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#12 - Austin Perlmutter MD: Neuroplasticity, Depression, Psychedelics and Diet

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Release Date: 07/22/2021

BONUS: 3 Foods That Age Your Body and Brain show art BONUS: 3 Foods That Age Your Body and Brain

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Food influences cellular aging. Avoiding certain foods may help protect your brain and body from premature aging. I discuss the science around 3 of these foods.  Full article with references:  Check out my newsletter!  This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment.   

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Build Muscle to Boost Your Brain: Episode #20 show art Build Muscle to Boost Your Brain: Episode #20

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Groundbreaking research connects muscle mass to brain health. In this episode, you’ll discover how resistance training may help fight dementia and depression, why metabolic health starts with your muscles, and how specific nutrients and supplements can supercharge both body and mind. For my full free guide to this topic + all the studies I cited, along with a guide to top plant and animal based protein sources, head to Whether you're looking to future-proof your brain, optimize performance, or simply feel your best, this episode is your ultimate guide to harnessing the muscle-brain...

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#19: How Inflammation Affects Mental Health show art #19: How Inflammation Affects Mental Health

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Chronic inflammation is convincingly linked to higher risk of psychiatric disorders. But how, and what can we do about it? We cover: inflammatory cytokines, the inflammatory hypothesis of depression, key pathways acted on by inflammation in the brain and the role of pharmaceuticals and lifestyle factors in acting on inflammatory pathways related to mental health. Check out the below blog for all the references  Check out my newsletter! This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual...

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#18: What COFFEE Does to Your Brain show art #18: What COFFEE Does to Your Brain

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How Does Coffee Impact Your Brain? In this video we explore Brain Health, Alzheimer's Prevention, Mental Health, Mechanism, Dosing and Metabolism Check out the below blog for all the references Check out my newsletter! This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment.

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#17: How to Optimize Your Brain Cells show art #17: How to Optimize Your Brain Cells

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In this episode, I discuss the four major types of brain cells, including neurons, microglia, astrocytes and oligodendrocytes, what they do and their role in brain health. I then discuss the research on what we can do to help optimize their function. Get my Free Guide: 11 Science-Backed Steps to Help Boost Memory and Prevent Dementia: Check out my free newsletter This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual...

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How Creatine Boosts Your Brain show art How Creatine Boosts Your Brain

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Creatine May Have Brain and Muscle Benefits: Initially popular among athletes for muscle growth and performance, creatine is now recognized for its potential positive effects on brain function. Naturally occurring in the body, especially in muscles, supplementation can significantly boost its levels. Enhancing Brain Function: Studies suggest that creatine supplementation increases brain creatine levels, which may counter mental fatigue and enhance brain energy metabolism. It's particularly noted for improving memory, especially in older adults, and may also boost intelligence and reasoning...

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Short #6: Alcohol and the Brain show art Short #6: Alcohol and the Brain

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Alcohol use has been part of human culture for millennia. But modern research has revealed that ethanol may be a major risk for our brain health, and a potential brain booster. So, which is it? #alcohol #health #brainhealth #neuroscience Here's my full take: Want more brain science?  Subcribe to my newsletter!   This content is not intended to diagnose, treat, cure, or prevent disease. The information provided by this video should not be used as individual medical advice. You should always consult your healthcare provider for individual recommendations and treatment.

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Short #5: 4 Ways to Boost Mood and Help Prevent Depression show art Short #5: 4 Ways to Boost Mood and Help Prevent Depression

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We've all heard about exercise for preventing cardiovascular disease and weight gain. But where is the conversation about lifestyle modification to prevent conditions like depression? We have more than enough data to recommend diet, exercise, sleep and mindful interventions, and given the incredible damage to our health posed by conditions like depression, I think it's high time we give preventive mental health the attention it deserves. Here's the latest research on science-backed ways to boost mood and prevent depression that we should all be aware of. Note: The information presented above...

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Short #4: Plant Polyphenols for Brain Health show art Short #4: Plant Polyphenols for Brain Health

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There are thousands of molecules found in plants that are now known to impact everything from inflammation to the gut microbiome. They're called "polyphenols" and they may help explain why eating more whole plant foods is linked to better overall and brain health. For more, check out my website at Austinperlmutter.com

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Short #3: 3 Keys To Brain Foods For Brain Health show art Short #3: 3 Keys To Brain Foods For Brain Health

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All of us hear about “superfoods” and amazing vitamins and minerals that will fix everything from poor memory to our mood. But what does the science say about the traits of the top foods for brain health? Here are some top takeaways: • Food turns into the building blocks for our brains, so eating more high-quality foods may be a good recipe for a higher-quality brain • Foods that are rich in polyphenols and antioxidants may be especially excellent for brain wellness (these are found in higher levels in herbs and spices!) • Certain fats (omega-3s in particular) seem to be key to brain...

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More Episodes

Neuroplasticity is the brain's ability to change itself over the course of our lives. Impairments in neuroplasticity have been linked to depression, and many antidepressive therapies may actually work in part by boosting neuroplasticity. In this podcast we'll cover:

-How neuroplasticity changes over the lifespan

-The connection between impaired neuroplasticity and depression psychology

-How neuroplasticity maps onto imaging studies in depresssion

-How antidepressants may increase neuroplasticity 

-How psychedelics may augment neuroplasticity 

-How lifestyle modification including diet and sleep and exercise can improve neuroplasticity 

I will be updating the complete show notes on my website, austinperlmutter.com 

Noted article from Peter Attia: 

https://peterattiamd.com/my-nutritional-framework/