🔥 Age, Immune, Inflamming: Cracking the Code of Aging 🧬🛡️
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🔥 Immunosenescence + Inflammaging = Aging’s hidden engines. 🧬 New studies link immune decline to frailty, dementia, and disease. 🥗💉 Sleep, diet, vaccines, and GLP-1s may slow the clock. #Healthspan > #Lifespan 💡👴🛡️ Derived from Dr. Eric Topol’s Ground Truths on Substack.
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Beyond the Blockage: Arrhythmias, Aging, and Aortic Storms ⏳⚡🌀
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Heart attacks & strokes are down, but guess what’s rising? ⚡ Atrial fibrillation, 🫀 valve disease, & 🩸 VTE are taking the lead! It’s time to rethink prevention: from plaque to pulse to prognosis. 🧠💊📊 #CardioTwitter #HeartHealth #TheLancet https://doi.org/10.1016/S0140-6736(25)00990-0
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Fructose, Anxiety, Fear, and the Brain 🍭😨🧠
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🧠🍬 New study in Nature reveals: High-fructose exposure in early life impairs brain development by suppressing microglial phagocytosis via GLUT5 ➡️ HK2-driven metabolic rewiring. Result? 🐭 develop anxiety-like behavior. Cut the sweet talk. Think before you drink. #NeuroScience #FructoseFacts #MentalHealth 🧪🍼
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🏃♂️ Weight, Wellness, and the Weakening Heart
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨 New 2025 ACC Statement! Obesity worsens heart failure—but weight loss changes the game. 🏃♂️ Lifestyle helps. 💊 Semaglutide & tirzepatide show promise in HFpEF. 🔬 Rethink BMI. ⚖️ Precision + empathy = better outcomes. 👇 Dive into key takeaways. #CardioTwitter #Obesity #HeartFailure
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Forks, Frailty, and Forgetfulness 🦷➡️🧠: Mapping Malnutrition in Old Age
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👵🍽️ Malnutrition in aging isn’t just about food — it’s frailty, forgetfulness, and function. The DoMAP model 🧠🔺 reveals how low intake, high needs, and poor absorption collide with social, physical & mental challenges. Let’s fix the hidden hunger. 🥣❤️ #Geriatrics #Malnutrition #HealthyAging
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💊 Ditch the Aspirin? 🔄 P2Y12 Prevails 🛡️ After PCI
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🚨 New BMJ meta-analysis! After PCI & stopping DAPT, P2Y12 inhibitor monotherapy 💊 reduces MACCE 🧠❤️ (HR 0.77) vs aspirin — without more major bleeding 💉 🫀 MI & stroke ↓ 📊 16,117 pts, 5 trials 🧠 Smarter post-PCI strategy? #CardioTwitter #BMJ #PCI #P2Y12 #Aspirin 🚫
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💉 T Cells, TCF7, and Time ⏱️: The Immune Key to Longevity: When transcription meets transformation
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧬 New study in Aging Cell finds immune resilience—anchored by TCF7 expression—confers a 🚀 15.5-year survival advantage! 💥 SAS-1 high / MAS-1 low = 🔑 to longevity 👵 Midlife is the window. 🧠 Age is biology, but resilience is destiny. #Longevity #Aging #Immunology #TCF7
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🫀 Hearts, Hope, and Health for All: Lancet Editorial
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🫀 Cardiovascular breakthroughs abound—yet millions still die needlessly. 🌍 Innovation without equity is like a heart without a pulse. 💡 From molecules to communities, it’s time to turn science into survival. #GlobalHealth #CardioCare #EquityMatters
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Migraines: “Prodrome, Precision, Prevention 💫🧠💊”
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🚨New insights from the PRODROME trial! 💊 Ubrogepant 100mg, given before the migraine hits, reduced photophobia, fatigue & brain fog—within hours! 🧠 Targets the prodrome, not just the pain. 📈 A paradigm shift in migraine care? #Migraine #CGRP #NeuroTwitter N 🔗 https://doi.org/10.1038/s41591-025-03679-7
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Finerenone + Empagliflozin: Combo Wins 🥇
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💊 Big win for kidneys! In the CONFIDENCE trial, combo therapy with #Finerenone + #Empagliflozin 📉 slashed albuminuria 29–32% more than either alone in CKD + T2D patients 🧪🛡️ Safe, fast, and promising! 👥⏱️✅ #Nephrology #CardioRenal #SGLT2i #NEJM 🧬🩺
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Systemic Metabolic Disorder (SMD) gets a clinical staging makeover 🧬
From reversible risks 🌱 to systemic damage 🔥—this EAS consensus guides timely, targeted care 🎯
#MetabolicHealth #Cardiology #PrecisionMedicine #SMD 🩺📊