Dr. Baliga's 'Got Knowledge Doc?' PODKASTS
🧠✨ Just read a thought-provoking article in JAMA on the US POINTER trial! Structured lifestyle changes (think 🏃♀️🥗🧩) showed modest but real gains in cognition for older adults at risk of dementia. But here’s the twist: even light-touch self-guided changes yielded nearly similar benefits. 🤯 So… 💬 Is intensity always worth the investment? Or can simplicity scale smarter? 🔗 Worth pondering as we shape the future of brain health! #DementiaPrevention #CognitiveHealth #LifestyleMedicine #PublicHealth #BrainAging 🧠📈
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🔬 New Review Alert! 🫀 South Asians face one of the highest global burdens of premature heart disease — and Lp(a) may be the silent culprit. 📈 In a comprehensive JAHA 2025 review, researchers reveal how 25% of South Asians have dangerously elevated Lp(a) levels, doubling their risk of myocardial infarction. 🧬💥 Key takeaways: ✅ Lp(a) is genetically driven & unaffected by lifestyle ✅ Risk is underestimated by standard calculators ✅ Novel therapies (PCSK9i, siRNA, ASOs) are on the horizon ✅ One-time testing is now strongly recommended in all South Asians...
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📢 New insights on education & brain aging! 🧠📉 A mega-analysis across 33 countries (170K+ participants, 15K+ MRIs) shows 📚 higher education boosts baseline memory—but doesn’t slow brain aging or cognitive decline over time. ❌🧓 ✅ Early-life traits (like childhood cognition & environment) drive the advantage. 🔗 Education matters—but not in the way we thought. Full story: “Reevaluating the role of education on cognitive decline and brain aging” in Nature Medicine 🧬🌍 #CognitiveHealth #BrainAging #LifelongLearning...
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🧬 Just dropped: our latest podcast episode 🎙️ dives into Lipoprotein(a) and its powerful role in predicting vascular disease beyond the heart 🫀—including PAD 🦵 and stroke 🧠. 📊 Based on a massive UK Biobank study (n=460K+), high Lp(a) levels (≥150 nmol/L) were linked to: • 18% ↑ risk of PAD • 17% ↑ risk of carotid stenosis • 60% ↑ risk of major limb events ⚠️ Lp(a) is more than a lab value—it’s a Vascular Crystal Ball. #LipoproteinA #PAD #Stroke #VascularMedicine #PrecisionCardiology #CardioPodcast #Biomarkers #Atherosclerosis...
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🧠✨ Dive into the mind of Avicenna (Ibn Sina) — the Persian polymath who shaped medicine, metaphysics, and logic for centuries. From the Canon of Medicine to the Book of Healing, his legacy lives on in modern science and thought. 🎓📚 #Philosophy #Medicine #Avicenna
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📢 New Data Drop! 🫀💥 South Asian adults in the U.S. have an earlier and sharper rise in coronary artery calcium (CAC) — a silent marker of heart disease risk! 🇮🇳📊 In a first-of-its-kind study combining MASALA & DILWALE cohorts (n=2,743), 65% of South Asian men and 30% of women had CAC >0 by age 55 — and women catch up fast after menopause. 🚹➡️🚺 📌 Sex-specific CAC percentiles = smarter screening, better prevention. 💡 Time to rethink traditional risk calculators for this high-risk group. 🎙️ Podcast title: “Men First, Women...
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🚨 New Insights from Nature Medicine 🧠🍕 Can cookies and chips hijack your brain like cocaine? A compelling new article argues that ultra-processed food addiction mirrors classic substance use disorders — down to the cravings, compulsive use, and reward circuit disruption. With GLP-1 drugs bridging obesity and addiction treatment, is it time the DSM-5 recognized food addiction? 🧬 Science says yes. ⚖️ Policy is lagging. 📢 Let’s start the conversation. #FoodAddiction #UltraProcessedFoods #DSM5 #GLP1 #PublicHealth #Neuroscience #Obesity #HealthPolicy...
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🚨 New Hypertension Guidance Alert! 🩺💡 The British & Irish Hypertension Society now recommends treating all adults with sustained BP ≥135/85 mmHg—regardless of CVD risk—and targeting <130/80 mmHg within 6 months. No more waiting for risk scores to rise 📉⏳. This bold, evidence-backed move aligns with global trends 🌍 and aims to end therapeutic inertia for good. Let’s make treatment simpler, safer, and sooner! 💊✅ #Hypertension #Guidelines #PrimaryCare #Cardiology #PublicHealth
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🧠🏃♂️ Can running rewire the Alzheimer’s brain? New study in Nature Neuroscience shows how exercise transforms cell-specific gene expression in the dentate gyrus of AD mice! Using single-nucleus RNA-seq, researchers found that voluntary running reversed transcriptional dysregulation in key cell types—especially immature neurons, astrocytes, and microglia. 💡Highlights: ✅ Neurogenesis boosted ✅ Disease-associated microglia reprogrammed ✅ Novel astrocyte subpopulation rescued This could pave the way for targeted therapeutics rooted in the biology of...
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🚨 Statins & Diabetes: Dose Matters, But So Does Perspective 💊📉 A 2024 CTT Collaboration meta-analysis of 154,664 participants confirms: ✅ Statins modestly increase risk of diabetes (10% with moderate, 36% with high-intensity) 📈 Small upticks in HbA1c and glucose 🧪 But most new cases were already teetering near the threshold 🩺 Bottom line? Cardiovascular benefits far outweigh the diabetes risk. 💡 It’s a reminder: precision prevention is about balancing risk, not eliminating it. 📚 Ref: Lancet Diabetes Endocrinol 2024 | DOI: #Statins #Diabetes...
info_outline🌍🔬 What’s shaping your health beyond your genes?
Introducing our latest Got Knowledge Doc podcast episode: “Beyond Genes, Beneath the Skin 🧬🌫️” — a deep dive into the exposome, the totality of your environmental exposures from womb to tomb.
From microplastics to sleep, PFAS to social stress, we’re mapping the missing link in precision medicine.
🎧 Tune in to explore why the future of health might depend less on your DNA and more on your data trail.
🧠 Prevention. 📊 Policy. 💊 Personalization.
#Exposome #PrecisionMedicine #EnvironmentalHealth #PublicHealth #WearableTech #GotKnowledgeDoc