#412: From Anti-Aging to Age Reversal: The Exosome & Copper Peptide Breakthrough For Younger Skin With Debbi Barber and Dr. Jordan Plews
LONGEVITY with Nathalie Niddam
Release Date: 02/13/2026
#427: The Hidden Link Between Vision, Longevity & Anxiety | Spatial Empathy, Screens & the 20-20-20 Rule With Dr. Meenal Agarwal
LONGEVITY with Nathalie Niddam
Today, I’m joined by the insightful , an eye doctor and passionate advocate for reimagining how we think about vision and brain health. In our conversation, Dr. Agarwal reveals the surprising ways our daily screen habits are shaping not just our eyesight, but also our emotional regulation, cognitive performance, and even the development of anxiety and ADHD-like symptoms. She opens up about her own journey—from an unexpected period of cognitive “off-ness” during a stint away from her clinical work, to pioneering a powerful perspective on “spatial awareness processing disorder.”...
info_outline
#426: The Invisible Price of Poor Sleep and How To Fix It, Tech Hacks That Save Marriages, and the Longevity Equation — With Melissa Urban
LONGEVITY with Nathalie Niddam
Today, I’m joined by the amazing , the force behind Whole30 and a global champion of accessible nutrition. In our conversation, Melissa opens up about a surprising discovery in her wellness journey: sleep, not just food, is often the real foundation of long-term health. She shares how overlooked sleep hijacked her cravings, impacted her insulin sensitivity, and even chipped away at her resilience—revealing the invisible costs that only show up years down the line. Visit and use code NAT to get $95 off Episode Timestamps: Welcome and podcast introduction ... 00:00:00 Poor...
info_outline
#425: Broccoli Power: The Secret Longevity Molecule (Fighting Toxins, Microplastics & Aging) | Sulforaphane Exposed With David Roberts & Dr. John Gildea
LONGEVITY with Nathalie Niddam
Today, I’m joined by , two passionate researchers whose work sits at the cutting edge of environmental health and longevity science. In this episode, we dive deep into the catalyst for developing a stabilized sulforaphane supplement—something born out of both necessity and relentless curiosity. David opens up about how environmental toxicity stopped being theoretical for him, and Dr. Gildea brings a wealth of clinical insight into why supporting our detox pathways could be a game-changer for chronic disease prevention. Offer: Get 25% off stabilized sulforaphane products for a limited time...
info_outline
#424: Part 2 - Follow Up To Dr. Bill Lawrence Episode: Answering More Of Your Bioregulator Questions With Nat Niddam & Erin Ryan
LONGEVITY with Nathalie Niddam
Today, I’m joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After the wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries—from cancer concerns to menopause, sourcing, and practical tips. Books mentioned in this episode: (Great primer on bioregulators) Author: Dr. Marios Kyriazis (Technical, science-heavy) Author: , , Episode Timestamps: Welcome and sponsor introduction ... 00:00:00 Autophagy and Primadene ......
info_outline
#423: Detox Pathways, Sensitive Systems, and the Truth About Chelation Therapy With Dr. Nafysa Parpia
LONGEVITY with Nathalie Niddam
Today, I’m joined by the insightful , a true leader in environmental and complex chronic illness medicine and the Director of Naturopathic Medicine at Gordon Medical. In our conversation, Dr. Parpia shares how her passion for deep, integrated healing brought her into the world of environmental toxins, hormone health, and the nuanced ways our bodies respond to the modern world. She opens up about her journey, the unique challenges women face—especially during menopause—and why so many aren’t finding answers in traditional medicine. Episode Timestamps: Welcome & episode goals...
info_outline
#422: Lessons from Centenarians: Immunity, Lifestyle, and Changing the Aging Game With Dr. Jeffrey Bland
LONGEVITY with Nathalie Niddam
Today, I’m joined by the legendary , widely known as the “father of functional medicine” and a true pioneer in the science of longevity and immune resilience. In this conversation, Dr. Jeffrey Bland opens up about his decades-long journey questioning the conventional medicine model, the personal moments that shaped his mission, and how his passion for asking the right questions ultimately led him to reshape the future of healthcare. Visit and get 15% off automatically at checkout. Episode Timestamps: Focus on immune system aging ... 00:00:00 Questioning conventional medicine and...
info_outline
#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian
LONGEVITY with Nathalie Niddam
Today, I’m joined by , an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity. The...
info_outline
#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny
LONGEVITY with Nathalie Niddam
Today, I'm joined by the inspiring , Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable. Leslie has a generous offer for you, when you visit and use code BIONAT20 at...
info_outline
#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana
LONGEVITY with Nathalie Niddam
Today, I’m joined by the extraordinary , a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age. Episode Timestamps: Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00 Maternal inheritance and critical functions of mitochondria ... 00:05:56 Mitochondria as...
info_outline
#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum
LONGEVITY with Nathalie Niddam
Today, I’m joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health. If you want to try Endotelio 1-MNA and save 10% and code NAT10 will be entered for you at checkout. Episode Timestamps: Welcome and introduction to Longevity Podcast ......
info_outlineToday, I’ve got a conversation that goes deep into the cutting edge of regenerative skin health with two exceptional guests: Debbi Barber, founder and muse of Vitali Skincare, and Dr. Jordan Plews, a biochemical engineer and stem cell researcher. We discuss the science and practical realities of exosomes, stem cells, and copper peptides—breaking down not just what makes skin look younger, but what truly keeps it biologically healthier and more resilient as we age.
Visit https://www.vitaliskincare.com/?ref=Nat20 and use code Nat20
Episode Timestamps:
Welcome and podcast purpose ... 00:00:00
Shift from beauty to science and health ... 00:09:23
GHK-Cu’s role in longevity and skin repair ... 00:10:15
Dr. Plews on regenerative medicine and stem cells ... 00:11:14
From peptides to exosomes: product evolution ... 00:13:35
Stem cell exhaustion and need for exosome signaling ... 00:14:07
Copper peptides vs. exosomes: complementary actions ... 00:18:00
Why source and age of exosomes matter ... 00:25:20
Quality, safety, and labeling in exosome products ... 00:35:01
How exosomes and peptides benefit skin deeper layers ... 00:44:35
Visible results: barrier, redness, scars, texture ... 00:58:05
What to expect: younger vs. older skin ... 01:00:01
Proof and stories: customer transformations ... 01:01:59
More isn’t better: exosome dosing myth ... 01:07:03
Supporting ingredients: vitamin C, glutathione, SOD2 ... 01:11:31
Skin as a window into systemic aging ... 01:19:08
The future: personalized, organ-targeted exosome therapies ... 01:24:02
Our Amazing Sponsors:
Nature’s Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.
Manukora Honey - rich, creamy Manuka honey packed with powerful bioactives, all in just one heaped teaspoon a day. Go to MANUKORA.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit.
PW1 by Puori — A clean, high-quality whey protein that’s third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.
Nat's Links: