#342: Unlocking The Secret Code To Fasting: The Biohack for Hunger, Longevity & Energy (How Scientists Are Hacking Your CELLS) | Chris Rhodes
LONGEVITY with Nathalie Niddam
Release Date: 06/10/2025
LONGEVITY with Nathalie Niddam
In this episode, I’m thrilled to sit down with , a clinical neuroscientist with nearly 40 years of experience decoding the mysteries of the brain and how our modern lifestyle—and especially technology—are changing it. If you’ve ever worried about what all that screen time means for your kids’ developing brains (or your own), this conversation is going to give you a whole new perspective. What we discuss: Left/right brain imbalance and modern tech’s impact ... 00:12:31 Gut health, peptides, and foundational health tips ... 00:05:37 Dr. Melillo’s journey, research, and...
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Today I’m joined by my friend and fellow biohacker, Dave Korsunsky, founder of . In this episode, we take you on a journey through the evolution of biohacking—from the early days when continuous glucose monitors were a novelty and cryotherapy sounded like science fiction, all the way to the sophisticated, data-driven tools we have at our fingertips today. What we discuss: Dave’s journey: Heads Up Health and the rise of health data ... 00:08:18 Making sense of health metrics: Knowing if protocols work ... 00:10:06 GLP-1s: muscle loss risks, proper technique, and hydration ......
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Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—a nutritionist, human potential and epigenetic coach, and devoted biohacker. Today, I’m tackling one of your most-requested topics: Thymosin Alpha 1, a peptide that keeps lighting up conversations in my communities. Resources from the episode: What we discuss: Overview of Thymosin alpha-1 ... 00:02:16 Medical uses, orphan drug status, and immune effects ... 00:03:53 Contraindications and vaccine adjuvant potential ... 00:05:01 Benefits in sepsis, infections, and elderly ... 00:07:40 Mechanisms of...
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Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with , a beacon in the radical longevity space and the visionary founder behind People Unlimited and . James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to using code: "niddam" What we discuss: James Strole’s personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00...
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Welcome back to the Longevity Podcast! I’m so excited to share today’s episode with you, because it’s one that’s deeply personal and truly inspiring. I had the pleasure of sitting down with , a remarkable physician I met during one of the Sedona retreats I co-host. Although he began his career as a trauma and orthopedic surgeon in Germany, Dr. Tudor’s path soon led him far beyond traditional medicine. Now, he’s known for his transformative work in osteopathy, neural therapy, and the exploration of how trauma—both physical and emotional—can shape our health and longevity. ...
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Welcome back to the Longevity Podcast! I’m so excited for today’s episode, where I sit down with Chris Rhodes—nutritional biochemist, fasting researcher, and —to dive deep into one of the most fascinating emerging topics in longevity science: fasting mimetics. If you’ve ever wanted to get the regenerative, anti-inflammatory, and health-boosting effects of fasting, but struggled to actually fast for 36 hours or more (trust me, I get it!), this conversation is for you. Listeners of this podcast can visit and use code NAT FOR 20% off your first single purchase or subscription order....
info_outlineLONGEVITY with Nathalie Niddam
Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I’m excited to share another solo episode with you. Today, I’m diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime. Resources from the episode: • • • • • • What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive...
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I had the chance to sit down with one of the original pioneers of the biohacking movement: . You probably know Dave as the founder of Bulletproof, the mastermind behind putting butter in coffee, and the creator of Upgrade Labs and the Biohacking Conference. He’s also a four-time New York Times bestselling author. What we discuss: Biohacking’s relationship with longevity and functional medicine ... 00:10:47 The importance of energy, joy, and personalization in longevity ... 00:14:28 Democratizing lab tests and health optimization with AXO Health ... 00:24:00 Most common health...
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I’m joined today by Oliver Amdrup-Chamby, the co-founder of and a true trailblazer in supplement transparency and quality. We break down everything you need to know to become a more informed consumer, from how to avoid hidden contaminants like heavy metals, pesticides, and microplastics, to why oxidation in fish oil is such a big deal, and the real story behind protein powders—especially the plant-based ones. Listeners of this podcast get 20% off of protein, a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT...
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Today, I’m joined by —a double board-certified dermatologist, fellowship-trained Mohs and facial reconstructive surgeon, and an expert in all things skin cancer—plus, he’s as entertaining as he is knowledgeable. If you’ve ever wondered whether you should slather on sunscreen religiously, or if embracing more sunlight is actually good for you, we’re here to offer the clarity and nuance that’s so often missing from the conversation. Listeners of this podcast can receive 15% off of SunPowder when you go to (it’s .co not .com or else you won’t find it). What we...
info_outlineWelcome back to the Longevity Podcast! I’m so excited for today’s episode, where I sit down with Chris Rhodes—nutritional biochemist, fasting researcher, and CEO of Mimio Health—to dive deep into one of the most fascinating emerging topics in longevity science: fasting mimetics. If you’ve ever wanted to get the regenerative, anti-inflammatory, and health-boosting effects of fasting, but struggled to actually fast for 36 hours or more (trust me, I get it!), this conversation is for you.
Listeners of this podcast can visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order.
What we discuss:
Meet Chris Rhodes and his biomimetic research journey ... 00:05:18
Unlocking fasting benefits without prolonged fasting ... 00:09:10
Supplements vs. pharmaceuticals for longevity ... 00:10:53
Fasting protocols, timing, and metabolic switching ... 00:15:23
Risks of fasting, evolutionary adaptation, and muscle/bone loss ... 00:18:34
Ketones, brain energy, and cognitive adaptation ... 00:22:48
How fasting activates longevity and repair pathways ... 00:26:23
Key cellular pathways: AMPK, mTOR, NAD, sirtuins ... 00:28:04
Mimio research: discovering and testing fasting metabolites ... 00:33:35
The four main fasting mimetic molecules explained ... 00:42:04
Practical benefits: who should use fasting mimetics & safety ... 00:59:00
Mimio in use: hunger control, GLP-1 support, and older adults ... 01:03:37
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