Addressing Extracellular Matrix Breakdown That Leads to Age-Related Diseases with Dr. Sherif Idriss Elastin Biosciences TRANSCRIPT
Release Date: 09/24/2024
AI-Powered Diagnostic Platform Connects Medical Specialists and Patients to Solve Complex Healthcare Cases with Haresh Patel Diagnostic MD AI TRANSCRIPT
Empowered Patient Podcast
Haresh Patel, Founder of Diagnostic MD AI, discusses the transformative potential of AI in healthcare diagnostics, particularly for patients with chronic or complex issues. Based on his own struggle to get an accurate diagnosis of an autoimmune condition, Haresh has developed a patient-centric platform where individuals can build their complete health story, integrating modern and functional medicine with a more holistic approach, which AI analyzes to help doctors connect disparate symptoms, ask the right questions, identify patterns, and reach the correct diagnosis faster while reducing...
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AI-Powered Diagnostic Platform Connects Medical Specialists and Patients to Solve Complex Healthcare Cases with Haresh Patel Diagnostic MD AI
Empowered Patient Podcast
Haresh Patel, Founder of Diagnostic MD AI, discusses the transformative potential of AI in healthcare diagnostics, particularly for patients with chronic or complex issues. Based on his own struggle to get an accurate diagnosis of an autoimmune condition, Haresh has developed a patient-centric platform where individuals can build their complete health story, integrating modern and functional medicine with a more holistic approach, which AI analyzes to help doctors connect disparate symptoms, ask the right questions, identify patterns, and reach the correct diagnosis faster while reducing...
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How EHR Systems Use Clinical AI to Advance Interoperability with Ben Scharfe Altera Digital Health TRANSCRIPT
Empowered Patient Podcast
Ben Scharfe, Executive VP of AI at Altera Digital Health, addresses the evolving regulatory landscape for AI in healthcare, emphasizing AI developers' primary responsibility to ensure transparency so clinicians can understand and verify AI-generated outputs. AI is positioned to be a supportive tool for providers, not as an autonomous decision-maker, with emerging regulations beginning to codify the human-in-the-loop requirement. Ben warns of setting higher standards for AI than physicians and automation complacency, in which clinicians might over-rely on AI. Ben explains, "Altera provides...
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How EHR Systems Use Clinical AI to Advance Interoperability with Ben Scharfe Altera Digital Health
Empowered Patient Podcast
Ben Scharfe, Executive VP of AI at Altera Digital Health, addresses the evolving regulatory landscape for AI in healthcare, emphasizing AI developers' primary responsibility to ensure transparency so clinicians can understand and verify AI-generated outputs. AI is positioned to be a supportive tool for providers, not as an autonomous decision-maker, with emerging regulations beginning to codify the human-in-the-loop requirement. Ben warns of setting higher standards for AI than physicians and automation complacency, in which clinicians might over-rely on AI. Ben explains, "Altera provides...
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Hospital Medicine Group Utilizing AI to Enhance Value-Based Care with Dr. John Birkmeyer Sound Physicians TRANSCRIPT
Empowered Patient Podcast
Dr. John Birkmeyer, President of the medical group at Sound Physicians, defines value-based care as an evolution from older managed care models, with closer alignment of incentives for quality of care and cost-effectiveness. Working within the hospital environment, this approach emphasizes standardizing patient-centered care and communication across multiple hospital departments, reducing redundant tests and improving patient outcomes. The use of AI is one way to reduce the administrative burden on physicians, freeing up more time for patient care, a departure from earlier technologies that...
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Hospital Medicine Group Utilizing AI to Enhance Value-Based Care with Dr. John Birkmeyer Sound Physicians
Empowered Patient Podcast
Dr. John Birkmeyer, President of the medical group at Sound Physicians, defines value-based care as an evolution from older managed care models, with closer alignment of incentives for quality of care and cost-effectiveness. Working within the hospital environment, this approach emphasizes standardizing patient-centered care and communication across multiple hospital departments, reducing redundant tests and improving patient outcomes. The use of AI is one way to reduce the administrative burden on physicians, freeing up more time for patient care, a departure from earlier technologies that...
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Extensive Myeloma Biobank Advancing Research in Blood Cancer Detection and Therapies with Dr. Jim Berenson Institute for Myeloma & Bone Cancer Research TRANSCRIPT
Empowered Patient Podcast
Dr. Jim Berenson, Founder of the Institute for Myeloma & Bone Cancer Research and the Berenson Cancer Center, describes the Institute's work, which includes maintaining a large biobank of patient samples that support both its own research and that being conducted by external groups. This biobank is being used to develop new blood markers for faster disease diagnosis, to assess treatment efficacy, and to support drug development for multiple myeloma and other cancers. Real-time monitoring of patient symptoms with a mobile app is capturing critical, often-missed patient data and providing...
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Extensive Myeloma Biobank Advancing Research in Blood Cancer Detection and Therapies with Dr. Jim Berenson Institute for Myeloma & Bone Cancer Research
Empowered Patient Podcast
Dr. Jim Berenson, Founder of the Institute for Myeloma & Bone Cancer Research and the Berenson Cancer Center, describes the Institute's work, which includes maintaining a large biobank of patient samples that support both its own research and that being conducted by external groups. This biobank is being used to develop new blood markers for faster disease diagnosis, to assess treatment efficacy, and to support drug development for multiple myeloma and other cancers. Real-time monitoring of patient symptoms with a mobile app is capturing critical, often-missed patient data and providing...
info_outline
Next-Generation Imaging Catheter for Enhanced Coronary Interventions with Tom Looby Conavi TRANSCRIPT
Empowered Patient Podcast
Tom Looby, CEO of Conavi, is focused on developing hybrid intravascular imaging technology that combines two established modalities into a single imaging catheter to provide a comprehensive view of the coronary arteries. This eliminates blind spots when using either intravascular ultrasound (IVUS) or optical coherence tomography (OCT) alone and is driving a shift away from relying solely on traditional angiography toward the use of advanced intravascular imaging to guide coronary procedures. Using AI to analyze dual-stream co-registered data allows interventional cardiologists to more...
info_outline
Next-Generation Imaging Catheter for Enhanced Coronary Interventions with Tom Looby Conavi
Empowered Patient Podcast
Tom Looby, CEO of Conavi, is focused on developing hybrid intravascular imaging technology that combines two established modalities into a single imaging catheter to provide a comprehensive view of the coronary arteries. This eliminates blind spots when using either intravascular ultrasound (IVUS) or optical coherence tomography (OCT) alone and is driving a shift away from relying solely on traditional angiography toward the use of advanced intravascular imaging to guide coronary procedures. Using AI to analyze dual-stream co-registered data allows interventional cardiologists to more...
info_outlineDr. Sherif Idriss is the CEO of Elastin Biosciences, a company focused on targeting aging-related diseases by restoring elastin, a key protein in the extracellular matrix that provides elasticity and resilience to organs and tissues. They are developing small molecule therapies for diseases linked to elastin deficiency, including Williams syndrome and abdominal aortic aneurysm. As elastin degrades over time due to aging, it leads to loss of tissue structural integrity and function, contributing to numerous age-related diseases.
Sherif explains, "One of the hallmarks of aging is the loss of the extracellular matrix, which is composed of several proteins. Collagen is quite famous, but also elastin is the other major protein that is responsible for the elasticity of the different organs. For example, in our skin, the loss of elastin is associated with us looking older and having all the aging signs and wrinkles on the skin. If you imagine that there are other organs inside that we don’t visually see, then you have also the blood vessels, the lungs, a lot of the connective tissue. The extracellular matrix proteins and elastin itself are also aging in the same way and have their own form of damage one way or another. All of this contributes to aging and aging-related diseases as well."
"Another kind of disease is the category of rare diseases. In this case, we aim to target Williams syndrome, a rare disease characterized by a genetic partial deletion of around 26 genes. One of these genes is elastin itself, so some genetic material is still there, but there is not enough. We would like to try to push the elastin production up in Williams syndrome, and this would help rectify a lot of the disease issues, particularly when it comes to the cardiovascular system because Williams syndrome patients have quite a lot of issues with the cardiovascular system from birth and all through life."
#ElastinBiosciences #Aging #AgingRelatedDiseases #Elastin #WilliamsSyndrome
