Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚑 New studies on #OHCA: No significant survival benefit of intraosseous (IO) over IV access. IV remains the preferred route, with IO as backup. #EmergencyMedicine #CPR #CardiacArrest These 2 randomized clinical trials compared intraosseous (IO) vs. IV vascular access in out-of-hospital cardiac arrest (OHCA). The first study (Denmark) found no significant difference in return of spontaneous circulation (ROSC), 30-day survival, or neurological outcomes between IO and IV access.  The second study (UK) showed slightly higher ROSC in the IV-first group but no survival advantage. Both...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New study: Evolocumab shows strong CV benefits in older adults (≥75 yrs) with ASCVD! 📉 Lower LDL-C, reduced events (HR: 0.79, NNT: 19), & no major safety concerns. Time to rethink lipid guidelines for seniors? 🔬💙 #Cardiology #LipidLowering #Evolocumab

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

  Lipoprotein(a) [Lp(a)] is a genetically determined risk factor for atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Traditional lipid-lowering therapies have minimal impact on Lp(a), necessitating novel treatments. Zerlasiran, a small-interfering RNA (siRNA), significantly reduces Lp(a) (~85%) by inhibiting hepatic apolipoprotein(a) synthesis via subcutaneous injection. Muvalaplin, an oral small-molecule inhibitor, prevents Lp(a) particle formation, reducing levels by up to 85.8%. Both drugs were well-tolerated in Phase 2 trials, with further studies needed to...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

1. NEJM Article (2024): A 30-year study of 27,939 U.S. women found that high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) independently predicted cardiovascular risk. Higher levels of these biomarkers increased the risk of major cardiovascular events, emphasizing the need for early screening and prevention in women. 2. BrJSportsMed Article (2024): A study of 13,018 women found that even 1–3 minutes/day of vigorous intermittent lifestyle physical activity (VILPA) significantly reduced cardiovascular risk. Women engaging in 3.4 minutes/day had a 45% lower MACE risk and 67% lower heart...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

1. “Bioaccumulation of Microplastics in Decedent Human Brains” (Nature Medicine, 2024)   This study confirms the presence of microplastics and nanoplastics (MNPs) in human brain tissue, particularly the frontal cortex. Researchers used pyrolysis gas chromatography-mass spectrometry (Py-GC/MS) and electron microscopy to analyze postmortem samples, finding polyethylene (PE) as the dominant plastic type. Brain tissue exhibited significantly higher plastic concentrations than the liver or kidney, with even greater MNP accumulation in individuals diagnosed with dementia. The findings raise...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Kapila: Founder of Samkhya Philosophy Kapila (7th–6th century BCE) is regarded as the founder of the Samkhya school, one of the six orthodox systems of Hindu philosophy. Known for his rational and dualistic approach, he emphasized the distinction between Purusha (consciousness) and Prakriti (matter). His teachings are captured in the Samkhya Sutras and the Bhagavata Purana, where he elaborated on metaphysics, self-realization, and liberation from suffering. Kapila’s influence extends to Hinduism, Buddhism, and Jainism, making him a pivotal figure in ancient Indian philosophy.

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Coronary CT angiography-guided management of patients with stable chest pain: 10-year outcomes from the SCOT- HEART randomised controlled trial in Scotland Michelle C Williams, Ryan Wereski, Christopher Tuck, Philip D Adamson, Anoop S V Shah, Edwin J R van Beek, Giles Roditi, Colin Berry,Nicholas Boon, Marcus Flather, Steff Lewis, John Norrie, Adam D Timmis, Nicholas L Mills, Marc R Dweck, David E Newby, on behalf of theSCOT-HEART Investigators* Summary Background The Scottish Computed Tomography of the Heart (SCOT-HEART) trial demonstrated that management guided by coronary CT angiography...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Anaximander of Miletus (c. 610 – c. 546 BCE), a pre-Socratic philosopher and student of Thales, was a pioneer of cosmology, astronomy, and natural philosophy. He introduced the concept of the apeiron (infinite) as the origin of all things, developed early theories on evolution, and created one of the first world maps. His revolutionary ideas laid the groundwork for scientific thinking and inspired generations of philosophers and scientists.

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

 “The Protein Puzzle: Debunking Myths About Protein Deficiency in India”   This episode explores and debunks the myth of protein deficiency in India, highlighting that most Indians meet their protein needs through balanced diets.  It explains the Protein-to-Energy Ratio (PER) and how traditional food pairings like cereals and legumes enhance protein quality. Key insights include varying protein needs across age groups, the risks of overconsumption, and practical tips for improving dietary protein through affordable, accessible options.  The episode emphasizes that...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Gargi Vachaknavi, an esteemed philosopher and Vedic scholar of ancient India, is celebrated as one of the earliest female intellectuals in recorded history. Known for her profound knowledge of Brahma Vidya, she engaged in rigorous philosophical debates, including a renowned discourse with sage Yajnavalkya on the nature of existence and the ultimate reality. Revered as a Brahmavadini, Gargi contributed significantly to the intellectual and spiritual traditions of Vedic India, inspiring generations with her wisdom and critical thinking.