267 Muscle, Mitochondria and the Aging Brain: The Midlife Metabolism Reset with Dr. Elizabeth Goldspink

What if the fatigue, brain fog, and loss of strength many women experience after 50 are not simply hormonal, but reflect deeper shifts in metabolism, muscle, and mitochondrial function? In this insightful episode, Dr. Elizabeth Goldspink reframes midlife as a metabolic and neurological transition rather than a purely hormonal one. She explains how muscle acts as a longevity organ, how mitochondrial efficiency impacts both energy and cognition, and how targeted lifestyle and nutrition strategies can restore resilience. This empowering conversation offers practical, science-informed steps to help women take control of how they age.
Dr. Elizabeth Goldspink is a naturopathic doctor, women’s health researcher, and founder of Wellex. She has more than 16 years of clinical experience supporting women’s hormonal, metabolic, and immune health. Dr. Goldspink is a published author in peer-reviewed medical journals and has completed advanced training in mind-body medicine at Harvard University. Her work focuses on translating complex scientific research into practical, personalized health strategies. She has helped thousands of women restore energy, resilience, and long-term well-being. Her current focus is on evidence-based supplementation and metabolic health optimization for women in midlife and beyond.

Episode Timeline

00:00 – Welcome and introduction

02:30 – Midlife symptoms reframed: beyond hormones to metabolism and mitochondria

04:00 – Dr. Goldspink’s personal journey from marketing professional to naturopathic medicine

06:00 – Why brain fog, fatigue, and strength loss signal deeper biological shifts

08:00 – Muscle as a longevity organ and its role in metabolic and cognitive health

11:00 – The metabolic functions of muscle and the importance of myokines

13:30 – Resistance training and why lifting weights matters for women over 50

16:00 – Nutrition fundamentals: protein intake, glycemic stability, and whole foods

19:00 – Mitochondrial health and its connection to energy and cognition

22:00 – Practical strategies to optimize mitochondria without complex protocols

25:00 – Creatine explained: benefits for muscle, brain, and aging

29:00 – Real-world recovery and rebuilding strength after health setbacks

31:00 – Brain training, lifestyle habits, and community connection

33:00 – Managing stress, social media overload, and mental resilience

35:00 – Supplement strategy after 50: what to use and what to avoid

37:30 – Common mistakes: overuse of antioxidants and low-quality supplements

40:00 – The origin of Wellex and a mission to support underserved women’s health needs

43:00 – Practical daily steps to rebuild resilience and support healthy aging

45:00 – Wrap-up and key takeaways

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Connect with Dr. Elizabeth Goldspink

Website: https://wellex.co
Science-backed supplements for women’s metabolic and hormonal health
Information on clinical research and product formulations

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Call to Action

Find Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com (North America) or on Kindle

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