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Change Your Shape, Not Just Your Weight — Dr. Mike Ormsbee on Protein Timing, Fat Loss & Muscle

Optimal Protein Podcast with Vanessa Spina

Release Date: 07/14/2025

Protein, Breaking News & Fat Loss: Dr. Don Layman’s Breaking Insights (Recap Part 1) show art Protein, Breaking News & Fat Loss: Dr. Don Layman’s Breaking Insights (Recap Part 1)

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. Jump to start of the episode: 13:30 In this Friday solo episode, Vanessa Spina breaks down the first half of her latest interview with Dr. Donald Layman — legendary protein researcher and one of the most featured guests in the history of the Optimal Protein Podcast. They cover game-changing updates to U.S. dietary guidelines, red meat’s misunderstood...

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Breaking News: Big Changes to the Dietary Guidelines Coming & What It Means for Fat Loss, Muscle & Metabolism: Dr. Don Layman (Part 1 of 2) show art Breaking News: Big Changes to the Dietary Guidelines Coming & What It Means for Fat Loss, Muscle & Metabolism: Dr. Don Layman (Part 1 of 2)

Optimal Protein Podcast with Vanessa Spina

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. This week on the Optimal Protein Podcast, I’m thrilled to be joined once again by Dr. Don Layman, one of the world’s foremost experts in protein metabolism and amino acid science. In this first part of our two-part conversation, we take a deep dive into the true definition of protein quality, the flaws of current scoring systems, and the...

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Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this solocast episode, Vanessa shares a detailed recap of her interview with Dr. Eduardo de Souza, associate professor at the University of Tampa and one of the world’s leading researchers in body recomposition and exercise science. This episode is a masterclass on building muscle and losing fat at the same time—even for trained individuals. ➡️...

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Optimal Protein Podcast with Vanessa Spina

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at . In this powerhouse episode, Dr. Eduardo de Souza breaks down the real science of body recomposition—how to lose fat and build muscle simultaneously, even for advanced lifters. He shares the key strategies proven to work: optimal training volume, smart calorie deficits, high protein intake, and the underrated role of sleep. If you’ve hit a plateau or want to...

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Change Your Shape, Not Just Your Weight: What Most Diets Miss: Dr. Mike Ormsbee Recap! show art Change Your Shape, Not Just Your Weight: What Most Diets Miss: Dr. Mike Ormsbee Recap!

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this solo recap episode, Vanessa breaks down the top takeaways from her interview with one of the world’s leading experts in body composition and metabolism — Dr. Mike Ormsbee, Professor at Florida State University and Director of the Institute of Sports Sciences and Medicine. Dr. Ormsbee has published over 200 peer-reviewed papers and is...

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Change Your Shape, Not Just Your Weight — Dr. Mike Ormsbee on Protein Timing, Fat Loss & Muscle show art Change Your Shape, Not Just Your Weight — Dr. Mike Ormsbee on Protein Timing, Fat Loss & Muscle

Optimal Protein Podcast with Vanessa Spina

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at . In this episode of the Optimal Protein Podcast, Vanessa Spina sits down with one of the world’s leading experts in sports nutrition and metabolism — Dr. Mike Ormsbee. With over 200 peer-reviewed publications, Dr. Ormsbee brings unmatched insight into how to optimize fat loss, preserve muscle, and transform your body composition through nutrition, protein...

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Burn Fat, Preserve Muscle, Dr. Arny Ferrando Recap!  show art Burn Fat, Preserve Muscle, Dr. Arny Ferrando Recap!

Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. This powerful solo episode recaps the most jaw-dropping insights from Vanessa’s recent conversation with Dr. Arny Ferrando—one of the world’s leading experts on human muscle metabolism, amino acids, and aging. Vanessa breaks down how muscle protein synthesis actually works on a physiological level, the surprising role of blood flow in getting...

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Optimal Protein Podcast with Vanessa Spina

Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at . In this powerhouse episode of the Optimal Protein Podcast, Vanessa Spina sits down with legendary muscle metabolism researcher Dr. Arny Ferrando for an in-depth masterclass on essential amino acids, protein timing, aging, anabolic resistance, and how to optimize muscle retention and fat loss—especially during menopause. Dr. Ferrando shares the latest research...

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Optimal Protein Podcast with Vanessa Spina

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000.  That’s VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. In this solo episode, Vanessa recaps her conversation with Dr. Eric Ravussin—one of the world’s foremost experts in metabolism, fat loss, and caloric restriction, author of the Biggest Loser and CALERIE studies. You’ll learn the truth about metabolic adaptation and why fat loss becomes harder over time, especially when using GLP-1 medications....

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Optimal Protein Podcast with Vanessa Spina

Timeline: Get 10% off Mitopure, clinically proven to boost mitophagy. Go to . Today’s episode features world-renowned metabolism expert Dr. Eric Ravussin, whose groundbreaking work has transformed our understanding of energy balance, calorie restriction, and long-term fat loss. Dr. Ravussin shares key insights from decades of clinical research on how the body adapts to weight loss—including why your metabolism slows, how to preserve lean muscle, and the critical role of mitochondrial health and metabolic flexibility. Visit for 30% OFF your subscription order PLUS receive a free gift...

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Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa.

In this episode of the Optimal Protein Podcast, Vanessa Spina sits down with one of the world’s leading experts in sports nutrition and metabolism — Dr. Mike Ormsbee. With over 200 peer-reviewed publications, Dr. Ormsbee brings unmatched insight into how to optimize fat loss, preserve muscle, and transform your body composition through nutrition, protein timing, and targeted exercise.

Vanessa and Dr. Ormsbee explore:

  • Why calorie restriction alone just makes you a smaller version of the same shape
  • How to change your body shape, not just your weight
  • The truth about pre-sleep protein intake — and why it doesn’t make you fat
  • How much protein you actually need daily (spoiler: it’s more than the RDA)
  • The science behind multi-modal training and the “PRISE” protocol
  • How women, especially during menopause, can benefit from a high-protein lifestyle
  • Real lab data from studies on metabolic rate, fat oxidation, and overnight muscle protein synthesis

Whether you’re trying to burn fat, gain muscle, or reshape your body — this is a must-listen episode packed with practical, evidence-based advice from one of the world’s most respected researchers in exercise science.

🧬 Topics Covered:

  • The science of body recomposition
  • Resistance training vs. cardio for reshaping your body
  • High-protein diets: optimal intake ranges
  • Meal timing and protein distribution strategies
  • Pre-sleep protein: benefits, myths, and studies
  • Research on resting metabolic rate and fat oxidation
  • Female-specific insights: menopause, recovery, and strength
  • The PRISE protocol and sustainable fat loss

📚 Mentioned in This Episode:

  • Changing Body Composition Through Diet and Exercise (course by Dr. Ormsbee – The Great Courses)
  • Dr. Ormsbee’s research via the FSU Institute of Sports Sciences and Medicine
  • The PRISE protocol (Protein, Resistance, Intervals, Stretching, Endurance)

📱 Connect with Dr. Mike Ormsbee:

  • Instagram: @mikeormsbee
  • FSU Profile: Florida State University Institute of Sports Sciences and Medicine

Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at Ketogenicgirl.com with the code VANESSA

Connect with Vanessa on Instagram @ketogenicgirl

Free High-Protein Keto Guide

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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.