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Lower Blood Pressure, Sharper Minds, Less Dementia, Longer Lives ๐Ÿง ๐Ÿ’Š๐ŸŒพ show art Lower Blood Pressure, Sharper Minds, Less Dementia, Longer Lives ๐Ÿง ๐Ÿ’Š๐ŸŒพ

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿง  Big win for brains & blood pressure! In a massive rural China trial (n=33,995), lowering BP with non-physician care โ†“ dementia risk by 15%! A scalable, lifesaving model for LMICs. ๐ŸŒพ๐Ÿ’Š๐Ÿ“‰ #Dementia #Hypertension #GlobalHealth

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๐ŸŒฌ๏ธ Breathe Easy: Nasal Vaccines to the Rescue! show art ๐ŸŒฌ๏ธ Breathe Easy: Nasal Vaccines to the Rescue!

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿš€๐ŸŒฌ๏ธ Nasal vaccines: A breath of fresh air in respiratory infection prevention! ๐ŸŒŸ Boosts mucosal immunity (SIgA & IgG) ๐Ÿ’ช, reduces transmission ๐ŸŒก๏ธ, and protects against COVID-19, influenza, RSV, and more! #Vaccines #PublicHealth #Innovation ๐Ÿฆ ๐Ÿ’‰

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๐Ÿงฌ Silencing Risk: Lepodisiran vs Lp(a) show art ๐Ÿงฌ Silencing Risk: Lepodisiran vs Lp(a)

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿšจ New hope for high Lp(a)! ๐Ÿ’‰ Lepodisiran, a long-acting siRNA, slashed Lp(a) by 94% with just 2 shots/year. ๐Ÿ”ฌ RNA precision meets cardiac prevention. ๐Ÿ“‰ Silent killer, silenced. #CardioTwitter #RNAtherapy #LipoproteinA

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๐Ÿ’จ Breathing Battles: Navigating COPD Phenotypes show art ๐Ÿ’จ Breathing Battles: Navigating COPD Phenotypes

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐ŸŒฌ๏ธ๐Ÿšถโ€โ™‚๏ธ COPD comes in many forms! From chronic bronchitis ๐Ÿชซ to emphysema ๐Ÿ’จ, frequent exacerbators ๐Ÿšจ, asthma-COPD overlap ๐ŸŒช๏ธ, and eosinophilic type ๐Ÿงซ. Tailoring treatment to phenotype is key! #COPD #PrecisionMedicine #RespiratoryCare

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๐Ÿ’Š TANDEM Triumph: Dual Power for LDL Cholesterol Reduction! show art ๐Ÿ’Š TANDEM Triumph: Dual Power for LDL Cholesterol Reduction!

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿš€ TANDEM Trial: Combining Obicetrapib & Ezetimibe for a powerful LDL reduction! ๐Ÿ’Š โœ… -48.6% vs placebo, -27.9% vs Ezetimibe, -16.8% vs Obicetrapib ๐Ÿ’ช Safe, effective, and oral! #Cardiology #LipidManagement #ASCVD

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Fungal Pharmacists, Fatty Liver, Future Frontiers ๐Ÿงฌ๐Ÿฉธ๐Ÿ„ show art Fungal Pharmacists, Fatty Liver, Future Frontiers ๐Ÿงฌ๐Ÿฉธ๐Ÿ„

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

A gut fungus ๐Ÿ„ (Fusarium foetens) secretes FF-C1 ๐Ÿงช, a metabolite that inhibits CerS6 and lowers ceramides ๐Ÿฉธโ€”shielding mice from MASH ๐Ÿ›ก๏ธ. Fungi arenโ€™t just freeloadersโ€”they may be our next therapeutic allies! ๐Ÿ’Š๐Ÿง  #Microbiome #LiverHealth #FungalTherapy #Science

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๐Ÿ’ช Powerful Cholesterol Control: Obicetrapib in the Spotlight ๐ŸŒŸ show art ๐Ÿ’ช Powerful Cholesterol Control: Obicetrapib in the Spotlight ๐ŸŒŸ

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿš€ Obicetrapib: A Breakthrough in LDL Lowering! ๐Ÿ“‰ Reduced LDL by 29.9% in high-risk patients (p<0.001) ๐Ÿ’ก Promising adjunct to lipid-lowering therapy! #Cardiology #LipidManagement #HeartHealth ๐Ÿ’“

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Fat Chance! ๐Ÿ”ฌ๐Ÿงฌ Middle-Age Spread Starts at the Cellular Level show art Fat Chance! ๐Ÿ”ฌ๐Ÿงฌ Middle-Age Spread Starts at the Cellular Level

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Hereโ€™s a tweet with emojis based on the article:   ๐Ÿงฌ Middle-age spread decoded! ๐Ÿ•ฐ๏ธ Visceral fat grows in midlife not from bigger cellsโ€”but new ones! ๐ŸŽฏ CP-A cells fire up fat formation via LIFRโ€“STAT3 ๐Ÿ”ฅ ๐Ÿ’Š Targeting them may halt metabolic disease before it starts. #Aging #Obesity #CellBiology #Metabolism ๐Ÿงซ   Would you like a version with a more humorous tone or one tailored for clinicians?

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๐Ÿ”๐Ÿ“Š๐Ÿ›ก๏ธ Detect, Decode, Defend: A New Era in Coronary Risk Prediction show art ๐Ÿ”๐Ÿ“Š๐Ÿ›ก๏ธ Detect, Decode, Defend: A New Era in Coronary Risk Prediction

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿšจ New era in heart disease prediction! ๐Ÿงฌ + ๐Ÿงช + ๐Ÿค– = Meta-prediction model that beats PCE & QRISK3 ๐Ÿ“ˆ Detects hidden CAD risk in young, women & โ€œlow-riskโ€ groups ๐ŸŽฏ Precision prevention just got personal. ๐Ÿซ€ Published in Nature Medicine #CardioTwitter #AI #Genomics #CAD

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Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341โ€“270 BCE) โ€“ Founder of Epicureanism show art Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341โ€“270 BCE) โ€“ Founder of Epicureanism

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Epicurus (341โ€“270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain). His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.

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๐Ÿงฌ Your motherโ€™s X chromosome may shape how your brain ages.

In female mice, when only the maternal X chromosome (Xm) is active, older animals show worse memory ๐Ÿง ๐Ÿ•ณ๏ธ than those with random X-inactivation. This is due to imprinted genes โ€” some only expressed from the paternal X (Xp) โ€” which are silent when Xm dominates.

 

๐Ÿง ๐Ÿ’ก Using CRISPRโ€“Cas9, researchers reactivated 3 Xm-silent genes (Sash3, Tlr7, Cysltr1) and saw improved memory and mitochondrial function โšก๐Ÿ”‹.

 

๐Ÿ‘ฉโ€๐Ÿ”ฌ This highlights inter-female variation in aging and memory โ€” and suggests that epigenetic inheritance from mothers may shape how well we rememberโ€ฆ or forget. ๐Ÿง“๐Ÿง โ“