π Ditch the Aspirin? π P2Y12 Prevails π‘οΈ After PCI
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New BMJ meta-analysis! After PCI & stopping DAPT, P2Y12 inhibitor monotherapy π reduces MACCE π§ β€οΈ (HR 0.77) vs aspirin β without more major bleeding π π« MI & stroke β π 16,117 pts, 5 trials π§ Smarter post-PCI strategy? #CardioTwitter #BMJ #PCI #P2Y12 #Aspirin π«
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π T Cells, TCF7, and Time β±οΈ: The Immune Key to Longevity: When transcription meets transformation
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
𧬠New study in Aging Cell finds immune resilienceβanchored by TCF7 expressionβconfers a π 15.5-year survival advantage! π₯ SAS-1 high / MAS-1 low = π to longevity π΅ Midlife is the window. π§ Age is biology, but resilience is destiny. #Longevity #Aging #Immunology #TCF7
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π« Hearts, Hope, and Health for All: Lancet Editorial
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π« Cardiovascular breakthroughs aboundβyet millions still die needlessly. π Innovation without equity is like a heart without a pulse. π‘ From molecules to communities, itβs time to turn science into survival. #GlobalHealth #CardioCare #EquityMatters
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Migraines: βProdrome, Precision, Prevention π«π§ πβ
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨New insights from the PRODROME trial! π Ubrogepant 100mg, given before the migraine hits, reduced photophobia, fatigue & brain fogβwithin hours! π§ Targets the prodrome, not just the pain. π A paradigm shift in migraine care? #Migraine #CGRP #NeuroTwitter N π https://doi.org/10.1038/s41591-025-03679-7
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Finerenone + Empagliflozin: Combo Wins π₯
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π Big win for kidneys! In the CONFIDENCE trial, combo therapy with #Finerenone + #Empagliflozin π slashed albuminuria 29β32% more than either alone in CKD + T2D patients π§ͺπ‘οΈ Safe, fast, and promising! π₯β±οΈβ #Nephrology #CardioRenal #SGLT2i #NEJM π§¬π©Ί
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Blindness, Breakthroughs, Biotech 𧬠From Darkness to Light via Nanoscience
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ποΈβ¨ Scientists have restored infrared vision using tellurium #nanowires implanted in the retina! π§ͺ Mice and primates regained light sensitivity and behavioral vision. π A bold leap toward restoring sight without bulky tech. #VisionScience #NeuroTech #Retina #Innovation
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π₯ Alcohol and π« Heart Disease: Dose, Debate, and Disease
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π· Is a glass of wine a heart helper or hidden hazard? The 2025 AHA Statement says: β οΈ Moderate = uncertain π« Heavy = harmful π« Risks include AFib, stroke, CAD, HF & sudden death π New genetic studies challenge old myths. π Know your limits. Rethink the drink. #CardioTwitter #MedEd #AHA2025
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Dr RR Baliga's Philosophical Discourses: Patanjali (India, c. 200 BCE) β Compiler of Yoga Sutras
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Patanjali, an ancient Indian sage, is credited with authoring foundational texts in Sanskrit grammar (MahΔbhΔαΉ£ya), yoga philosophy (Yoga Sutras), and possibly medicine (Patanjalatantra). Revered as a mystic and philosopher, his works laid the groundwork for classical yoga and linguistics, profoundly influencing Indian philosophical traditions. Though scholarly debates persist about his identity, Patanjali remains a significant figure in Hinduism, particularly in yoga and linguistic studies.
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π From Chemo to Cardio: Prescribing Steps, May Save Lives
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
πββοΈπͺ New NEJM study shows structured exercise after chemo boosts survival in colon cancer patients! π 5-yr DFS: 80.3% vs 73.9% β€οΈ 8-yr OS: 90.3% vs 83.2% 𧬠Fitness = longevity π Time to prescribe steps, not just scripts? #Oncology #ExerciseIsMedicine #CHALLENGEtrial
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SGLT2 inhibitors: Safer Teens, Stronger Kidneys, Steadier Glucose
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
π¨ New trial alert! In youth with type 1 diabetes, adding #SGLT2i π (dapagliflozin) to insulin: β Reduced glomerular hyperfiltration β Lowered HbA1c π β Boosted time-in-range β±οΈ π Safe with DKA precautions in place π #ATTEMPTTrial | @NatureMedicine π https://doi.org/10.1038/s41591-025-03723-6
info_outlineWhy do some people sleep just 4 hours and feel great? π΄πͺ
A new study links the 𧬠SIK3-N783Y mutation to natural short sleep!
Less sleep, more delta power π§ β‘
ππ
#SleepScience #Genetics #SIK3 #ShortSleepers