๐ง From Burst Cells to Blocked Organs: The New Vascular Story
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐งฌ New vascular villain? Itโs not always clots. ๐ฅ Necroptosis of endothelial cells triggers red blood cell rupture. ๐ฉธ Sticky RBC fragments form โendo-sealsโ that block blood flowโespecially in COVID-19, stroke, and MI. ๐ฏ Targets? Think MLKL & complement, not just platelets. #MedTwitter #COVID19 #VascularBiology #Pathology
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๐ก๏ธ Warriors, Watchers & Worn-Outs: Mapping Immune Identity
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐งฌ New study reveals 4 stable #Immunotypes in healthy adults! Each with unique ๐ฅinflammatory, ๐ฆ CMV-driven, ๐งquiet, or ๐ฅaging-linked immune traits. They predict LPS response better than age or sex. Welcome to the era of immune fingerprinting! ๐งช๐ง #PrecisionMedicine #Immunology #Multiomics
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Glycemic Wisdom: ๐ Spikes, Stats & Surprises
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ฅ Not all carbs are created equal โ or digested the same! A new study shows glycemic responses vary wildly by individual ๐๐ฅ๐๐ Your microbiome, metabolism, and ethnicity all matter! Precision nutrition is the future ๐ฌ๐งฌ๐ #GlycemicResponse #CGM #NutritionScience #T2D ๐ฝ๏ธ
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๐ง ๐ช๐งฌ Aging Redefined: Cracking the Epigenome with the "Intrinsic Capacity" Clock
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐งฌ A new epigenetic clock predicts your functional age โ not just birthdays! ๐ฐ๏ธ Built from 91 CpGs, the IC Clock outperforms GrimAge & others at predicting mortality ๐ช Linked to T-cell health, ๐ซ lung function & ๐ omega-3 intake ๐ Nature Aging: https://doi.org/10.1038/s43587-025-00883-5 #Aging #Epigenetics #Longevity #Immunosenescence Doximity
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๐ฏ Nuts About Health: Daily Dose, Daily Gains?
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ฅ Daily almonds = big wins for metabolic health! โ โ LDL & total cholesterol โ โ Vitamin E (ฮฑ-tocopherol) โ โ Gut inflammation (calprotectin, MPO) โ No change in systemic inflammation or weight Crunch wisely, live heart-smart! โค๏ธ๐ง #Nutrition #MetabolicSyndrome #RCT #Almonds #GutHealth
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๐งฌ Age, Clocks, and Plasma: The Biology of Rejuvenation
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐งช Can we turn back the clock? A new RCT shows TPE + IVIG reversed biological age by 2.6 years in older adults! ๐๐งฌ โ Boosted naรฏve T cells โ ๏ธ Small sample, no clinical endpoints ๐ Personalized markers predict response #Aging #LongevityScience #Epigenetics ๐ง๐โจ
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๐ Eat the Polyphenol Rainbow: Quantity + Variety = Longevity
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ฅ New study in Nature Food: Greater diversity of flavonoid intakeโnot just quantityโlinked to โ risk of death, diabetes, heart disease & more ๐๐๐ต Eat the rainbow daily: apples, tea, berries, citrus, greens = longevity boost ๐ช๐งฌ #Nutrition #Longevity #Flavonoids
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Dr RR Baliga's Philosophical Discourses: Marcus Aurelius (Rome, 121โ180 CE) โ Roman Emperor and Stoic Philosopher
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Marcus Aurelius (121โ180 CE), a Roman emperor and prominent Stoic philosopher, ruled from 161 to 180 CE. As the last of the Five Good Emperors, his reign marked the end of the Pax Romana, a period of relative peace in the Roman Empire. Known for his military campaigns against Parthians and Germanic tribes, he also endured the devastating Antonine Plague. His philosophical reflections, compiled in Meditations, offer insight into Stoic ethics and personal leadership. Marcus was succeeded by his son Commodus, whose rule marked a decline in Romeโs stability. His legacy endures in both...
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๐ฉธ Tiny Messengers, Big Damage: How RBC EVs Wreck Vascular Health in Diabetes
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
๐ฉธ New JCI study reveals how RBC-derived EVs ๐งฌ in #Type2Diabetes sneak into endothelial cells ๐งซ, delivering arginase-1 & sparking oxidative stress ๐ฅโa hidden cause of vascular dysfunction. Blocking EV uptake = ๐ก new therapy? ๐ https://doi.org/10.1172/JCI180900 #CardioTwitter #Diabetes #VascularBiology
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๐งญ From Prevention to Precision of Alzheimers Disease: New Frontiers
Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
Big shift in Alzheimerโs care! We can now predict it years in advance using ๐ฉธ biomarkers like p-tau217, ๐งฌ genetic risk, & ๐ค AI-analyzed retina scans. Prevention = lifestyle ๐ฅฆ๐โโ๏ธ๐ค, vaccines ๐, & maybe GLP-1s ๐. Why wait to treat when you can PREVENT? ๐ #Alzheimers #PrecisionMedicine #AI
info_outline๐จ๐ง BREAKING: Tenecteplase before thrombectomy boosts chances of stroke recovery!
๐ Faster reperfusion
๐ Higher functional independence (mRS 0โ2 at 90d: 52.9% vs 44.1%)
โ ๏ธ Slight โ in sICH, but no major safety red flags
๐งช #BRIDGE_TNK trial rewrites the stroke playbook!
#Stroke #Tenecteplase #NeuroTwitter