Breaking “Wine O’Clock”: Psilocybin, Saffron, Microdosing and Upgrading Women’s Mental Health with Keegan Downer
Release Date: 02/19/2026
Q&A: Your Intuition Directly Impacts Your Health, Censorship Online, and My Favorite NAD+ Nasal Spray and GHK-Cu Cream
Biohacking with Brittany
In this Q&A I get honest about getting banned on TikTok, the manifestation moment that turned it around, and the piece of women's health I think almost everyone is missing. Then I answer your questions on longevity, the two new products I am using right now, and what I've planned for the fall. Work with me one on one. I am opening a limited number of spots in my new inner circle, a three month program built around all six health pillars, including the intuition work. Book a free 15 minute discovery call and I will walk you through it: In this episode: 1:32 Why I got banned on...
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My Personal Peptide Stack and Why I'm Taking a Break: BPC-157, TB-500, Microdosing Retatrutide, AOD-9604, GHK-Cu, NAD, Selank and Semax
Biohacking with Brittany
I'm a biohacker with a peptide fridge, and right now I am injecting absolutely nothing. That is probably not what you expected me to say. The internet makes it look like the goal is more compounds, stacked higher, forever. It is not. The goal is to use the right tool for a specific window, then come off it. In this solo episode I open my actual fridge. I walk through every peptide I have run recently, the real dose, why it went in, why it came out, and why I am on a full break right now. I cover my injury repair pair BPC-157 and TB-500, my body composition experiments with AOD-9604 and a...
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Peptides Just Got National Validation: Inside the Landmark FDA Vote on BPC-157, TB-500, KPV, MOTS-c, DSIP, Epitalon + Semax
Biohacking with Brittany
This is a landmark day for peptides! I recorded this at 6 AM the morning between day one and day two of the FDA's Pharmacy Compounding Advisory Committee (PCAC) meeting, and I'm breaking down exactly what happened, why it matters, and what it means for you depending on where you live. On day one, the committee voted YES on all four peptides they reviewed: BPC-157, TB-500, KPV, and MOTS-c. This went against the FDA scientists' own recommendation. There was an audible gasp in the room. Today they're voting on DSIP, Epitalon, and Semax, and I expect all three to pass too. If you'd like to work...
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Optimize your Blood Sugar: Belly Fat, Prediabetes, Peptides, Type 3 & 4 Diabetes, Insulin Resistance, CGMs, Inositol and GLP-1's | Her Stack Series
Biohacking with Brittany
Blood sugar is the master dial. If your energy crashes at 3pm, if the cravings run you, if the belly weight will not move no matter how clean you eat, this is not a willpower problem. It is a blood sugar problem, and it is fixable. In this episode I break down blood sugar for women from the ground up: what glucose and insulin actually do, the six levers that throw them off, the full diabetes spectrum from prediabetes through Types 1 to 4 (including the lean, skinny fat Type 4 that surprised me), and the exact labs and CGMs to run. Then I give you my full stack across four pillars: nutrition,...
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How to Glow Up in 8 Weeks: Supplements, Collagen, Biohacks and Peptides (GHK-Cu, Retatrutide, MOTS-c, AOD 9604) | Her Stack Series
Biohacking with Brittany
You have a wedding, a vacation, a babymoon, a reunion, or a big shoot in about two months, and you want to walk in glowing. In this episode I give you my full 8 week glow up protocol, the same one I build for my one on one clients, and it is all from the inside out. I break down what glow actually is on a physiological level: collagen, glycation, inflammation and puffiness, gut health, circulation and lymph, and body composition. Then I walk you through the labs to run, my three pillars of nutrition, lifestyle, and supplements, and the peptides I reach for when a client wants skin, hair, tan,...
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The Complete Sleep Protocol: Peptides, Supplements, Blood Sugar, Blue Light, Cooling Mattresses + The 3 AM Fix That Changed Everything | Her Stack Series
Biohacking with Brittany
In this episode, I'm giving you the full sleep protocol I built for myself and for the women I work with. Not just how to sleep longer, but how to make the hours you actually get deeper, more restorative, and more efficient. Even if you have a kid in your bed. Even if you are perimenopausal and running hot. Even if you have been broken for years. I share the exact protein-before-bed hack that ended my 3 AM wake-ups, the caffeine half-life math (why your 2 PM coffee is still in your system at 10 PM), why I do not recommend melatonin for most women, the 3 sleep peptides I trust the most (DSIP,...
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The Complete Perimenopause Protocol: Peptides, HRT, Labs, Nutrition, Workouts & Supplements That Actually Work | Her Stack Series
Biohacking with Brittany
Perimenopause is not a slow fade. It is a hormonal storm that lasts about a decade. Estrogen swings, progesterone slips first, testosterone quietly declines, and growth hormone falls alongside all of it. That is why the workout that worked at 25 stops working at 45. It is why women come to me saying "I am doing everything right and the scale will not budge." Your biology is changing, and your approach has to change with it. In this episode I'm giving you my top recommendations for every pillar so you walk away with a real protocol, not a pile of overwhelm. We cover the exact biomarker labs to...
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Q&A: Where Would We Raise Our Family in Central America?, Wolverine Blend vs. Singles, Selank Peptide vs. Psilocybin & GHK-Cu Body Cream
Biohacking with Brittany
This week is a Q&A episode in two parts. In Part 1, I give you the honest, real-numbers breakdown of the four Central American countries we keep weighing for our family: Nicaragua, Costa Rica, Panama, and Mexico. Rent, nannies, food, healthcare, schools, and flights from Canada. In Part 2, I answer three of the peptide questions you sent me: the Wolverine blend for an ACL tear, Selank vs psilocybin microdosing, and whether GHK-Cu actually works in a body cream. Join for women-specific guidance on peptides, hormones, and longevity. Timestamps: 04:00 - The four-country...
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Body Composition Protocol for Women: Peptides, Growth Hormone, Protein, GLP-1s & The Complete Metabolic Reset | Her Stack Series
Biohacking with Brittany
Your body after a baby was never a calorie problem. It is a metabolic one. In this Her Stack episode I am walking you through exactly how to restore your metabolism so body composition follows. The goal is not weight loss. The goal is metabolic restoration. Body comp is downstream. I am breaking down the four drivers that actually run body composition (insulin, thyroid, sleep, growth hormone), the four pillars to address them (nutrition, lifestyle, supplements, peptides), and the exact peptide sequencing for women. Plus my honest take on GLP-1s including semaglutide, tirzepatide, and...
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Q&A: Peptides for Breastfeeding, Postpartum Weight Loss, Cancer History & How to Build Your Stack | Her Stack Series
Biohacking with Brittany
In this Q&A episode of the Her Stack Series, I'm answering the peptide questions you're asking me every single day in my DMs and comments: → Can I take peptides while breastfeeding? → What if I have a personal or family history of cancer? → Why won't my postpartum belly fat budge, even when I'm doing everything "right"? → Blends vs. single peptides, which is right for me? → How do I build my own peptide stack without ending up on eight injections a day? I'm unfiltered in this one. I share why there will never be clinical trials on peptides during breastfeeding (and what...
info_outlineKeegan Downer (Founder of mindfulMEDS) shares how he went from alcohol addiction and a near-suicidal breaking point, to recovery and to building one of Canada’s most recognized microdosing education brands, and why psilocybin doesn’t have to be “woo.”
We also get super practical: What microdosing actually feels like day-to-day, why it can hit women differently (especially moms), how psilocybin compares to SSRIs (Selective Serotonin Reuptake Inhibitor) when it comes to emotional processing, and why “wine o’clock” culture is quietly keeping so many women stuck in a stress-and-numb cycle.
Want protocols built specifically for women, live coaching, and real talk about peptides and longevity? That's what The LongHer Life is for. Private. Uncensored. Ongoing. https://biohackingbrittany.com/pages/longherlife
WE TALK ABOUT:
05:40 - Keegan’s life collapse that led to addiction and the “rooftop moment”
07:45 - Rebuilding purpose after rehab and the anxiety attack that changed everything
09:10 - Why microdosing went from “nobody’s talking about this” to mainstream fast
12:35 - The day-13 breakthrough and the microdosing study that launched his mission
19:30 - Why psilocybin and SSRIs create totally different emotional outcomes
23:20 - When microdosing feels “too strong” and how dose + setting change everything
28:40 - The dose reality check: “microdose” vs “creative dose” and why sensitivity matters
38:20 - Why women (especially moms) are the fastest-growing microdosing segment
41:05 - “Wine o’clock” culture, addiction masking, and the uncomfortable truth
44:00 - Brainbow: The saffron extract approach for mood, sleep, and nervous system support
57:10 - Where to learn more, the free microdosing guide, and weekly consults
RESOURCES:
Want protocols built specifically for women, live coaching, and real talk about peptides and longevity? That's what The LongHer Life is for. Private. Uncensored. Ongoing. https://biohackingbrittany.com/pages/longherlife
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