Patient-Centric Drug Development for Ovarian Cancer Targets Tumor Survival Pathway with Dr. Stella Vnook Kaida Biopharma TRANSCRIPT
Release Date: 05/19/2026
Using Technology to Address Preventable Medical Harm with Joe Kiani Patient Safety Movement Foundation TRANSCRIPT
Empowered Patient Podcast
Joe Kiani is Executive Chairman at Willow Laboratories and Founder of the Patient Safety Movement Foundation. He makes the point that the vast majority of medical harm is avoidable through the implementation of evidence-based healthcare best practices. Technology, particularly AI and remote monitoring of data from medical devices, is crucial for creating predictive models that can alert clinicians to problems and identify root causes of medical errors. The goal is to unite all healthcare stakeholders to work collaboratively toward zero preventable deaths. Joe explains, "In the US,...
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Using Technology to Address Preventable Medical Harm with Joe Kiani Patient Safety Movement Foundation
Empowered Patient Podcast
Joe Kiani is Executive Chairman at Willow Laboratories and Founder of the Patient Safety Movement Foundation. He makes the point that the vast majority of medical harm is avoidable through the implementation of evidence-based healthcare best practices. Technology, particularly AI and remote monitoring of data from medical devices, is crucial for creating predictive models that can alert clinicians to problems and identify root causes of medical errors. The goal is to unite all healthcare stakeholders to work collaboratively toward zero preventable deaths. Joe explains, "In the US,...
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Digitizing Hospital Workflows Boosts Efficiency and Patient Outcomes with Sam Yeruva PyCube TRANSCRIPT
Empowered Patient Podcast
Sam Yeruva is Founder and CEO of PyCube, a company that provides software solutions to US hospitals to digitize workflows and improve operational efficiency. He points out that many hospital processes still rely on paper, which hinders the collection of data necessary for operational intelligence and forecasting. The key to success is breaking down data silos across departments to better track assets, samples, and pharmaceuticals, improving patient care, reducing clinician burnout, and driving cost savings. Sam explains, "PyCube is a software solutions company serving US health...
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Digitizing Hospital Workflows Boosts Efficiency and Patient Outcomes with Sam Yeruva PyCube
Empowered Patient Podcast
Sam Yeruva is Founder and CEO of PyCube, a company that provides software solutions to US hospitals to digitize workflows and improve operational efficiency. He points out that many hospital processes still rely on paper, which hinders the collection of data necessary for operational intelligence and forecasting. The key to success is breaking down data silos across departments to better track assets, samples, and pharmaceuticals, improving patient care, reducing clinician burnout, and driving cost savings. Sam explains, "PyCube is a software solutions company serving US health...
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Micro-Wearable Delivers Continuous Hydration Monitoring and Biomarker Insights with Professor Mark Kendall WearOptimo TRANSCRIPT
Empowered Patient Podcast
Professor Mark Kendall, Founder and CEO of WearOptimo, is a pioneer in micro-wearable technology and highlights the limitations of current wearables that capture only basic signals. The WearOptimo platform uses a skin patch with painless microelectrodes to measure a range of biomarkers in the interstitial fluid just beneath the skin surface. The company's first product is a continuous hydration monitor designed to address the widespread and under-recognized health problems caused by dehydration due to lifestyle, disease, and working conditions. Mark explains, "We are all familiar...
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Micro-Wearable Delivers Continuous Hydration Monitoring and Biomarker Insights with Professor Mark Kendall WearOptimo
Empowered Patient Podcast
Professor Mark Kendall, Founder and CEO of WearOptimo, is a pioneer in micro-wearable technology and highlights the limitations of current wearables that capture only basic signals. The WearOptimo platform uses a skin patch with painless microelectrodes to measure a range of biomarkers in the interstitial fluid just beneath the skin surface. The company's first product is a continuous hydration monitor designed to address the widespread and under-recognized health problems caused by dehydration due to lifestyle, disease, and working conditions. Mark explains, "We are all familiar...
info_outline
Patient-Centric Drug Development for Ovarian Cancer Targets Tumor Survival Pathway with Dr. Stella Vnook Kaida Biopharma TRANSCRIPT
Empowered Patient Podcast
Dr. Stella Vnook, Co-Founder and Executive Chair of Kaida Biopharma, highlights the advantages for an early-stage biotech company to take a patient-centric perspective in drug development. She defines patient-centricity as focusing on whether a drug meaningfully improves a patient's life, which should influence decisions about trial design, endpoints, and side effects from the earliest stages. Kaida's work on a new treatment for ovarian cancer is designed to target tumor survival mechanisms and overcome treatment resistance, and has from the beginning taken into consideration the tolerability...
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Patient-Centric Drug Development for Ovarian Cancer Targets Tumor Survival Pathway with Dr. Stella Vnook Kaida Biopharma
Empowered Patient Podcast
Dr. Stella Vnook, Co-Founder and Executive Chair of Kaida Biopharma, highlights the advantages for an early-stage biotech company to take a patient-centric perspective in drug development. She defines patient-centricity as focusing on whether a drug meaningfully improves a patient's life, which should influence decisions about trial design, endpoints, and side effects from the earliest stages. Kaida's work on a new treatment for ovarian cancer is designed to target tumor survival mechanisms and overcome treatment resistance, and has from the beginning taken into consideration the tolerability...
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Redefining Primary Care for Older Women with Dr. Deb Dittberner Herself Health TRANSCRIPT
Empowered Patient Podcast
Dr. Deb Dittberner, Chief Clinical Officer and Director of Population Health at Herself Health, focuses on providing value-based care for women aged 50 and older through a model that prioritizes cognition, bone health, behavioral health, and cardiac health. Conventional primary care for older women often overlooks the complexities of aging, which Herself Health addresses through longer visits, proactive screening, and patient education. Technology is being successfully integrated into the environment to provide virtual visits, support medication adherence, and improve access to care. ...
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Redefining Primary Care for Older Women with Dr. Deb Dittberner Herself Health
Empowered Patient Podcast
Dr. Deb Dittberner, Chief Clinical Officer and Director of Population Health at Herself Health, focuses on providing value-based care for women aged 50 and older through a model that prioritizes cognition, bone health, behavioral health, and cardiac health. Conventional primary care for older women often overlooks the complexities of aging, which Herself Health addresses through longer visits, proactive screening, and patient education. Technology is being successfully integrated into the environment to provide virtual visits, support medication adherence, and improve access to care. ...
info_outlineDr. Stella Vnook, Co-Founder and Executive Chair of Kaida Biopharma, highlights the advantages for an early-stage biotech company to take a patient-centric perspective in drug development. She defines patient-centricity as focusing on whether a drug meaningfully improves a patient's life, which should influence decisions about trial design, endpoints, and side effects from the earliest stages. Kaida's work on a new treatment for ovarian cancer is designed to target tumor survival mechanisms and overcome treatment resistance, and has from the beginning taken into consideration the tolerability of treatments and the patient's quality of life.
Stella explains, "We're so used to thinking drug-centric, and it's true that in the early stages of development, it's all about the molecule and the mechanism of action, and it's exciting to see how it works. But we really need to be thinking patient-centric because we will make decisions differently from the start. So it's not just about whether this drug works and how, but whether it meaningfully changes a patient's life. I think that's what patient-centric is or should be, because that would impact trial design, endpoints, and how we view tolerability or combination therapy."
"For ovarian cancer, women today may receive a variety of treatments. Now, let's talk about this for a second. It's the cancer that's usually diagnosed very late. That means the patient's tumor has already gone into the lymph nodes, and it's what we call a stage three PO4. The patients after surgery receive a variety of drugs such as platinum therapies or PARP, but they still may relapse, and they may become resistant to the therapy. Now, that initial therapy has probably had significant toxicity. Because they've become resistant to the therapy they received, now they have limited options. So fortunately, there are drugs that potentially could be eligible for FRA positive. There's been a lot of news about ELAHERE, which is great, but it's only 25% of the population, and many patients may never qualify for this treatment. So that's where Kaida comes in, because we're focusing on 80% of the population."
"Actually, the name Kaida is a dragon that eats its own tail. So that talks about the mechanism of action we've discussed: resistance. What we do is when the treatment has been given, it supports cell survival and actually eliminates the tumor's ability to replicate, which is called proliferation, causing it to destroy itself, which is called apoptosis. So in essence, the tumor disrupts itself because we're cutting off its support system."
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