#8 - Dr. Angela Reiersen: Depression, the Sigma 1 receptor and COVID-19
Release Date: 01/27/2021
#18: What COFFEE Does to Your Brain
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How Does Coffee Impact Your Brain? In this video we explore Brain Health, Alzheimer's Prevention, Mental Health, Mechanism, Dosing and Metabolism Check out the below blog for all the references Check out my newsletter! This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment.
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#17: How to Optimize Your Brain Cells
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In this episode, I discuss the four major types of brain cells, including neurons, microglia, astrocytes and oligodendrocytes, what they do and their role in brain health. I then discuss the research on what we can do to help optimize their function. Get my Free Guide: 11 Science-Backed Steps to Help Boost Memory and Prevent Dementia: Check out my free newsletter This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual...
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How Creatine Boosts Your Brain
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Creatine May Have Brain and Muscle Benefits: Initially popular among athletes for muscle growth and performance, creatine is now recognized for its potential positive effects on brain function. Naturally occurring in the body, especially in muscles, supplementation can significantly boost its levels. Enhancing Brain Function: Studies suggest that creatine supplementation increases brain creatine levels, which may counter mental fatigue and enhance brain energy metabolism. It's particularly noted for improving memory, especially in older adults, and may also boost intelligence and reasoning...
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Short #6: Alcohol and the Brain
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Alcohol use has been part of human culture for millennia. But modern research has revealed that ethanol may be a major risk for our brain health, and a potential brain booster. So, which is it? #alcohol #health #brainhealth #neuroscience Here's my full take: Want more brain science? Subcribe to my newsletter! This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment.
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Short #5: 4 Ways to Boost Mood and Help Prevent Depression
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We've all heard about exercise for preventing cardiovascular disease and weight gain. But where is the conversation about lifestyle modification to prevent conditions like depression? We have more than enough data to recommend diet, exercise, sleep and mindful interventions, and given the incredible damage to our health posed by conditions like depression, I think it's high time we give preventive mental health the attention it deserves. Here's the latest research on science-backed ways to boost mood and prevent depression that we should all be aware of. Note: The information presented above...
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Short #4: Plant Polyphenols for Brain Health
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There are thousands of molecules found in plants that are now known to impact everything from inflammation to the gut microbiome. They're called "polyphenols" and they may help explain why eating more whole plant foods is linked to better overall and brain health. For more, check out my website at Austinperlmutter.com
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Short #3: 3 Keys To Brain Foods For Brain Health
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All of us hear about “superfoods” and amazing vitamins and minerals that will fix everything from poor memory to our mood. But what does the science say about the traits of the top foods for brain health? Here are some top takeaways: • Food turns into the building blocks for our brains, so eating more high-quality foods may be a good recipe for a higher-quality brain • Foods that are rich in polyphenols and antioxidants may be especially excellent for brain wellness (these are found in higher levels in herbs and spices!) • Certain fats (omega-3s in particular) seem to be key to brain...
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Short #2: Brain Energetics, Mitochondrial Health, Metabolism and Lifestyle
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Get the Stuck Out Shorts Your brain uses more energy (by weight) than any other organ in the body. Your 86 billion neurons each contain up to a million mitochondria, responsible for generating power to keep your thoughts and consciousness running. When things go wrong, we may be at higher risk for brain diseases. So how does this complex system work, and what might we be able to do to improve it? Dr. Austin Perlmutter explains. For a comprehensive + user friendly take on brain energy, Dr. Chris Palmer's "Brain Energy" book is great! #metabolism #brainhealth #brain...
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Short #1: Sugar, Erythritol and Brain Health
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A recent study finds that erythritol may be bad for brain health. But how does sugar impact the brain overall, and what does the research say about sugar alternatives? Should we eat more honey? How does the microbiome factor in? For a nuanced conversation specific to the recent erythritol study, check out my blog at austinperlmutter.com/blog
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#16: Serotonin and Depression
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Depression is a worldwide issue experienced by hundreds of millions. For years, the main theory of what was going wrong in the brain focused on the neurotransmitter serotonin. This theory is called the serotonin hypothesis, and it's based on a number of data points. But recently, researchers have questioned whether serotonin plays a central or even a major role in depression at all. In this episode, I explore: -The current landscape of depression -The serotonin hypothesis and issues with it -The recent publication "The serotonin theory of depression: a systematic umbrella review of the...
info_outlineIn this episode I speak with Psychiatrist and researcher Dr. Angela Reiersen about her recent publication in JAMA, "Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19." We discuss:
-How she stays focused and gets things done
-Her research on fluvoxamine (an antidepressant) and COVID-19
-Why we need to go beyond the serotonin receptor in depression
-What the sigma 1 receptor is, and why it matters
-How sigma 1 agonists may reduce inflammation
-The need for a wider view of antidepressant mechanisms
-The importance of the connection between inflammation and depression
-How understanding newmolecular patterns of depression opens the door to treatment
-The importance of executive function interventions for children
-How sleep may improve executive functions