode, I’m thrilled to sit down with , a clinical neuroscientist with nearly 40 years of experience decoding the mysteries of the brain and how our modern lifestyle—and especially technology—are changing it. If you’ve ever worried about what all that screen time means for your kids’ developing brains (or your own), this conversation is going to give you a whole new perspective. What we discuss: Left/right brain imbalance and modern tech’s impact ... 00:12:31 Gut health, peptides, and foundational health tips ... 00:05:37 Dr. Melillo’s journey, research, and...
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#346: How Wearables, Biological Age Tests, And AI Are Shaping the Future Of Longevity With David Korsunsky
LONGEVITY with Nathalie Niddam
Today I’m joined by my friend and fellow biohacker, Dave Korsunsky, founder of . In this episode, we take you on a journey through the evolution of biohacking—from the early days when continuous glucose monitors were a novelty and cryotherapy sounded like science fiction, all the way to the sophisticated, data-driven tools we have at our fingertips today. What we discuss: Dave’s journey: Heads Up Health and the rise of health data ... 00:08:18 Making sense of health metrics: Knowing if protocols work ... 00:10:06 GLP-1s: muscle loss risks, proper technique, and hydration ......
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#345: The IMMUNITY Gamechanger | Thymosin alpha-1 Peptide (Cancer, Aging & Autoimmune) with Nat Niddam
LONGEVITY with Nathalie Niddam
Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—a nutritionist, human potential and epigenetic coach, and devoted biohacker. Today, I’m tackling one of your most-requested topics: Thymosin Alpha 1, a peptide that keeps lighting up conversations in my communities. Resources from the episode: What we discuss: Overview of Thymosin alpha-1 ... 00:02:16 Medical uses, orphan drug status, and immune effects ... 00:03:53 Contraindications and vaccine adjuvant potential ... 00:05:01 Benefits in sepsis, infections, and elderly ... 00:07:40 Mechanisms of...
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#344: Mindset Over Mortality: Top Breakthroughs for EXTREME Longevity (And How to Think Like an Immortal) with James Strole
LONGEVITY with Nathalie Niddam
Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with , a beacon in the radical longevity space and the visionary founder behind People Unlimited and . James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to using code: "niddam" What we discuss: James Strole’s personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00...
info_outlineToday, I’m joined by Ulrich Dempfle, the innovative mind behind the CAROL Bike. Ulrich’s journey is fascinating—he started as a mechanical engineer in Europe, became a pioneer in hospital AI systems, and is now laser-focused on bringing cutting-edge fitness tech to regular people, like you and me.
What we discuss:
Zone 2 training: hype, benefits, and limitations ... 00:08:00
VO2 max: definition and importance for longevity ... 00:10:00
The impracticality and issues with Zone 2 for most people ... 00:15:00
Downsides of long-duration steady-state cardio ... 00:18:00
Why strength and mobility also matter ... 00:17:00
Carol Bike and REHIT: efficient fitness for longevity ... 00:31:00
REHIT’s proven VO2 max and metabolic improvements ... 00:36:00
Personalization and ease-of-use with Carol Bike ... 00:49:00
Carol Bike’s versatility: multiple workouts and app integrations ... 00:57:00
Who Carol Bike is for and safety notes ... 01:10:00
Carol Bike trial info, research, and closing ... 01:12:00
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