Addressing Extracellular Matrix Breakdown That Leads to Age-Related Diseases with Dr. Sherif Idriss Elastin Biosciences TRANSCRIPT
Release Date: 09/24/2024
Real-Time Clinical Artificial Intelligence Drives Precision Care with Dr. David Kirk Regard TRANSCRIPT
Empowered Patient Podcast
Dr. David Kirk, Chief Medical Officer at Regard, discusses the role and benefits of real-time clinical AI to help clinicians navigate patient charts and find critical information to prevent medication management errors and misdiagnoses. The Regard platform can also generate proactive documentation, allowing physicians to complete their documentation more accurately and efficiently, reducing note-bloat and the need for after-hours charting. One key goal of using AI is to free physicians to spend more time on the art of medicine, directly working with patients. David explains, "So,...
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Real-Time Clinical Artificial Intelligence Drives Precision Care with Dr. David Kirk Regard
Empowered Patient Podcast
Dr. David Kirk, Chief Medical Officer at Regard, discusses the role and benefits of real-time clinical AI to help clinicians navigate patient charts and find critical information to prevent medication management errors and misdiagnoses. The Regard platform can also generate proactive documentation, allowing physicians to complete their documentation more accurately and efficiently, reducing note-bloat and the need for after-hours charting. One key goal of using AI is to free physicians to spend more time on the art of medicine, directly working with patients. David explains, "So,...
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Data Analytics Platform Improves Patient Safety and Hospital Performance with Daniel Hart Sentact TRANSCRIPT
Empowered Patient Podcast
Daniel Hart, CEO of Sentact, describes the need to integrate technology, analytics, and services for hospitals and health systems to improve patient safety, patient outcomes, and regulatory readiness. One of Sentact's key goals is to help organizations gain insights from data to allow them to move from a reactive posture using lagging indicators to a proactive environment supported by AI and real-time data to generate early warning signals. Successful implementation of these insights also reduces operational costs and potentially eases clinician burnout. Daniel explains, "Sentact is a...
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Data Analytics Platform Improves Patient Safety and Hospital Performance with Daniel Hart Sentact
Empowered Patient Podcast
Daniel Hart, CEO of Sentact, describes the need to integrate technology, analytics, and services for hospitals and health systems to improve patient safety, patient outcomes, and regulatory readiness. One of Sentact's key goals is to help organizations gain insights from data to allow them to move from a reactive posture using lagging indicators to a proactive environment supported by AI and real-time data to generate early warning signals. Successful implementation of these insights also reduces operational costs and potentially eases clinician burnout. Daniel explains, "Sentact is a...
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Continuing Healthcare Professional Education Undergoes AI Transformation with Matt Holland Healio TRANSCRIPT
Empowered Patient Podcast
Matt Holland is Chief Operating Officer at Healio, a company that has been producing high-quality, vetted information for healthcare professionals for over 100 years. The company has focused on personalization of data as it has evolved from print to digital to AI-driven access to on-demand information. Healio AI is also transforming continuing medical education from a static activity to a dynamic, personalized experience based on real-time information gaps. Matt explains, "We're a little bit unique in this space. We're family-owned and privately held, and have been for over a hundred...
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Continuing Healthcare Professional Education Undergoes AI Transformation with Matt Holland Healio
Empowered Patient Podcast
Matt Holland is Chief Operating Officer at Healio, a company that has been producing high-quality, vetted information for healthcare professionals for over 100 years. The company has focused on personalization of data as it has evolved from print to digital to AI-driven access to on-demand information. Healio AI is also transforming continuing medical education from a static activity to a dynamic, personalized experience based on real-time information gaps. Matt explains, "We're a little bit unique in this space. We're family-owned and privately held, and have been for over a hundred...
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Driving Innovation in Cell Therapy Manufacturing with Ryan Clarke Syntax Bio TRANSCRIPT
Empowered Patient Podcast
Ryan Clarke, Co-Founder and CTO of Syntax Bio, is focused on solving manufacturing challenges in producing stem cell-derived therapies, specifically the process of stem cell differentiation. The Cellgorithm platform was designed to make differentiation an engineering problem by using a modified form of CRISPR to turn genes on and off in a specific, controlled sequence, reducing processing time from months to days and resulting in cost savings. One goal is to use AI and machine learning to build models capable of predicting optimal gene regulation sequences accelerating the discovery of...
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Driving Innovation in Cell Therapy Manufacturing with Ryan Clarke Syntax Bio
Empowered Patient Podcast
Ryan Clarke, Co-Founder and CTO of Syntax Bio, is focused on solving manufacturing challenges in producing stem cell-derived therapies, specifically the process of stem cell differentiation. The Cellgorithm platform was designed to make differentiation an engineering problem by using a modified form of CRISPR to turn genes on and off in a specific, controlled sequence, reducing processing time from months to days and resulting in cost savings. One goal is to use AI and machine learning to build models capable of predicting optimal gene regulation sequences accelerating the discovery of...
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Origins and Future of Medical Imaging with Dr. Daniel Sodickson Function Health TRANSCRIPT
Empowered Patient Podcast
Dr. Daniel Sodickson is Chief Medical Scientist at Function Health and author of the new book, The Future of Seeing: How Imaging Is Changing Our World. Building on the drive to improve medical imaging, AI and neural networks are now reshaping image interpretation and how and what data are collected. This approach produces high-quality results with minimal additional data and is inspiring innovative scanning techniques and equipment design. The future of medical imaging is the everywhere scanner, enhancing a single-shot session with a large hospital machine with continuous health...
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Origins and Future of Medical Imaging with Dr. Daniel Sodickson Function Health
Empowered Patient Podcast
Dr. Daniel Sodickson is Chief Medical Scientist at Function Health and author of the new book, The Future of Seeing: How Imaging Is Changing Our World. Building on the drive to improve medical imaging, AI and neural networks are now reshaping image interpretation and how and what data are collected. This approach produces high-quality results with minimal additional data and is inspiring innovative scanning techniques and equipment design. The future of medical imaging is the everywhere scanner, enhancing a single-shot session with a large hospital machine with continuous health...
info_outlineDr. Sherif Idriss is the CEO of Elastin Biosciences, a company focused on targeting aging-related diseases by restoring elastin, a key protein in the extracellular matrix that provides elasticity and resilience to organs and tissues. They are developing small molecule therapies for diseases linked to elastin deficiency, including Williams syndrome and abdominal aortic aneurysm. As elastin degrades over time due to aging, it leads to loss of tissue structural integrity and function, contributing to numerous age-related diseases.
Sherif explains, "One of the hallmarks of aging is the loss of the extracellular matrix, which is composed of several proteins. Collagen is quite famous, but also elastin is the other major protein that is responsible for the elasticity of the different organs. For example, in our skin, the loss of elastin is associated with us looking older and having all the aging signs and wrinkles on the skin. If you imagine that there are other organs inside that we don’t visually see, then you have also the blood vessels, the lungs, a lot of the connective tissue. The extracellular matrix proteins and elastin itself are also aging in the same way and have their own form of damage one way or another. All of this contributes to aging and aging-related diseases as well."
"Another kind of disease is the category of rare diseases. In this case, we aim to target Williams syndrome, a rare disease characterized by a genetic partial deletion of around 26 genes. One of these genes is elastin itself, so some genetic material is still there, but there is not enough. We would like to try to push the elastin production up in Williams syndrome, and this would help rectify a lot of the disease issues, particularly when it comes to the cardiovascular system because Williams syndrome patients have quite a lot of issues with the cardiovascular system from birth and all through life."
#ElastinBiosciences #Aging #AgingRelatedDiseases #Elastin #WilliamsSyndrome
