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Exercise Without Exercise? Betaineโ€™s Magic Revealed! ๐Ÿง˜โœจ๐Ÿงฌโ€ show art Exercise Without Exercise? Betaineโ€™s Magic Revealed! ๐Ÿง˜โœจ๐Ÿงฌโ€

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿ’ก New Study Alert! ๐Ÿƒโ€โ™‚๏ธ๐Ÿงช Kidney-derived betaine mimics long-term exerciseโ€”blocking TBK1, reducing inflammation, and reversing aging markers. This multi-omics human + mouse study uncovers betaine as a precision geroprotector for those who canโ€™t hit the gym.   ๐Ÿ“ˆ A leap toward exercise mimetics in aging science! #Geroprotection #PrecisionMedicine #ExerciseScience #Betaine ๐Ÿงฌ๐Ÿง“๐Ÿ”ฅ

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๐Ÿงช Reset, Rewind, Rejuvenate: Chemical Reprogramming Against Aging show art ๐Ÿงช Reset, Rewind, Rejuvenate: Chemical Reprogramming Against Aging

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿงฌ Rewinding Cellular Time with Chemistry! ๐Ÿงช A groundbreaking study just showed that a two-chemical cocktail (2c) โ€” Tranylcypromine + Repsox โ€” can reverse aging markers in human cells and extend C. elegans lifespan by 42%! ๐Ÿ›๐Ÿ’ฅ   Unlike gene-based reprogramming, this method is safer, scalable, and preserves cell identity. Think of it as โ€œYamanaka liteโ€ โ€” with big implications for aging and longevity science. ๐Ÿง ๐Ÿ’Š   #Longevity #Epigenetics #Rejuvenation #Biotech #AgingResearch #Lifespan

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From ABI to Amputation: Navigating PAD with Precision show art From ABI to Amputation: Navigating PAD with Precision

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿšถโ€โ™‚๏ธ๐Ÿ’” Just recorded a podcast on Peripheral Artery Disease (PAD) โ€“ a silent threat affecting 200M+ people worldwide.   We unpack the latest 2024 ACC/AHA guidelines: โœ… When to screen ๐Ÿ’Š What therapies work ๐Ÿฆฟ How to save limbs & lives   Tune in to walk away smarter. ๐Ÿ‘ฃ๐ŸŽ™๏ธ #PAD #Cardiology #Guidelines #Prevention #LimbSalvage

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Osteoporosis Uncovered: Risk, Resilience, and Recovery ๐Ÿ”๐Ÿ›ก๏ธ๐Ÿ”„ show art Osteoporosis Uncovered: Risk, Resilience, and Recovery ๐Ÿ”๐Ÿ›ก๏ธ๐Ÿ”„

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Just finished reviewing the latest JAMA 2025 article on osteoporosis by Morin et al. โ€” a must-read for anyone managing bone health in aging adults!   ๐Ÿ“‰ Despite advances, 70% of fractures occur in those without DXA-defined osteoporosis. ๐Ÿ’Š Treatment isnโ€™t just about T-scores โ€” itโ€™s about fracture risk, fall prevention, and smart sequencing of antiresorptive and anabolic therapies. ๐Ÿ‹๏ธโ€โ™€๏ธ Plus, lifestyle matters: resistance training, calcium, vitamin D, and proactive screening save lives.   ๐Ÿ“ˆ Fracture Liaison Services (FLS) boost treatment initiation from 17%...

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๐Ÿงฌ Targeting Aldosterone: A New Shot at Hypertension ๐ŸŽฏ๐Ÿ’ฅ show art ๐Ÿงฌ Targeting Aldosterone: A New Shot at Hypertension ๐ŸŽฏ๐Ÿ’ฅ

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿšจ New breakthrough in hypertension care!   ๐Ÿ’Š The Launch-HTN trial shows lorundrostat โ€” a selective aldosterone synthase inhibitor โ€” significantly lowers systolic BP in patients with uncontrolled or treatment-resistant hypertension.   ๐Ÿ“‰ โˆ’16.9 mmHg vs โˆ’7.9 mmHg with placebo (P < .001) ๐Ÿงช Safe, well-tolerated, and effective across subgroups.   A potential game-changer in aldosterone-targeted therapy! ๐Ÿ”„๐Ÿ’ฅ #Hypertension #Cardiology #ClinicalTrials #PrecisionMedicine

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Diagnose, Personalize, Optimize: The 2025 Diabetes Blueprint show art Diagnose, Personalize, Optimize: The 2025 Diabetes Blueprint

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Our latest podcast episode unpacks the 2025 JAMA Review on Type 2 Diabetes ๐Ÿ”ฌ๐Ÿ’Š   We explore: โœ… New diagnostic strategies โœ… Why GLP-1s & SGLT2is are game-changers โœ… How lifestyle change can lead to remission โœ… Individualizing A1C goals in real-world care   ๐ŸŽ™๏ธ Episode Title: โ€œDiagnose, Personalize, Optimize: The 2025 Diabetes Blueprintโ€ ๐Ÿ“ˆ Essential listening for clinicians, educators, and innovators in endocrine & cardiometabolic care.   ๐Ÿ‘‰ Tune in now and share with your network! #Type2Diabetes #CardiometabolicCare #GLP1 #SGLT2...

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Early to Bed, Stronger Steps Ahead ๐Ÿ’ค๐Ÿ’ช๐Ÿ‘ฃโ€ show art Early to Bed, Stronger Steps Ahead ๐Ÿ’ค๐Ÿ’ช๐Ÿ‘ฃโ€

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

How we sleep tonight shapes how we move tomorrow! ๐Ÿ“‰๐Ÿƒโ€โ™‚๏ธ In a large-scale wearable study (๐Ÿ“ฑWHOOP & Fitbit data from >25,000 adults), researchers found: โœ… Sleeping earlier than usual boosts next-day physical activity โŒ Longer or later sleep = less movement ๐Ÿ”ฅ Max gains came from consistent sleep duration + early bedtime Letโ€™s rethink our ๐Ÿ’ค to power our ๐Ÿ’ฅ! ๐Ÿ“ฃ Public health campaigns should promote sleep and exercise togetherโ€”not in competition.   ๐Ÿ“„ PNAS, June 2025 | doi:   #SleepHealth #PhysicalActivity #WearableTech #Chronobiology...

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Wrinkle, Rust, and Rewind: 17 Theories of Why We Age show art Wrinkle, Rust, and Rewind: 17 Theories of Why We Age

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿงฌ Curious why we age? ๐Ÿ•ฐ๏ธ From DNA damage to developmental programs gone rogue, this new podcast episode dives deep into 17 theories of ageing โ€” some classic, some controversial.   ๐Ÿ” We explore wear-and-tear, free radicals, telomeres, mitochondria, stem cell exhaustion, and the rising stars of epigenetic drift and hyperfunction theory.   ๐ŸŽ™๏ธ Whether youโ€™re a scientist, clinician, or just fascinated by the biology of time, tune in to uncover what really drives the ageing processโ€”and what might one day slow it down.   ๐Ÿง  Listen now: โ€œWrinkle, Rust, and...

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๐Ÿ’ฅ Beyond the Block: Cracking the Code of Chest Pain ๐Ÿ”ฌโค๏ธ show art ๐Ÿ’ฅ Beyond the Block: Cracking the Code of Chest Pain ๐Ÿ”ฌโค๏ธ

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

Refractory Angina: Time to Rethink the Diagnosis ๐Ÿซ€๐Ÿ’ฅ   Chest pain that defies stents and statins? It may not be your typical obstructive CAD. This podcast unpacks the redefinition of refractory angina โ€” spotlighting INOCA, CMD, vasospasm, and myocardial bridging ๐Ÿ”ฌโš™๏ธ We explore PET, CMR, CFVR, and wire-based diagnostics ๐Ÿ”Ž โ€” and why a multidisciplinary Angina Heart Team is key to transforming care ๐Ÿ‘ฉโ€โš•๏ธ๐Ÿ‘จโ€โš•๏ธ๐Ÿง  ๐ŸŽง Listen in as we chart a course from frustration to precision โ€” because even stubborn angina has a story and a solution.  ...

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Inflammaging: Myth, Marker, or Mismatch? ๐Ÿงชโ“๐ŸŒ show art Inflammaging: Myth, Marker, or Mismatch? ๐Ÿงชโ“๐ŸŒ

Dr. Baliga's 'Got Knowledge Doc?' PODKASTS

๐Ÿ”ฌ๐ŸŒ New insights from Nature Aging: Inflammaging isnโ€™t universal!   A fascinating cross-cultural study comparing Italy ๐Ÿ‡ฎ๐Ÿ‡น, Singapore ๐Ÿ‡ธ๐Ÿ‡ฌ, Bolivia ๐Ÿ‡ง๐Ÿ‡ด, and Malaysia ๐Ÿ‡ฒ๐Ÿ‡พ shows that age-related inflammationโ€”long considered a hallmark of agingโ€”may actually be a product of industrialized environments.   Populations like the Tsimane (Bolivia) and Orang Asli (Malaysian), despite high infection loads, show minimal correlation between cytokines and age-related disease.   ๐Ÿ“‰ Conclusion: Inflammaging is not destinyโ€”itโ€™s context.   ๐Ÿงช Read the...

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More Episodes

๐Ÿงฌ Rewinding Cellular Time with Chemistry! ๐Ÿงช

A groundbreaking study just showed that a two-chemical cocktail (2c) โ€” Tranylcypromine + Repsox โ€” can reverse aging markers in human cells and extend C. elegans lifespan by 42%! ๐Ÿ›๐Ÿ’ฅ

 

Unlike gene-based reprogramming, this method is safer, scalable, and preserves cell identity. Think of it as โ€œYamanaka liteโ€ โ€” with big implications for aging and longevity science. ๐Ÿง ๐Ÿ’Š

 

#Longevity #Epigenetics #Rejuvenation #Biotech #AgingResearch #Lifespan