Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π§ Big win for brains & blood pressure! In a massive rural China trial (n=33,995), lowering BP with non-physician care β dementia risk by 15%! A scalable, lifesaving model for LMICs. πΎππ #Dementia #Hypertension #GlobalHealth
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
ππ¬οΈ Nasal vaccines: A breath of fresh air in respiratory infection prevention! π Boosts mucosal immunity (SIgA & IgG) πͺ, reduces transmission π‘οΈ, and protects against COVID-19, influenza, RSV, and more! #Vaccines #PublicHealth #Innovation π¦ π
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New hope for high Lp(a)! π Lepodisiran, a long-acting siRNA, slashed Lp(a) by 94% with just 2 shots/year. π¬ RNA precision meets cardiac prevention. π Silent killer, silenced. #CardioTwitter #RNAtherapy #LipoproteinA
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¬οΈπΆββοΈ COPD comes in many forms! From chronic bronchitis πͺ« to emphysema π¨, frequent exacerbators π¨, asthma-COPD overlap πͺοΈ, and eosinophilic type π§«. Tailoring treatment to phenotype is key! #COPD #PrecisionMedicine #RespiratoryCare
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
π TANDEM Trial: Combining Obicetrapib & Ezetimibe for a powerful LDL reduction! π β -48.6% vs placebo, -27.9% vs Ezetimibe, -16.8% vs Obicetrapib πͺ Safe, effective, and oral! #Cardiology #LipidManagement #ASCVD
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
A gut fungus π (Fusarium foetens) secretes FF-C1 π§ͺ, a metabolite that inhibits CerS6 and lowers ceramides π©Έβshielding mice from MASH π‘οΈ. Fungi arenβt just freeloadersβthey may be our next therapeutic allies! ππ§ #Microbiome #LiverHealth #FungalTherapy #Science
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
π Obicetrapib: A Breakthrough in LDL Lowering! π Reduced LDL by 29.9% in high-risk patients (p<0.001) π‘ Promising adjunct to lipid-lowering therapy! #Cardiology #LipidManagement #HeartHealth π
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Hereβs a tweet with emojis based on the article: 𧬠Middle-age spread decoded! π°οΈ Visceral fat grows in midlife not from bigger cellsβbut new ones! π― CP-A cells fire up fat formation via LIFRβSTAT3 π₯ π Targeting them may halt metabolic disease before it starts. #Aging #Obesity #CellBiology #Metabolism π§« Would you like a version with a more humorous tone or one tailored for clinicians?
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New era in heart disease prediction! 𧬠+ π§ͺ + π€ = Meta-prediction model that beats PCE & QRISK3 π Detects hidden CAD risk in young, women & βlow-riskβ groups π― Precision prevention just got personal. π« Published in Nature Medicine #CardioTwitter #AI #Genomics #CAD
info_outlineDr. Baliga's 'Got Knowledge Doc?' PODKASTS
Epicurus (341β270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain). His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.
info_outlineCancer cachexia isnβt just weight lossβitβs a hijacking of motivation π. Elevated IL-6 π₯ activates a brainstem-to-basal ganglia circuit π§ that suppresses dopamine π in the nucleus accumbens, leading to effort-based apathy π€.
Blocking IL-6 or boosting dopamine restores drive without changing weight, revealing a treatable neuroimmune pathway π‘.