Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

New Study Alert! 🧠💉📉   Exciting real-world evidence shows that GLP-1 receptor agonists—semaglutide and tirzepatide—not only help with type 2 diabetes and obesity but may also reduce the risk of dementia, stroke, and all-cause mortality! 🙌📊   In a cohort of over 60,000 patients, these agents delivered neuroprotective and cerebrovascular benefits beyond glycemic control. Benefits were especially notable in older adults, women, and those with BMI 30–40. 💪👵🧬   🔗 If you’re passionate about brain health, diabetes, and the expanding therapeutic role...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🧬 New Insights into Gut–Heart Axis 🫀💡   Groundbreaking research published in Nature shows that Imidazole propionate (ImP)—a metabolite produced by gut bacteria—drives atherosclerosis by hijacking immune pathways in myeloid cells via the I1R–mTORC1 axis 🔥🧫.   📈 Elevated ImP levels predicted subclinical atherosclerosis independently of cholesterol in two large cohorts (PESA & IGT). 💊 Blocking this pathway with AGN192403 prevented plaque buildup—offering a novel, cholesterol-independent therapeutic target.   📚 Time to rethink cardiovascular...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Podcast Alert! 🎙️🧬   Curious about how modern medicine is tackling devastating mitochondrial DNA diseases like MELAS, LHON, and NARP? Our latest podcast dives into four landmark NEJM articles covering cutting-edge advances—from embryo screening (PGT) to groundbreaking mitochondrial replacement therapy (MRT). 🧪👶   Join us as we explore science, ethics, and hope at the frontier of germline medicine.⚖️💡   #MitochondrialMedicine #Genetics #PrecisionMedicine #ReproductiveHealth #NEJM #Podcast #PGT #PNT #Bioethics #ThreeParentBaby

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 AI meets ECG 🧠⚡ New insights show that a simple ECG — when powered by deep learning — can detect structural heart diseases like LV systolic dysfunction, HCM, and aortic stenosis with AUROCs >0.90! 🫀📈   📊 Sample size: 54,000+ | NPV >98% | p < 0.001 ✅ Low-cost, non-invasive, high-accuracy screening? Yes, please. 🧠 Time to rethink the ECG as a frontline diagnostic tool.   #Cardiology #ArtificialIntelligence #ECG #StructuralHeartDisease #DigitalHealth #MedTech #MachineLearning #HCM #LVSD #AorticStenosis #Innovation #PrecisionMedicine #HealthcareAI...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

New Podcast Episode Alert! 🎙️ “💧Block, Burst, or Both?💥 Understanding Male LUTS”   Up to 40% of men over 50 face lower urinary tract symptoms—from weak stream to nocturia. This week, we unpack the landmark JAMA 2025 review by Drs. Wei, Dauw, and Brodsky. 🧠💊   Tune in as we explore: 🔹 BPH vs Overactive Bladder 🔹 When to treat—and how 🔹 Meds, muscles, and minimally invasive magic 🔹 What every clinician should know before referring 🚑   🎧 Whether you’re a primary care doc, urologist, or just curious—this episode is worth the wait....

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚀 Just out in European Heart Journal! A novel AI model detects cardiac amyloidosis 🫀 using only a single apical 4-chamber echo clip 🎥🤖   Trained on a multiethnic, multisite cohort 🌍, this deep learning tool achieved AUROC 0.93—outperforming traditional risk scores like TCAS and IWT 📈💥   💡 Smarter screening, faster referrals, fewer missed diagnoses.   🔗 Read more and explore how AI is reshaping heart failure diagnostics👇 #Cardiology #AIinMedicine #Echocardiography #HeartFailure #DigitalHealth #PrecisionMedicine

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🧠✨ New Insights into Why We Sleep! ✨🛏️   Just read a groundbreaking study in Nature showing that leaky mitochondria in sleep-inducing neurons (dFBNs) drive the pressure to sleep! 😴🧬   Turns out, electron overflow and oxidative stress during wakefulness aren’t just metabolic side effects—they’re biological signals telling the brain it’s time to rest. 🔋➡️💥➡️🛌   Mitochondrial fission decreases sleep, fusion promotes it, and sleep literally resets neuronal metabolism.   A must-read for anyone interested in neuroscience, metabolism, or...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Insights on Heart Attack Risk! 🧬❤️   A must-read from Circulation: Genomic and Precision Medicine—Bhattacharya et al. show that Polygenic Risk Score (PRS) rivals traditional giants like hypertension in predicting MI! 💥   📊 With an R² loss of 12.4% and PAR of 38.4%, PRS isn’t just academic—it’s actionable. Add in hsCRP and Lp(a), and we’re entering a new era of CAD risk stratification.   🔍 From base to full model: ➡️ R²: 0.021 → 0.053 ➡️ C-statistic: 0.65 → 0.73 ➡️ PAR: 84.3%   Let’s embrace the fusion of clinical +...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Research Alert! 💡 Just explored a fascinating preclinical study on apigenin 🧪—a flavonoid found in parsley & chamomile 🌿—that prevents muscle loss in aging, obese rats 🐀💪.   📉 While it didn’t stop weight gain or fat buildup, apigenin boosted muscle mass, reduced fibrosis 🦵, and activated anabolic signaling (p70S6K) 🔁.   💊 Could this be a future nutraceutical for sarcopenic obesity and healthy aging? More clinical research needed—but the signal is strong. 🚦   #Apigenin #Flavonoids #Sarcopenia #Obesity #MuscleHealth #Aging...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New in 2025! The ACC/AHA Appropriate Use Criteria for ICDs, CRT, and Pacing just got a major upgrade! 🫀📊 Covering 335 real-world scenarios, this document is your go-to guide for when (and when not) to implant. 💡   What’s 🔥 in the update? ⚡ Leadless & conduction system pacing 🔁 CRT refined for better outcomes 🧠 Smart use in LVADs, post-transplant, & more   👩‍⚕️ Clinicians: Make device decisions with clarity, confidence, and evidence. 📥 Download our podcast + slides to stay ahead.   #Cardiology #ICD #CRT #Pacing #AUC #HeartFailure #EP...