#408: The Surprising Truth About Metabolomics, Stress, and Slowing Aging (Peptides, Heavy Metals & Foundational Health Secrets) With Gus Vickery
LONGEVITY with Nathalie Niddam
Release Date: 01/30/2026
LONGEVITY with Nathalie Niddam
Today, I’m joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather’s preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation. For Dr. Shivani’s Turmeric and sleep gummies visit and use code NAT15 for 15% off. Episode Timestamps: Welcome...
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Today, I’m joined by the inspiring —a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Health crisis and discovering personal optimization ... 00:07:05 From “sick care” to...
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Today, I’m sitting down with , a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine. If you’ve ever wondered whether skipping your foundational health habits “just for a little while” really matters, you’re about to find out. If you are a clinician and would like to offer the Aristotle test to your patients please use...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by the remarkable , a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction. Check out her book . Episode Timestamps: Introduction, podcast focus, and welcoming Dr....
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Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. Use code NAT10 for 10% off products at Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore’s path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular...
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Today, I’m joined by the deeply thoughtful and refreshingly honest , a self-described “curious cardiologist” who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it? Episode Timestamps: Welcome to Longevity & episode setup … 00:00:00 Dr. Bhojraj’s shift from ER cardiology to prevention … 00:06:30 Why most heart attacks aren’t caused by big blockages … 00:09:15 Stress, nervous system load & heart attack risk … 00:13:10 CIMT explained: what it measures...
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Today, I’m joined by , a true innovator in , and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Together, we take a deep dive into the unseen world of the water running through our homes—exploring not just its purity, but its hidden potential to support our biology in ways most of us have never considered. - Use code NAT100 Episode Timestamps: Intro to Longevity Podcast and today’s water focus ... 00:00:00 Water system’s health benefits and testing ... 00:01:33 Why water quality is overlooked yet critical ... 00:07:20...
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Today, I’m joined by Ben Katz—better known online as —an academic analytical chemist from UC Irvine whose mission is to uncover what’s really in our everyday foods, drinks, and products. Ben reverse engineers everything from Taco Bell meat to Doritos, and sometimes even entire industries, using cutting-edge mass spectrometry. His curiosity and expertise have made him a go-to source for those wanting to know what’s hiding behind vague ingredient labels and “natural flavors.” Episode Timestamps: Welcome and podcast introduction ... 00:00:00 What is mass spectrometry? ......
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Today, I’m kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we’ve explored everything from gene therapy to advanced tech, but it all comes back to the habits and systems we rely on every single day—and the gut is right at the center of that equation. Episode Timestamps: Gut health as the cornerstone of longevity ... 00:00:00 Why disease and wellness begin in the gut ... 00:03:46 Symptoms and signs of gut imbalance ... 00:08:53 Normalizing digestive discomfort ......
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Today, I’m joined by the insightful , renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss. Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of...
info_outlineToday, I’m sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine. If you’ve ever wondered whether skipping your foundational health habits “just for a little while” really matters, you’re about to find out.
If you are a clinician and would like to offer the Aristotle test to your patients please use this link to learn more about the Theriome test: therio.me/niddam
If you are a patient and would like to run the Theriome Aristotle test and get a full interpretation and protocol based on your results from Dr Vickery & his team please use this link: https://authentichealth.com/precision-health-evaluation/
Episode Timestamps:
Introduction to Longevity Podcast and episode overview ... 00:00:00
Metabolomics and interpreting health data – practitioner guidance needed ... 00:05:05
Combining metabolomics, gut, and blood data for whole-system insights ... 00:06:02
Nutrient depletion and oxidative stress: critical findings ... 00:18:57
Supplementation essentials for aging well ... 00:27:05
Metabolomics comparison by age group and optimization goals ... 00:29:03
Stacking interventions: why less is more with diagnostics ... 00:31:05
Functional health markers and the value of context ... 00:34:47
Sympathetic dominance, mindset, and impact on longevity ... 00:35:26
Restoring nervous system balance – inner work and tech tools ... 00:42:38
Toxins, heavy metals, and practical detox strategies ... 00:49:11
Clean environment, resiliency, and realistic lifestyle shifts ... 00:55:29
Key nutrient deficiencies revealed by metabolomics ... 01:09:15
Genetic and metabolomic tests: what’s actionable? ... 01:15:07
Hope for the future: human resilience and expanding technology ... 01:22:24
Weekly actionable: walk outside for mitochondria and stress relief ... 01:26:55
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