#409: How to LIVE YOUNG for a Lifetime: The Real Secrets of Mindset, Medicine & Longevity | Personalized Health Explained With Dr. Jeffrey Gladden
LONGEVITY with Nathalie Niddam
Release Date: 02/03/2026
LONGEVITY with Nathalie Niddam
Today, I’m joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather’s preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation. For Dr. Shivani’s Turmeric and sleep gummies visit and use code NAT15 for 15% off. Episode Timestamps: Welcome...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by the inspiring —a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Health crisis and discovering personal optimization ... 00:07:05 From “sick care” to...
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Today, I’m sitting down with , a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine. If you’ve ever wondered whether skipping your foundational health habits “just for a little while” really matters, you’re about to find out. If you are a clinician and would like to offer the Aristotle test to your patients please use...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by the remarkable , a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a “healthy sedentary person” and reveals the major role of intramuscular fat in metabolic dysfunction. Check out her book . Episode Timestamps: Introduction, podcast focus, and welcoming Dr....
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Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. Use code NAT10 for 10% off products at Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore’s path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular...
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Today, I’m joined by the deeply thoughtful and refreshingly honest , a self-described “curious cardiologist” who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it? Episode Timestamps: Welcome to Longevity & episode setup … 00:00:00 Dr. Bhojraj’s shift from ER cardiology to prevention … 00:06:30 Why most heart attacks aren’t caused by big blockages … 00:09:15 Stress, nervous system load & heart attack risk … 00:13:10 CIMT explained: what it measures...
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Today, I’m joined by , a true innovator in , and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Together, we take a deep dive into the unseen world of the water running through our homes—exploring not just its purity, but its hidden potential to support our biology in ways most of us have never considered. - Use code NAT100 Episode Timestamps: Intro to Longevity Podcast and today’s water focus ... 00:00:00 Water system’s health benefits and testing ... 00:01:33 Why water quality is overlooked yet critical ... 00:07:20...
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Today, I’m joined by Ben Katz—better known online as —an academic analytical chemist from UC Irvine whose mission is to uncover what’s really in our everyday foods, drinks, and products. Ben reverse engineers everything from Taco Bell meat to Doritos, and sometimes even entire industries, using cutting-edge mass spectrometry. His curiosity and expertise have made him a go-to source for those wanting to know what’s hiding behind vague ingredient labels and “natural flavors.” Episode Timestamps: Welcome and podcast introduction ... 00:00:00 What is mass spectrometry? ......
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Today, I’m kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we’ve explored everything from gene therapy to advanced tech, but it all comes back to the habits and systems we rely on every single day—and the gut is right at the center of that equation. Episode Timestamps: Gut health as the cornerstone of longevity ... 00:00:00 Why disease and wellness begin in the gut ... 00:03:46 Symptoms and signs of gut imbalance ... 00:08:53 Normalizing digestive discomfort ......
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Today, I’m joined by the insightful , renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss. Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of...
info_outlineToday, I’m joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept “normal for your age” as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.
Episode Timestamps:
Welcome and episode introduction ... 00:00:00
Health crisis and discovering personal optimization ... 00:07:05
From “sick care” to health optimization ... 00:10:46
Vision for personalized, youthful longevity ... 00:12:17
Personalized medicine: why one size doesn’t fit all ... 00:16:00
Linear versus exponential aging; fixing a flawed approach ... 00:18:02
Five circles of exponential health: key longevity domains ... 00:19:23
Curiosity, growth mindset, and quantum thinking in longevity ... 00:22:22
Why individualization is crucial for diet and interventions ... 00:28:52
Insulin resistance: the hidden driver of aging ... 00:33:41
Environmental and internal (psychospiritual) factors in health ... 00:38:40
Healing through meditation, stress management, and flow ... 00:41:15
Robustness, resilience, and anti-fragility as longevity superpowers ... 00:57:09
Safe, personalized hormone therapy and the importance of tracking ... 01:03:33
Integrating mindset, purpose, and psycho-spiritual work ... 01:08:50
Peptides and advanced therapies: preparing for optimal results ... 01:09:56
Common test misconceptions in longevity medicine ... 01:12:56
Debunking the myth of single biological age ... 01:16:38
Resources, connect with Dr. Gladden, and closing ... 01:18:09
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