Multimodal AI Platform Enables Precision-Guided Prostate Cancer Treatment with Shyam Natarajan Avenda Health
Release Date: 05/22/2025
Empowered Patient Podcast
Barry Quart, CEO of Connect Biopharma, is developing the next generation of monoclonal antibodies targeting inflammatory respiratory diseases such as COPD and asthma. Administered subcutaneously, their lead program targets IL-4 and has demonstrated the ability to rapidly improve airway function and reduce the incidence of acute exacerbations in these patients. Current treatments rely on steroids and bronchodilators, which do not address the underlying inflammatory causes, an area that has largely been under-addressed by other biologic developers. Barry explains, "Connect has been dedicated...
info_outlineEmpowered Patient Podcast
Barry Quart, CEO of Connect Biopharma, is developing the next generation of monoclonal antibodies targeting inflammatory respiratory diseases such as COPD and asthma. Administered subcutaneously, their lead program targets IL-4 and has demonstrated the ability to rapidly improve airway function and reduce the incidence of acute exacerbations in these patients. Current treatments rely on steroids and bronchodilators, which do not address the underlying inflammatory causes, an area that has largely been under-addressed by other biologic developers. Barry explains, "Connect has been dedicated...
info_outlineEmpowered Patient Podcast
Dr. Kilian Kelly, Chief Executive Officer and Managing Director of Cynata Therapeutics, has taken on the challenge of manufacturing stem cell therapies consistently and at scale in order to drive the advancements necessary for the next generation of regenerative medicine. Cynata is employing a novel approach that utilizes a single source of pluripotent stem cells (iPSCs) and mesenchymal cell ancestors (MCAs) to generate mesenchymal stem cells (MSCs). Lead programs are targeting graft-versus-host disease, osteoarthritis, and diabetic wounds, where clinical trials have shown great promise to...
info_outlineEmpowered Patient Podcast
Dr. Kilian Kelly, Chief Executive Officer and Managing Director of Cynata Therapeutics, has taken on the challenge of manufacturing stem cell therapies consistently and at scale in order to drive the advancements necessary for the next generation of regenerative medicine. Cynata is employing a novel approach that utilizes a single source of pluripotent stem cells (iPSCs) and mesenchymal cell ancestors (MCAs) to generate mesenchymal stem cells (MSCs). Lead programs are targeting graft-versus-host disease, osteoarthritis, and diabetic wounds, where clinical trials have shown great promise to...
info_outlineEmpowered Patient Podcast
Shauna Sweeney, Founder of tendercare, aims to assist caregivers with digital tools and expert support to simplify the process of caring for an aging family member. Recognizing the essential role of caregivers in the quality of life of the patient, tendercare provides a user-friendly interface that incorporates data from wearables and remote sensors to identify early warning signs of risks, help coordinate care, and encourage proactive preparation. The Magic Magnet feature allows caregivers and emergency responders to quickly update and share critical health information. Shauna...
info_outlineEmpowered Patient Podcast
Shauna Sweeney, Founder of tendercare, aims to assist caregivers with digital tools and expert support to simplify the process of caring for an aging family member. Recognizing the essential role of caregivers in the quality of life of the patient, tendercare provides a user-friendly interface that incorporates data from wearables and remote sensors to identify early warning signs of risks, help coordinate care, and encourage proactive preparation. The Magic Magnet feature allows caregivers and emergency responders to quickly update and share critical health information. Shauna...
info_outlineEmpowered Patient Podcast
Karen Sussman Horgan is the Co-Founder and CEO of VAL Health, a behavioral economics consulting firm that helps healthcare organizations drive engagement and nudge patients to improve their health and lifestyle choices. Behavioral economics is the science of understanding how patients make irrational choices based on biases, fear, and faulty analysis of outcomes and risk. Nudges can be carrots or sticks, but in healthcare, the focus is on making the right path easier to follow, reducing friction, and introducing positive reinforcements rather than penalties. Karen explains, "We work across...
info_outlineEmpowered Patient Podcast
Karen Sussman Horgan is the Co-Founder and CEO of VAL Health, a behavioral economics consulting firm that helps healthcare organizations drive engagement and nudge patients to improve their health and lifestyle choices. Behavioral economics is the science of understanding how patients make irrational choices based on biases, fear, and faulty analysis of outcomes and risk. Nudges can be carrots or sticks, but in healthcare, the focus is on making the right path easier to follow, reducing friction, and introducing positive reinforcements rather than penalties. Karen explains, "We work across...
info_outlineEmpowered Patient Podcast
Christine Lee, Head of Health Strategy and Partnerships at AnalyticsIQ, focuses on helping healthcare brands and pharmaceutical companies better understand and engage with healthcare providers by taking into account data beyond their professional lives. This data-driven Provider as a Person approach analyzes the healthcare professional's personal characteristics, outside interests, decision-making style, and preferred method of communication. The goal is to foster more meaningful relationships with providers, address provider burnout, and improve patient outcomes. Christine explains,...
info_outlineEmpowered Patient Podcast
Christine Lee, Head of Health Strategy and Partnerships at AnalyticsIQ, focuses on helping healthcare brands and pharmaceutical companies better understand and engage with healthcare providers by taking into account data beyond their professional lives. This data-driven Provider as a Person approach analyzes the healthcare professional's personal characteristics, outside interests, decision-making style, and preferred method of communication. The goal is to foster more meaningful relationships with providers, address provider burnout, and improve patient outcomes. Christine explains,...
info_outlineShyam Natarajan, Founder and CEO of Avenda Health, is utilizing the Unfold AI platform that combines imaging, pathology, and clinical data to provide a comprehensive 3D visualization of prostate cancer. This platform has demonstrated significantly higher accuracy than conventional imaging techniques, enabling physicians to make more informed diagnoses and treatment decisions. The technology has been integrated into the clinical workflow to provide real-time insights and precision-guided interventions, minimizing treatment-related side effects and preserving patient quality of life.
Shyam explains, "Unfold AI is unique in that it's multimodal. We take in imaging biomarkers, pathology, and clinical information as input. And conventional imaging really doesn't show you exactly everywhere the cancer is. MRI today misses two-thirds of the disease by volume, and so imaging is really good at screening and that initial diagnosis. But when it comes time to decide how to treat patients, the standard of care is challenging today because, really, up to a third of patients end up having cancer left behind after treatment. So what we're trying to solve is this pain point where cancer is missed, and as a consequence, cancer is left behind."
"This product is really for patients who have a diagnosis of what we call clinically significant or cancer that you have to do something about. So, it’s not the very low-risk, where being on what's called surveillance, watch and wait, is probably more appropriate. But this product, you touched upon the value proposition where a lot of patients are coming to their doctor saying, Hey Doc, I don't want to get surgery because I'm scared of the quality of life outcomes or the side effect profile. They want to get a targeted therapy. Well, physicians really can't offer targeted therapy in a broad sense unless they know where the cancer is. And so, AI is empowering and enabling physicians to perform precision-guided therapy or focal therapy."
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