424: Antidepressants are Making me WORSE & Stress is Waking Me Up Early
The Hardcore Self-Help Podcast with Duff the Psych
Release Date: 12/14/2024
The Hardcore Self-Help Podcast with Duff the Psych
Dating and relationships have never been simple — but in today’s world of apps, algorithms, and endless options, it’s easy to feel overwhelmed and disconnected. In this episode, I speak with Dr. Justin Garcia, Executive Director of the Kinsey Institute, evolutionary biologist, sex researcher, and author of the upcoming book The Intimate Animal. We talk about what our biology can (and can’t) tell us about love and desire, how technology is reshaping intimacy, and why breakups can hit so hard. We also get personal — sharing stories about grief, recovery, non-monogamy, and navigating...
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In this episode, I’m honored to welcome Dr. Tracy Hicks, a dual-certified family and mental health nurse practitioner with over two decades of clinical experience—and a deeply personal connection to serious mental illness. Dr. Hicks is both the daughter of a parent and the mother of a child with schizophrenia spectrum disorders. Her perspective blends professional expertise with lived experience in a way that is both deeply compassionate and refreshingly practical. We talk about what schizophrenia really is (and isn’t), the impact of stigma on individuals and families, and the importance...
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In this episode, I share the absolute honest truth about my life at the moment. I also talk about my focus for this year, the phrases I can't get out of my head, and the things I'm grateful for from the last year. Let's do this. Got a question for the show? Email or head over the . Watch the video at Follow me on Instagram at and Facebook at More writings and additional podcast content over at
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In this deeply informative episode, I’m joined by licensed marriage and family therapist Melissa Mose, LMFT, who brings 30 years of clinical experience to the table and a unique approach to treating OCD by integrating Internal Family Systems (IFS) with traditional methods like Exposure and Response Prevention (ERP). Melissa shares how a personal experience—her daughter’s sudden-onset OCD—propelled her into the world of OCD treatment and changed the direction of her career. We talk through how OCD manifests, why traditional ERP can be both life-changing and difficult for people,...
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In this heartfelt and candid episode, I'm joined by Chef Chris Valdes—TV personality, cookbook author, and lifelong culinary artist—to talk about his powerful personal journey through the culinary world and the mental health struggles he’s faced along the way. From growing up in a Cuban restaurant in Miami to rising to national TV fame, Chris has seen both the bright lights and the dark corners of the kitchen. He shares stories of family, grief, hustle, and healing—including why he took a year off from everything to rediscover himself. Whether you're in food service, struggling with...
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Friends, welcome back to the Hardcore Self Help Podcast. This is my first interview back after a bit of a journey. I thought there was no better way to kick off this next phase of the podcast than by introducing you to a friend and brilliant human that I met in the interim. Dr. Amy Andrea Martinez is a professor of sociology with a focus on Chicano gang culture, incarceration, and abolition. She is a total badass, and she gets vulnerable about her experiences in this conversation. We discuss how her younger brother's arrest, the development of her identity as a Xicana woman, her experiences...
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Episode Summary: In this deeply personal solo episode, Dr. Duff returns to the mic after a hiatus to share what’s been going on behind the scenes with The Hardcore Self Help Podcast. He opens up about an almost-acquisition of the show by a larger mental health organization—a deal that initially looked promising but ultimately fell through. With transparency and vulnerability, Dr. Duff reflects on the emotional and professional impact of that experience, explains why the podcast paused, and announces the exciting new direction it’s headed in. What You'll Hear In This Episode: Why the...
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In this insightful interview, I’m joined by Marcia Bonato Warren, a trauma-informed body therapist, somatic counselor, interculturalist, and author. Marcia brings over 30 years of experience working with cross-cultural mental health, and she shares a powerful lens on how identity, culture, and trauma intersect in the body. Together, we explore the concept of embodied code switching, how our bodies carry cultural and ancestral imprints, and how healing often involves not just the mind, but movement, sensation, and deep awareness of the self. Marcia discusses her personal journey as a...
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In this episode, Dr. Duff takes on two powerful listener questions in a raw and compassionate Q&A format. The first question comes from a survivor of extensive childhood abuse, religious trauma, and complex family dynamics, who is wrestling with the decision of whether or not to publish a deeply personal memoir. Dr. Duff dives into the emotional, psychological, and ethical layers of this situation, offering validation, insight, and a heartfelt reminder that healing and storytelling can be acts of empowerment. The second question comes from a newly single parent facing feelings of...
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In this episode, I address two deeply personal listener questions that highlight the complex nature of anxiety and emotional healing in relationships. The first question comes from a listener who has struggled with anxiety for most of their life, recently facing severe limitations due to Generalized Anxiety Disorder and medication changes. We talk about the genetic components of anxiety, the risks of benzodiazepines in older adults, and the importance of advocating for the right care—even if that means seeking new providers or considering higher levels of treatment. The second question dives...
info_outlineIn this solo Q&A episode of the Hardcore Self Help Podcast (Episode 424), I tackle two listener questions that address challenging mental health scenarios. The first question delves into the concept of antidepressant-associated chronic irritable dysphoria (ACID), a proposed condition rather than a formally recognized diagnosis, and the potential long-term effects of antidepressants in the context of bipolar disorder. I break down the limited research behind ACID, emphasize the importance of comprehensive care, and acknowledge the frustration that can arise when medications seem to worsen symptoms instead of helping.
The second question focuses on waking up early with irritability and racing thoughts. I provide practical strategies like pre-bed journaling to offload worries, identifying actionable steps for lingering concerns, and creating a calming buffer before sleep. I also discuss the importance of reexamining one’s work environment, considering meaningful changes, and finding fulfillment outside of a stressful job. Throughout the episode, I offer insights on self-advocacy, exploring alternative treatments, and laying the groundwork to regain a sense of control in your daily life.
Chapters:
00:15 — Introduction: Needing More Questions & Holiday Scheduling
02:00 — ACID Explained: A Proposed Condition, Not a Formal Diagnosis
08:00 — Bipolar Disorder & Antidepressants: Complex Interactions and Research Gaps
11:00 — Frustration with Care: Inadequate Guidance and Long-Term Medication Issues
14:00 — Exploring Alternatives: Therapy, Lifestyle Changes, and Treatments Like TMS/Ketamine
21:00 — Morning Irritability: Unpacking Workplace Stress & Uncontrollable Factors
24:00 — Reevaluating Work: Finding Meaning Outside Employment and Considering Changes
27:00 — Pre-Bed Journaling: Offloading Worries, Identifying Action Steps, and Creating Buffers
30:00 — Final Thoughts: Gratitude, Year-End Plans, and Continuing the Journey
About the Podcast
I’m Dr. Robert Duff, a clinical psychologist and the host of the Hardcore Self Help Podcast. I’m here to demystify mental health, break down psychological concepts, and provide actionable advice without unnecessary jargon. Through expert interviews, listener Q&A, and relatable discussions, this podcast aims to help you live a healthier, more fulfilled life.
Connect With Me:
- Website: https://www.duffthepsych.com/
- Contact: https://www.duffthepsych.com/contact
- Email: duffthepsych@gmail.com
- Instagram: https://www.instagram.com/duffthepsych/
- YouTube: https://www.youtube.com/c/DuffThePsych
#MentalHealth #Antidepressants #Bipolar #WorkStress #Journaling #SleepHygiene #QandA #SelfHelp #Psychology