Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚀 Just out in European Heart Journal! A novel AI model detects cardiac amyloidosis 🫀 using only a single apical 4-chamber echo clip 🎥🤖   Trained on a multiethnic, multisite cohort 🌍, this deep learning tool achieved AUROC 0.93—outperforming traditional risk scores like TCAS and IWT 📈💥   💡 Smarter screening, faster referrals, fewer missed diagnoses.   🔗 Read more and explore how AI is reshaping heart failure diagnostics👇 #Cardiology #AIinMedicine #Echocardiography #HeartFailure #DigitalHealth #PrecisionMedicine

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🧠✨ New Insights into Why We Sleep! ✨🛏️   Just read a groundbreaking study in Nature showing that leaky mitochondria in sleep-inducing neurons (dFBNs) drive the pressure to sleep! 😴🧬   Turns out, electron overflow and oxidative stress during wakefulness aren’t just metabolic side effects—they’re biological signals telling the brain it’s time to rest. 🔋➡️💥➡️🛌   Mitochondrial fission decreases sleep, fusion promotes it, and sleep literally resets neuronal metabolism.   A must-read for anyone interested in neuroscience, metabolism, or...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Insights on Heart Attack Risk! 🧬❤️   A must-read from Circulation: Genomic and Precision Medicine—Bhattacharya et al. show that Polygenic Risk Score (PRS) rivals traditional giants like hypertension in predicting MI! 💥   📊 With an R² loss of 12.4% and PAR of 38.4%, PRS isn’t just academic—it’s actionable. Add in hsCRP and Lp(a), and we’re entering a new era of CAD risk stratification.   🔍 From base to full model: ➡️ R²: 0.021 → 0.053 ➡️ C-statistic: 0.65 → 0.73 ➡️ PAR: 84.3%   Let’s embrace the fusion of clinical +...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Research Alert! 💡 Just explored a fascinating preclinical study on apigenin 🧪—a flavonoid found in parsley & chamomile 🌿—that prevents muscle loss in aging, obese rats 🐀💪.   📉 While it didn’t stop weight gain or fat buildup, apigenin boosted muscle mass, reduced fibrosis 🦵, and activated anabolic signaling (p70S6K) 🔁.   💊 Could this be a future nutraceutical for sarcopenic obesity and healthy aging? More clinical research needed—but the signal is strong. 🚦   #Apigenin #Flavonoids #Sarcopenia #Obesity #MuscleHealth #Aging...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New in 2025! The ACC/AHA Appropriate Use Criteria for ICDs, CRT, and Pacing just got a major upgrade! 🫀📊 Covering 335 real-world scenarios, this document is your go-to guide for when (and when not) to implant. 💡   What’s 🔥 in the update? ⚡ Leadless & conduction system pacing 🔁 CRT refined for better outcomes 🧠 Smart use in LVADs, post-transplant, & more   👩‍⚕️ Clinicians: Make device decisions with clarity, confidence, and evidence. 📥 Download our podcast + slides to stay ahead.   #Cardiology #ICD #CRT #Pacing #AUC #HeartFailure #EP...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🧘‍♂️📿 Discover the timeless wisdom of Adi Shankaracharya (788–820 CE) — the master of Advaita Vedanta who redefined spirituality with concepts like Atman, Brahman & Sanyasa. His teachings on non-duality still inspire seekers worldwide. 🌍📚 #Philosophy #Vedanta #Spirituality

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🫀 New insights from Covani et al. and Ben-Yehuda’s editorial reveal a striking paradox: more cardiovascular risk factors 🔥 = more plaque rupture, but less erosion! 🧊   Using OCT imaging, they show how traditional risks drive inflammatory, rupture-prone plaques, while erosion may follow a different path altogether—less lipid, less inflammation, more mystery. 🧬   🎯 Takeaway: Precision prevention must evolve. Not all plaques (or patients) follow the same script.   🔗 Dive into this convergence of epidemiology & imaging 👉 #PlaqueVulnerability #STEMI...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🌍🔬 What’s shaping your health beyond your genes?   Introducing our latest Got Knowledge Doc podcast episode: “Beyond Genes, Beneath the Skin 🧬🌫️” — a deep dive into the exposome, the totality of your environmental exposures from womb to tomb.   From microplastics to sleep, PFAS to social stress, we’re mapping the missing link in precision medicine. 🎧 Tune in to explore why the future of health might depend less on your DNA and more on your data trail.   🧠 Prevention. 📊 Policy. 💊 Personalization.   #Exposome #PrecisionMedicine...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🚨 New Insights in Hypertrophic Cardiomyopathy (HCM)! 💓 Groundbreaking research shows that regulatory T cells (TREGs) can reduce fibrosis, suppress inflammation, and even improve heart function in HCM 🧬🛡️   From adoptive TREG transfer to IL-2 therapy, immunomodulation is emerging as a promising strategy alongside genetic and myosin-targeted treatments 💉📉   🧠 A must-read for cardiologists, immunologists & translational researchers! 📄 Wang et al., Sci. Transl. Med. 2025 🔗 #Cardiology #HCM #TREG #Immunotherapy #Fibrosis #PrecisionMedicine...

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

🧠💤 Just dropped our latest Got Knowledge Doc podcast: “Flush, Sleep, Forget: The Glymphatic Code in Alzheimer’s Disease” 🧬🎧   We explore how the brain’s nighttime rinse cycle clears toxic proteins like amyloid β and tau—and what happens when that system breaks down. From rodent models to human MRI, it’s a story of sleep, science, and hope. 🌙🔬   Listen in to learn how advancing glymphatic research might open doors to early detection and prevention of Alzheimer’s. 🧪🧩   #AlzheimersDisease #GlymphaticSystem #Neuroscience #SleepScience...