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Localized Immunotherapy to Treat Metastatic Prostate Cancer with Dr. Chuck Link Syncromune TRANSCRIPT

Empowered Patient Podcast

Release Date: 06/19/2025

Using AI to Address Medical Record Dirty Data  with Dr. Jay Anders Medicomp TRANSCRIPT show art Using AI to Address Medical Record Dirty Data with Dr. Jay Anders Medicomp TRANSCRIPT

Empowered Patient Podcast

Dr. Jay Anders, Chief Medical Officer at Medicomp Systems, discusses the issue of dirty data — inaccurate and inconsistent medical data — and its origins, as well as how technology can be used to maintain correct health records. These kinds of errors can lead to incorrect diagnoses, inappropriate treatment, and negative consequences for patients, providers, and payers. AI and other technologies are being leveraged to help identify and flag inconsistencies, providing stakeholders with the tools to prioritize accuracy over efficiency.  Jay explains, "What we do at Medicomp is a...

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Using AI to Address Medical Record Dirty Data with Dr. Jay Anders Medicomp show art Using AI to Address Medical Record Dirty Data with Dr. Jay Anders Medicomp

Empowered Patient Podcast

Dr. Jay Anders, Chief Medical Officer at Medicomp Systems, discusses the issue of dirty data — inaccurate and inconsistent medical data — and its origins, as well as how technology can be used to maintain correct health records. These kinds of errors can lead to incorrect diagnoses, inappropriate treatment, and negative consequences for patients, providers, and payers. AI and other technologies are being leveraged to help identify and flag inconsistencies, providing stakeholders with the tools to prioritize accuracy over efficiency.  Jay explains, "What we do at Medicomp is a...

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Ultra-Fast Cardiac CT Imaging Transforming Cardiovascular Diagnostics with Doug Ryan Arineta TRANSCRIPT show art Ultra-Fast Cardiac CT Imaging Transforming Cardiovascular Diagnostics with Doug Ryan Arineta TRANSCRIPT

Empowered Patient Podcast

Doug Ryan, CEO of Arineta, describes the advancements in cardiac CT imaging technology and how their ultra-fast scanning is revealing more accurate and higher-quality imaging of the heart. Using wide-area coverage and deep learning image reconstruction, the Arineta platform can detect arterial occlusions and coronary plaque buildup, which is a significant risk factor for sudden cardiac events and is often missed when relying solely on calcium scoring. The development of a mobile cardiac CT scanning unit is improving access to this technology, particularly in rural and underserved areas. Doug...

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Ultra-Fast Cardiac CT Imaging Transforming Cardiovascular Diagnostics with Doug Ryan Arineta show art Ultra-Fast Cardiac CT Imaging Transforming Cardiovascular Diagnostics with Doug Ryan Arineta

Empowered Patient Podcast

Doug Ryan, CEO of Arineta, describes the advancements in cardiac CT imaging technology and how their ultra-fast scanning is revealing more accurate and higher-quality imaging of the heart. Using wide-area coverage and deep learning image reconstruction, the Arineta platform can detect arterial occlusions and coronary plaque buildup, which is a significant risk factor for sudden cardiac events and is often missed when relying solely on calcium scoring. The development of a mobile cardiac CT scanning unit is improving access to this technology, particularly in rural and underserved areas. Doug...

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Cybersecurity and Hidden Dangers of Healthcare Interoperability with Kory Daniels Trustwave TRANSCRIPT show art Cybersecurity and Hidden Dangers of Healthcare Interoperability with Kory Daniels Trustwave TRANSCRIPT

Empowered Patient Podcast

Kory Daniels, Chief Information Security Officer at Trustwave,  highlights the unique cybersecurity challenges facing the healthcare industry, particularly in this environment of funding constraints and the increasing sophistication of cyberattacks. Healthcare data is highly valuable to cybercriminals, who can use it for ransomware attacks, identity and insurance fraud, and other nefarious purposes. AI can be part of both the attack and the solution, helping to build in more cyber resilience and awareness about vulnerabilities. Kory explains, "Healthcare is a prime target for...

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Cybersecurity and Hidden Dangers of Healthcare Interoperability with Kory Daniels Trustwave show art Cybersecurity and Hidden Dangers of Healthcare Interoperability with Kory Daniels Trustwave

Empowered Patient Podcast

Kory Daniels, Chief Information Security Officer at Trustwave,  highlights the unique cybersecurity challenges facing the healthcare industry, particularly in this environment of funding constraints and the increasing sophistication of cyberattacks. Healthcare data is highly valuable to cybercriminals, who can use it for ransomware attacks, identity and insurance fraud, and other nefarious purposes. AI can be part of both the attack and the solution, helping to build in more cyber resilience and awareness about vulnerabilities. Kory explains, "Healthcare is a prime target for...

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How AI and Telehealth are Transforming Patient Access with Matt Brown CHG Healthcare TRANSCRIPT show art How AI and Telehealth are Transforming Patient Access with Matt Brown CHG Healthcare TRANSCRIPT

Empowered Patient Podcast

Matt Brown, VP of Telehealth at Advisory Services at CHG Healthcare, discusses the current state and future of telehealth, including the rapid adoption during the COVID-19 pandemic, the role of technology and AI in enhancing telehealth experiences, and how telehealth can help address physician and nurse burnout. Improved internet access, mobile device usage, and consumer preferences for convenience have driven the increasing telehealth usage for initial visits, follow-up appointments, and chronic care management.   Matt explains, "We are the nation's largest staffing agency. So, we're...

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How AI and Telehealth are Transforming Patient Access with Matt Brown CHG Healthcare show art How AI and Telehealth are Transforming Patient Access with Matt Brown CHG Healthcare

Empowered Patient Podcast

Matt Brown, VP of Telehealth at Advisory Services at CHG Healthcare, discusses the current state and future of telehealth, including the rapid adoption during the COVID-19 pandemic, the role of technology and AI in enhancing telehealth experiences, and how telehealth can help address physician and nurse burnout. Improved internet access, mobile device usage, and consumer preferences for convenience have driven the increasing telehealth usage for initial visits, follow-up appointments, and chronic care management.   Matt explains, "We are the nation's largest staffing agency. So, we're...

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Localized Immunotherapy to Treat Metastatic Prostate Cancer with Dr. Chuck Link Syncromune TRANSCRIPT show art Localized Immunotherapy to Treat Metastatic Prostate Cancer with Dr. Chuck Link Syncromune TRANSCRIPT

Empowered Patient Podcast

Dr. Chuck Link is the Executive Chairman of Syncromune, a company developing a novel immunotherapy approach for solid tumors by delivering the therapy into the tumor and surrounding lymph nodes to stimulate a systemic immune response. Their complex drug has four different components with varying levels of activity that activate the immune system and counteract immune suppression. This in situ immunotherapy technology, SYNC-T, was tested in a phase 1 trial for metastatic castration-resistant prostate cancer, which showed high response rates and a favorable safety profile with low rates of...

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Localized Immunotherapy to Treat Metastatic Prostate Cancer with Dr. Chuck Link Syncromune show art Localized Immunotherapy to Treat Metastatic Prostate Cancer with Dr. Chuck Link Syncromune

Empowered Patient Podcast

Dr. Chuck Link is the Executive Chairman of Syncromune, a company developing a novel immunotherapy approach for solid tumors by delivering the therapy into the tumor and surrounding lymph nodes to stimulate a systemic immune response. Their complex drug has four different components with varying levels of activity that activate the immune system and counteract immune suppression. This in situ immunotherapy technology, SYNC-T, was tested in a phase 1 trial for metastatic castration-resistant prostate cancer, which showed high response rates and a favorable safety profile with low rates of...

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Dr. Chuck Link is the Executive Chairman of Syncromune, a company developing a novel immunotherapy approach for solid tumors by delivering the therapy into the tumor and surrounding lymph nodes to stimulate a systemic immune response. Their complex drug has four different components with varying levels of activity that activate the immune system and counteract immune suppression. This in situ immunotherapy technology, SYNC-T, was tested in a phase 1 trial for metastatic castration-resistant prostate cancer, which showed high response rates and a favorable safety profile with low rates of serious side effects and minimal autoimmune toxicity.  

Chuck explains, "So, SYNC-T is a technology in which you put a needle directly into a tumor that can be done by a urologist in the prostate cancer situation, or by an interventional radiologist. That needle then the tip of it freezes, and does a freeze fracture. Think of a Coke bottle rupturing like in the freezer. And what that does is release the antigens from that patient's own specific tumor. So, it's personalized because the tumor proteins and antigens are used to create a vaccine effect that's released directly from the cancer."

"The tumor microenvironment is basically within the tumor itself, and there are immune suppressive mechanisms that the tumor has evolved to protect it from the immune system. I like to think of it as a castle, multiple levels of defense where you have the castle itself, and then you have a castle wall, and then you have a moat, and then an army in front of the wall. So the cancer has multiple immune-suppressive mechanisms that are activated to defeat the immune system, even though cancer has a lot of abnormal, mutated proteins that the immune system should attack and destroy. So what SYNC-T accomplishes is it basically hits solutions for all four of those types of defense simultaneously to make it more difficult for the castle, in this case, the tumor, to protect itself."

#Syncromune #Immunotherapy #MetastaticSolidTumors #Cancer #ProstateCancer

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