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Fat Loss Without Muscle Loss: Researcher & Scientist with Dr. Eric Trexler

Optimal Protein Podcast with Vanessa Spina

Release Date: 03/10/2025

Dr. Gabrielle Lyon's Clinical Nutritionist Julia Mitchell: From Fat Loss to Body Recomposition- Why Muscle is the Missing Link show art Dr. Gabrielle Lyon's Clinical Nutritionist Julia Mitchell: From Fat Loss to Body Recomposition- Why Muscle is the Missing Link

Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy. Go to timeline.com/vanessa. In this episode, I sit down with Julia Mitchell to explore the principles of muscle-centric medicine and the critical role muscle plays in overall health, longevity, and body composition. We discuss practical strategies for achieving your fitness goals, from optimizing protein intake to structuring your day for success, and choosing the right carbs and fats for muscle growth. In this episode, you’ll learn: The core fundamentals of achieving the body composition you want How to set yourself...

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The Biggest Fitness Myths for Women: What The Scientific Data Shows (Must Listen Episode) show art The Biggest Fitness Myths for Women: What The Scientific Data Shows (Must Listen Episode)

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this myth-busting solo episode, Vanessa recaps her powerful conversation with Dr. Lauren Colenso-Semple — a leading researcher in women’s physiology and strength training — and breaks down the real science behind the most persistent myths in women’s fitness and hormones. From fasted training to protein timing, lifting heavy, cortisol,...

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Exposing the Truth: Fasted Workouts, Lifting Heavy, Protein Timing, HRT, Cortisol, & More: Dr. Lauren Colenso-Semple show art Exposing the Truth: Fasted Workouts, Lifting Heavy, Protein Timing, HRT, Cortisol, & More: Dr. Lauren Colenso-Semple

Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy.  Go to . In this myth-busting episode of The Optimal Protein Podcast, host Vanessa Spina is joined once again by Dr. Lauren Colenso-Semple — one of the most trusted voices in evidence-based women’s health and strength training. Social media is overflowing with advice on what women should and shouldn’t do when it comes to building muscle, managing hormones, and training across the menstrual cycle. But how much of it is actually backed by science? Dr. Lauren joins us to expose the truth behind the most persistent...

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Exactly What to Eat on High-Protein Keto show art Exactly What to Eat on High-Protein Keto

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Wondering what to eat in a day on high-protein keto — and how much? In this solo episode, Vanessa lays out your exact roadmap to eating for fat loss, satiety, and energy on a high-protein ketogenic diet. You’ll learn: How to set your macros (without overthinking it) How to calculate your protein target for results What a full day of eating...

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Building Muscle, Burning Fat & Eating Enough Protein – with Dr. Mike Israetel show art Building Muscle, Burning Fat & Eating Enough Protein – with Dr. Mike Israetel

Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy.  Go to . Ready to cut through the noise and actually build muscle and lose fat? Dr. Mike Israetel joins me to break down the simple science behind protein intake, hypertrophy training, and smart recovery — all in a way that’s perfect for beginners. If you want real results, not just internet fitness myths — this episode is for you. Visit  for 30% OFF your subscription order PLUS receive a free gift with your second shipment—fun surprises like a free 6-pack, Ketone-IQ merch, and more!...

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Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this solo deep-dive, Vanessa breaks down her full-length interview with Dr. Ted Naiman, author of Satiety Per Calorie: Eating, Solved. This is the episode for anyone tired of dieting, confused by nutrition extremes, or struggling to lose fat sustainably. Vanessa walks you through every major insight from the episode, from the four levers of...

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Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy.  Go to . In this powerful and practical episode, Vanessa sits down with returning guest Dr. Ted Naiman—board-certified physician, fitness expert, and author of the new book Satiety Per Calorie: Eating, Solved. Together, they unpack the revolutionary concept that could change the way you eat forever: satiety per calorie—a simple but groundbreaking way to eat more food, feel fuller, and effortlessly lose fat. Dr. Naiman explains why our modern food environment has hijacked hunger, how food processing dilutes satiety,...

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Ready for a Reset? Your Easy Start Guide to Higher Protein Keto! show art Ready for a Reset? Your Easy Start Guide to Higher Protein Keto!

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Feel like your metabolism needs a reboot? In this special solocast, Vanessa Spina shares a full audio walkthrough of the Keto Reset — a simplified, protein-prioritized approach to fat adaptation and sustainable fat loss. Whether you’re new to keto or ready to do it right, this episode is your personal guide to resetting your body for real...

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Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy.  Go to . What if the key to a leaner body, a clearer mind, and total food freedom isn’t willpower… but your gut bacteria? In this powerful episode of The Optimal Protein Podcast, I’m joined by world-renowned physician, author, and gut health pioneer Dr. Steven Gundry to dive into the bold insights from his new book, The Gut-Brain Paradox. Dr. Gundry reveals how an imbalanced microbiome doesn’t just affect digestion — it can hijack your cravings, dull your focus, and even impact your mood, behavior, and...

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The New Keto: More Protein, Less Fat, Better Results show art The New Keto: More Protein, Less Fat, Better Results

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. What if the keto diet you thought you knew… was actually working against your goals? In this solo episode of The Optimal Protein Podcast, I’m breaking down what I call “The New Keto”—a science-backed, high-protein version of keto designed for fat loss, lean muscle retention, and metabolic flexibility. Based on the latest research and...

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More Episodes

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy.  Go to timeline.com/vanessa.

In this episode of The Optimal Protein Podcast, I’m joined by Dr. Eric Trexler, a renowned researcher and expert in exercise science, nutrition, and body composition. We dive deep into the strategies you can use to optimize protein intake, preserve lean muscle mass, and enhance fat loss.

Dr. Trexler shares actionable insights on how to structure your nutrition and training for better results — whether your goal is body recomposition, improved performance, or overall metabolic health.

Key Topics Discussed:

Protein Intake: How much protein you really need during fat loss to protect lean muscle.

Protein Distribution & Timing: Why spacing your protein intake across meals can improve muscle retention and recovery.

HIIT Training: How high-intensity interval training fits into a fat loss plan — and what you need to know for optimal results.

Creatine & Caffeine: The science behind these powerful supplements and how whether or not combining them lowers the effects of creatine.

✅ The key differences between fasted vs. fed cardio for fat loss.

✅ Practical tips for ensuring your training and nutrition strategies are aligned for long-term success.

Why You Should Tune In:

If you’re serious about preserving muscle while losing fat, this episode is packed with evidence-based insights you can apply right away. Dr. Trexler’s expertise bridges the gap between scientific research and practical application, making this a must-listen for anyone focused on body recomposition and metabolic health.

Get 20% off on the Tone LUX Crystal Red Light Therapy Mask Ketogenicgirl.com with the code VANESSA

Join the Community! Follow Vanessa on instagram to see her meals, recipes, informative posts and much more! Click here @ketogenicgirl

Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast.

Link to join the facebook group for the podcast: https://www.facebook.com/groups/2017506024952802/
 
The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.