Breaking “Wine O’Clock”: Psilocybin, Saffron, Microdosing and Upgrading Women’s Mental Health with Keegan Downer
Release Date: 02/19/2026
Breaking “Wine O’Clock”: Psilocybin, Saffron, Microdosing and Upgrading Women’s Mental Health with Keegan Downer
Biohacking with Brittany
Keegan Downer (Founder of ) shares how he went from alcohol addiction and a near-suicidal breaking point, to recovery and to building one of Canada’s most recognized microdosing education brands, and why psilocybin doesn’t have to be “woo.” We also get super practical: What microdosing actually feels like day-to-day, why it can hit women differently (especially moms), how psilocybin compares to SSRIs (Selective Serotonin Reuptake Inhibitor) when it comes to emotional processing, and why “wine o’clock” culture is quietly keeping so many women stuck in a stress-and-numb...
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The Feminine Longevity Shift: How Misalignment Shows Up in the Female Body (and What Actually Restores It)
Biohacking with Brittany
In Day 2 of The Feminine Longevity Shift free live masterclass, I unpack why so many women are doing “everything right”. Yet still feel inflamed, exhausted, or disconnected. This isn’t about more discipline or optimization. It’s about recognizing how misalignment shows up in the female body and what actually supports long-term vitality, hormonal resilience, and healthy aging. Join my NEW private community at for ongoing protocols, live coaching, and deeper support. I TALK ABOUT: 05:45 - Connecting women’s longevity to intuition and low-grade stress you don’t notice until you...
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The Feminine Longevity Shift: Why Women Age Faster When They’re Out of Alignment
Biohacking with Brittany
In this free live masterclass, I connect the dots between women’s healthspan, chronic stress, and the biological cost of living out of alignment. Even when your habits look “healthy.” I talk about why the longevity conversation has been dominated by male-centered frameworks, and what happens when women override their intuition for years (in work, relationships, family dynamics, and daily decisions). This is an invitation to stop treating intuition like a “soft” topic—and start seeing it as a health input that shapes inflammation, hormones, nervous system regulation, and...
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Why “Calm” Feels Impossible for Women: Trauma, Sensory Overload, and the Real Path Back to Safety with Dr. Holly Duckworth
Biohacking with Brittany
Dr. Holly Duckworth (PhD) shares how she went from mechanical engineering → psychology → deep hypnosis work (QHHT), and why “higher self” doesn’t have to be woo. Especially when you understand how fear, trauma responses, and nervous system dysregulation run the show. We also get super practical: How to recognize dysregulation (hello, sensory sensitivity + road rage), why “therapy doesn’t work” for some people until the body is regulated first, and how gratitude + nature can become daily tools for coming back to safety. Join my NEW private community at for ongoing protocols,...
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NAD, Senolytics, Stem Cells: The Longevity Stack That Might Actually Move the Needle with Dan Pardi of Qualia
Biohacking with Brittany
Modern longevity culture can make “the perfect protocol” feel like the answer—especially when you’re a busy mom who wants more energy now and a longer healthspan. Dan Pardi from (code: BRITTANY) breaks down what’s changed in longevity science over the last 25 years—and why “healthspan” (feeling strong, clear, and capable for longer) matters more than simply living longer. We get into the real trade-offs of fasting, protein, and vitality, plus a clear explanation of what stem cells actually do, why they decline with age, and how “stem cell wellness” differs from...
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Why Canada No Longer Works for My Health, Family, or Business (A Life, Business, and Longevity Update)
Biohacking with Brittany
I’m recording from Nicaragua with a real-time life + business update because everything is shifting. I’m rebranding beyond “biohacking” into women’s longevity, intuitive health, and living in alignment. I’m also introducing , my private community with weekly protocols, biweekly calls + Q&As, and exclusive guest interviews. And I’m sharing why my family is in Central America, what we’re optimizing for with Callahan, and why we’re considering a nature-first move. If you want health to feel simpler and more sustainable, this episode is for you. I TALK ABOUT: 04:45 -...
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Biohacking Won’t Save You If Your Life Is Misaligned: The Missing Longevity Conversation with Oluwatobiloba
Biohacking with Brittany
Modern women are doing the most—tracking, supplementing, optimizing—yet still feel tired, inflamed, and strangely off. And sometimes the issue isn’t another protocol. It’s the life you’re living. Queen Oluwatobiloba explores women’s holistic wellness through a lens we don’t talk about enough: alignment. We unpack how your environment can mirror your internal season, why “being stuck” drains your vitality, and how discomfort is often the clearest sign you’re choosing something true. We also go into motherhood as an initiation (and why mom guilt is so biologically sticky),...
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Why Hustle Culture Creates Emotionally Numb Women (And What Actually Brings You Back) with Silvia Resnik
Biohacking with Brittany
Modern success can humble your nervous system fast. Especially when your life looks “perfect” on paper, but your body feels flat, restless, or quietly done. Silvia Resnik unpacks the hidden ache so many high-achieving women carry: doing everything “right” and still feeling unfulfilled. We explore the subtle signs of misalignment, how productivity becomes a coping strategy, and why nervous system safety is often the missing piece behind burnout and people-pleasing. We also get into what it actually looks like to rebuild self-trust without blowing up your whole life—tiny, brave choices...
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Detox Culture Is Lying to You: Why Cleanses Can Make Women Worse (and What to Do Instead) with Eva Hooft
Biohacking with Brittany
Modern motherhood can make “detox” feel like the answer—especially when you’re exhausted and convinced you just need the right protocol to get your body back. Eva Hooft unpacks why the do-more, cleanse-harder mindset can keep women stuck, and how real healing starts with safety, not force. We talk detox through a nervous system + mineral lens: how stress shuts down digestion and drainage, why aggressive “pulling” can backfire when you’re depleted, and what it looks like to rebuild your terrain with simple, foundational support. We also get real about the emotional side—when...
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Let’s Be Real: The IVF Stats No One Talks About with Gabriela Rosa
Biohacking with Brittany
If you have been trying for a baby (or you are not even trying yet but you feel that quiet fear in the background), this conversation is a reset. Gabriela Rosa is a leading practitioner in preconception and infertility care, and she explains why fertility is a team sport, why prevention beats panic, and what actually moves the needle for both partners. WE TALK ABOUT: 00:10 - Why preconception health is the missing “first step” most couples skip 05:15 - How fear of infertility starts before you even try 07:15 - Making fertility a team sport so the burden is not on women alone...
info_outlineKeegan Downer (Founder of mindfulMEDS) shares how he went from alcohol addiction and a near-suicidal breaking point, to recovery and to building one of Canada’s most recognized microdosing education brands, and why psilocybin doesn’t have to be “woo.”
We also get super practical: What microdosing actually feels like day-to-day, why it can hit women differently (especially moms), how psilocybin compares to SSRIs (Selective Serotonin Reuptake Inhibitor) when it comes to emotional processing, and why “wine o’clock” culture is quietly keeping so many women stuck in a stress-and-numb cycle.
Join my NEW private community at thelongherlife.com for ongoing protocols, live coaching, and deeper support.
WE TALK ABOUT:
05:40 - Keegan’s life collapse that led to addiction and the “rooftop moment”
07:45 - Rebuilding purpose after rehab and the anxiety attack that changed everything
09:10 - Why microdosing went from “nobody’s talking about this” to mainstream fast
12:35 - The day-13 breakthrough and the microdosing study that launched his mission
19:30 - Why psilocybin and SSRIs create totally different emotional outcomes
23:20 - When microdosing feels “too strong” and how dose + setting change everything
28:40 - The dose reality check: “microdose” vs “creative dose” and why sensitivity matters
38:20 - Why women (especially moms) are the fastest-growing microdosing segment
41:05 - “Wine o’clock” culture, addiction masking, and the uncomfortable truth
44:00 - Brainbow: The saffron extract approach for mood, sleep, and nervous system support
57:10 - Where to learn more, the free microdosing guide, and weekly consults
RESOURCES:
Join my NEW private community at thelongherlife.com for ongoing protocols, live coaching, and deeper support.
Join me in Costa Rica for Optimize Her, a 5-night luxury women’s retreat with biohacking, yoga, healing rituals, and longevity workshops—only 2 spots left.
Download the non-toxic baby registry guide to reduce toxic exposure and make confident, evidence-informed choices for your family—free.
Mindful Meds website and Instagram
Get The Mindful Meds Microdosing Guide here
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