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In the News, Oral insulin for T1D moves forward, T2D drug helps hearts, type 1 and teen brains and more

Diabetes Connections | Type 1 Diabetes

Release Date: 09/02/2022

What’s ahead for Tandem Diabetes? An update on pumps, CGMs, infusion sets, and more! show art What’s ahead for Tandem Diabetes? An update on pumps, CGMs, infusion sets, and more!

Diabetes Connections | Type 1 Diabetes

This week on Diabetes Connections, Tandem Diabetes made some big announcements at the recent ADA Conference – we’re going behind the headlines and asking your questions about Control IQ updates, extended wear infusion sets, what’s happening with their patch pumps, and a lot more. I’m talking to Ben Mar the Director of Product marketing. We also getting into their expanded partnership with Abbott – in additional to the Libre 3 plus, they’re one of the pump companies that has signed on for the future glucose/ketone sensor. A lot to get to here! This podcast is not intended as medical...

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In the News...Top Stories from ADA and more! show art In the News...Top Stories from ADA and more!

Diabetes Connections | Type 1 Diabetes

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: loads of news from American Diabetes Association Scientific Sessions, GLP1 for T1D, Tech updates, diabetes in space, and more! Find out more about  Please visit our Sponsors & Partners - they help make the show possible! Learn more about   from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Here's where to find us: Learn more about everything at our home page  Reach...

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Still Not Waiting: Lane Desborough's Bold New Push with Nudge show art Still Not Waiting: Lane Desborough's Bold New Push with Nudge

Diabetes Connections | Type 1 Diabetes

This week on Diabetes Connections, “We are not waiting” became more than just a slogan — it sparked a movement. Back when the diabetes community was fed up with slow progress, DIYers stepped in with solutions that actually worked better than what companies were offering. That rallying cry? It came from Lane Desborough in 2013. And more than a decade later, he’s still challenging the status quo. We’re catching up with Lane to talk about his latest project, Nudge — much more than just another insulin pump algorithm, it’s an innovation to create more open and accessible systems This...

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Cloak the Poke: A New Way to  Make Shots Less Scary show art Cloak the Poke: A New Way to Make Shots Less Scary

Diabetes Connections | Type 1 Diabetes

As we gear up for ADA Scientific Sessions and get ready to hear studies and reports from the big diabetes companies, I’ve decided to highlight something on the other end of the spectrum. College students, seeing a need and developing a solution. Cloak The Poke is all about addressing fear of needles, especially in kids. We’ll explain how it works,  more about the team behind it, and their big goals going forward. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. More about Join us at  Please visit...

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In the News... Omnipod updates, Tandem + Abbott, Dr. Pepper Zero recall, American Ninja and more! show art In the News... Omnipod updates, Tandem + Abbott, Dr. Pepper Zero recall, American Ninja and more!

Diabetes Connections | Type 1 Diabetes

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: what is adaptive biobehavioral control for AID systems? Omnipod 5 launches iOS app with Dexcom G7 compatability and a comic book(?!), Tandem and Abbott announce new partnership, Katie Bone is back on American Ninja Warrior, and more! Find out more about  Please visit our Sponsors & Partners - they help make the show possible! Learn more about   from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our...

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GLP-1 Medications for T1D:  What your endo wants you to know show art GLP-1 Medications for T1D: What your endo wants you to know

Diabetes Connections | Type 1 Diabetes

More and more people with type 1 are using GLP-1 receptor agonists. You know these medications, with brand names like Ozempic, Mounjaro, Wegovy and Zepbound, but none of them are specifically approved to treat T1D. Some of the first studies are underway to study the safety and effectiveness of GLP-1s, but that hasn’t stopped thousands of using them off-label or to treat obesity. We’re talking to an endocrinologist and a clinical pharmacist about why they prescribe these meds to some of their type 1 patients, who they won’t prescribe them for, and – I know you’re already asking –...

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Why Diabetes Camp Matters More Than Ever:  A Conversation with DECA’s Lisa Gier show art Why Diabetes Camp Matters More Than Ever: A Conversation with DECA’s Lisa Gier

Diabetes Connections | Type 1 Diabetes

It’s time to talk about summer camp! Kids may be getting ready to go, already there, or maybe you’re an adult with type 1 who has fond memories or is working at camp.  We’re talking to the which serves the diabetes camp community. Lisa Gier is the executive direction of DECA – she lives with type 1, attended camp and her son who also has T1D now goes to the camp she attended as a child. This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Join us at  Please visit our Sponsors &...

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Tubeless, smarter & interoperable: A look into Medtronic’s future plans show art Tubeless, smarter & interoperable: A look into Medtronic’s future plans

Diabetes Connections | Type 1 Diabetes

A conversation with a Medtronic engineer who’s been with the company since the beginning of the Artificial Pancreas project. Lou Lintereur is now Chief Engineer for AID systems at Medtronic.. we talk about the recently approved Simplera Sync Sensor, changes coming to Medtronic pumps, he answers your questions about AI use, patch pumps, and the idea of a pump that needs zero user interaction. Note: this episode was recorded before Medtronic's announcement that they will spin off the Diabetes division. This podcast is not intended as medical advice. If you have those kinds of questions, please...

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"The Worst Game Ever" - Sam Glassenberg wants to change how we learn about T1D

Diabetes Connections | Type 1 Diabetes

Learning through video games isn’t new – there are games aimed at almost every profession, even healthcare.  Sam Glassenberg is the founder of Level Ex which makes those types of learning games –  and when his daughter was diagnosed with type 1.. he was appalled at the on-boarding process which he called the worst game ever, full of frustration and punishment for the patient and caregiver. So Sam developed Level One – a new free game to teach type 1. We’re talking about how it works, who it’s for, and what makes it different from those gamification flops you may remember...

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In the News...Tandem's new infusion set approved, Sernova cell-pouch moves forward, GLP-1 meds for T1D, and more! show art In the News...Tandem's new infusion set approved, Sernova cell-pouch moves forward, GLP-1 meds for T1D, and more!

Diabetes Connections | Type 1 Diabetes

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Tandem's new infusion set is approved, Dexcom G7 compatibility with the Omnipod 5 iPhone app announced, Sernova cell-pouch moves forward, GLP-1 meds for T1D, and more! Find out more about  Please visit our Sponsors & Partners - they help make the show possible! Learn more about   from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Here's where to find us: Learn more...

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More Episodes

It’s in the news! The top stories and headlines around the diabetes community this week include new progress in the quest for oral insulin to treat type 1, a new study says a common type 2 diabetes drug may help those with serious heart condition, a look at teen brains and T1D, NSAID and type 2 and more!

Learn about the T1d Exchange: www.t1dexchange.org/stacey 

Check out Stacey's book: The World's Worst Diabetes Mom!

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Episode Transcription Below (or coming soon!)

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Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and these are the top diabetes stories and headlines of the past seven days.
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In the news is brought to you by T1D Exchange! T1D Exchange is a nonprofit organization dedicated to improving outcomes for the entire T1D population.
https://t1dexchange.org/stacey/
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Our top story.. very early on here, but some progress in oral insulin for type 1. A team at University of British Columbia has developed a different kind of tablet that isn't made for swallowing, but instead dissolves when placed between the gum and cheek. This method delivered all the insulin to the liver without wasting or decomposing any insulin along the way. That’s a big change from earlier studies and methods. The oral tablets absorb after about half an hour and last for up to four hours.. long way to go, no human trials yet. The the lead researcher on this project has a father with type 1 .
https://www.sciencedaily.com/releases/2022/08/220830093215.htm?fbclid=IwAR1AzjI5UJma9I6g4hST044FS0MbJnUA0EXCmKXyhcOiOKL-ckIQTO4h8dY
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The type 2 diabetes drug dapagliflozin might also be used to help people with heart failure. A new study at Brigham and Women's Hospital showed that dapagliflozin – sold under the brand name Farxiga - reduced the risk of a cardiovascular death, or worsening heart failure, regardless of ejection fraction. Ejection fraction is a term that basically refers to how much blood is pumped out by the left ventricle of the heart each time it contracts. That’s important because this drug has already been shown to help people who have the reduced pumping. And that’s a lot more people. Big study here, more than 12-thousand people with lots of ages and races, benefits consistent throughout.
https://www.bostonglobe.com/2022/08/29/business/brigham-womens-researchers-say-diabetes-drug-helps-reduce-heart-failure/
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I hesitate to bring this study up, but it’s gotten a lot of attention this week. It shows tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease’s damaging effects on the brain. But this small study from Nemours Children’s Health, Jacksonville and Stanford University School of Medicine didn’t release any numbers, n other words, it’s not clear what they mean by tight control or at what level they’re referring to for brain issues. Their findings to indicate that automated hybrid closed loop systems work really well and that better glucose control can actually improve brain structure and function in teens with type 1. I’ve reached out to this group and we’re working on getting more information in a future episode.
https://neurosciencenews.com/blood-sugar-brain-diabetes-21328/
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Very early on here.. but an Indiana startup says they have a potentially game changing type 1 drug in development. In T1D, the body’s immune system causes destruction of beta cells, and as a result, they eventually stop producing insulin. These researchers say their models show thy can take what were thought to be dead beta cells, which are actually sleeping beta cells, and increase their insulin secretion and, basically, get them back to a functional state.” They’re focusing on a calcium imbalance within the beta cell and designing molecules to correct that calcium imbalance, ultimately returning the pancreas to a healthy state. JDRF has given them a big grant for a two year project, hopefully getting them to clinical trials.
https://www.insideindianabusiness.com/articles/startup-awarded-nearly-1m-to-advance-diabetes-drug
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People with type 2 diabetes might face a substantially increased risk of heart failure if they take ibuprofen or some other type of nonsteroidal anti-inflammatory drug (NSAID), accord to a new Danish study.
Short-term NSAID use increased risk of hospitalization for heart failure by 43% in people with type 2 but no previous heart problems. This was a large but preliminary study presented at the European Society of Cardiology's annual meeting. NSAIDs increased the risk of heart failure even more in type 2 diabetics who were 80 or older (78%) or who had high blood sugar levels (68%), the results showed. Those who'd never used an NSAID before had the worst reaction, with their heart failure risk nearly tripling. Type 2 diabetics should consult with their doctor before taking any pain medicine, the doctors said. Other types of pain meds -- specifically acetaminophen (Tylenol) -- should be safe for them to use.
https://www.usnews.com/news/health-news/articles/2022-08-24/certain-painkillers-raise-heart-failure-risk-in-people-with-type-2-diabetes

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Back to the news in a moment but first..
The T1D Exchange Registry is a research study conducted online over time, designed to foster innovation and improve the lives of people with T1D. The platform is open to both adults and children with T1D living in the U.S. Personal information remains confidential and participation is fully voluntary. Once enrolled, participants will complete annual surveys and have the opportunity to sign up for other studies on specific topics related to T1D. The registry aims to improve knowledge of T1D, accelerate the discovery and development of new treatments and technologies, and generate evidence to support policy or insurance changes that help the T1D community. By sharing opinions, experiences and data, patients can help advance meaningful T1D treatment, care and policy.
The registry is now available on the T1D Exchange website and is simple to navigate, mobile and user-friendly. For more information or to register, go to www.t1dregistry.org/stacey
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We told you about The Human Trial, Watch this gripping new documentary about the brave men and women who volunteer to test a radical new treatment for type 1 diabetes. n 2011, Lisa Hepner and her husband Guy Mossman heard about a radical stem cell treatment for diabetes, a disease that shockingly kills more than five million people each year. Driven by a desire to cure Lisa of her own type 1 diabetes (T1D), the filmmakers were given unprecedented, real-time access to a clinical trial — only the sixth-ever embryonic stem cell trial in the world. What follows is an intimate journey with the patients and scientists who put themselves on the line to be first.
Now, in partnership with Beyond Type 1 & JDRF , they’re offering the film for free. You are urged to make a donation to JDRF when you click over, there is an option to select zero,
https://watch.showandtell.film/watch/the-human-trial-beyond-type-1
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Next week we’ve got a great episode all about Omnipod 5 in the real world. I spoke to a panel of moms and a young adult using the system. And we’ve got Insulet’s Director of Medical affairs addressing the questions that come up. This past episode is with my son Benny, talking about what it was like to spend 8 weeks away at non diabetes camp without any remote monitoring from us.
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That’s In the News for this week.. if you like it, please share it! Thanks for joining me! See you back here soon.