Health & Veritas
Howie and Harlan discuss the outlook for U.S. healthcare spending over the next five years, the state of seasonal and avian flu, and an expensive AI-based cardiac test. Show notes: Life expectancy and expenditures ACOs and cost savings World Prematurity Day AI concerns Bird flu Cardiology and AI Free speech and drug promotion Medicare premiums In the Yale School of Management’s , you’ll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's offers a rigorous public health education for working...
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Howie and Harlan are joined by Harvard internist Jerry Avorn to discuss his research on the pharmaceutical industry and his work promoting evidence-based prescribing. Harlan highlights new results from the American Heart Association meeting, including a one-time CRISPR-based therapy for high cholesterol; Howie reports on an outbreak of infant botulism. Show notes: Research from the American Heart Association Meeting Jerry Avorn Infant Botulism In the Yale School of Management’s , you’ll get a full MBA education in 22 months while applying new skills to your...
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Howie and Harlan are joined by cardiologist Ali Rahimi, the founder of ALYKA Health, which uses a personalized mobile app to help patients manage their heart health between doctor's visits. Harlan discusses new developments in GLP-1 obesity drugs, including untested microdose treatments; Howie reviews a landmark study investigating whether broad prostate cancer screening saves lives. Show notes: GLP-1 Drugs Ali Rahimi New Evidence on Prostate Cancer Screening and Breast Cancer Treatment In the Yale School of Management’s , you’ll get a full MBA education in 22...
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Howie and Harlan are joined by Nate Wood, a Yale School of Medicine internist and trained chef, to discuss his work combining lifestyle guidance with hands-on training in making healthy, tasty food. Harlan shares new guidance on what counts as a healthy blood pressure; Howie provides an update on rising health insurance costs. Links: Blood Pressure Obesity Drugs Culinary Medicine Health Insurance Costs .
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Howie and Harlan are joined by Yale School of Medicine immunologist Akiko Iwasaki, a leading authority on vaccines and long COVID. Harlan reflects on America’s crisis of trust in federal agencies; Howie provides some good news about bird flu. Links: Losing Trust Akiko Iwasaki Bird Flu .
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Howie and Harlan are joined by Rajlakshmi Krishnamurthy, the Yale School of Medicine's associate dean for population health, to discuss her work building holistic systems for care at multiple institutions. Harlan discusses healthcare headlines including the launch of "TrumpRX"; Howie reports on a new study taking a novel approach to understanding the impact of the COVID-19 vaccine. Links: Healthcare Headlines Population Health The COVID-19 Vaccine .
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Howie and Harlan discuss the roots of the crisis in emergency departments, the lack of oversight for hydration spas, new approaches in blood pressure treatment, an ingenious method to prevent malaria, and the CDC’s backward steps on vaccines. Links: Emergency Departments The Revolving Door Hydration Spas New Developments in Blood Pressure Treatment AI in Medicine: Doximity, OpenEvidence, and UpToDate Congenital syphilis MMR Vaccine Nobel Prizes and Science at Yale .
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Howie and Harlan are joined by Vanessa Cooper, a Yale School of Medicine neurologist, to discuss the causes of migraines and promising new treatments for the disorder. Harlan discusses his approach as a journal editor to the use of AI in academic writing; Howie reports on the premium tax credits for insurance purchased through Affordable Care Act exchanges that are at stake in the government shutdown. Links: The Government Shutdown Headaches ACA Tax Credits and the Government Shutdown .
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Howie and Harlan are joined by Kate Heilpern, president of Yale New Haven Hospital, to discuss the innovation and adaption needed to lead NewYork-Presbyterian Hospital through the worst of the COVID-19 pandemic, and how Yale New Haven Health structures itself to provide quality care across five hospitals. Harlan reflects on the many biotech startups emerging from Yale; Howie responds to the Trump administration's assertion of a link between acetaminophen and autism. Links: Biotech at Yale and Beyond . Kate Heilpern Tylenol and Autism .
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Howie and Harlan are joined by Yale School of Medicine geriatrician Barry Wu, who provides a framework for family caregivers and physicians to understand the needs of older adults. Harlan reports on Congress's shifting approach to funding research; Howie reflects on a survey showing that many college students believe that violence is an acceptable way to protest a campus speaker. Links: Congressional Directives on Funding Research Supporting Older Adults Violence and Speech ACA Subsidies .
info_outlineHowie and Harlan are joined by Stephen Waxman, a leading neurology researcher, to discuss the promise of new methods developed by his lab to treat the ravages of pain. Harlan talks about the importance of ratings for Medicare Advantage plans; Howie assesses two sobering new reports on the solvency of Medicare.
Links:
Harlan’s Section
Slides from Humana's Investor Day
"Humana’s cautious defense of Medicare Advantage"
"What Are the Medicare Star Ratings?"
"Early analysis: How health plans fared in the 2025 Medicare Advantage star ratings"
Interview with Dr. Waxman
"F.D.A. Approves Drug to Treat Pain Without Opioid Effects"
"A brief historical perspective: Hodgkin and Huxley"
Nobel Prize: “Speed read: Signal to charge"
"Targeting a Peripheral Sodium Channel to Treat Pain"
Girl with the Dragon Tattoo: "Ronald Niedermann"
"Peripheral Sodium Channel Blocker Could Revolutionize Treatment for Nerve Pain"
"Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain"
"A historical perspective on the discovery of statins"
"The Two Sides of NaV1.7: Painful and Painless Channelopathies"
"Dr. Stephen Waxman awarded Sharpey-Schafer Prize for pain research"
"Scientists Identify Method to Study Resilience to Pain"
"Chasing the genes behind pain"
"Stephen Waxman: pioneer in axons, their disorders, and pain"
"I Feel Like I’m Burning Alive. It’s Hard for People to Believe Me"
"‘How badly does it hurt?’ Challenges of measuring pain in clinical trials"
Howie’s Section
"2025 Medicare Trustees Report"
"Analysis of the 2025 Medicare Trustees' Report"
"Medicare gets a big (unofficial) surprise: a 17-year extension on when it’ll run dry"
"Evan Sussman: Expanding Access to Fertility Drugs"
"Trump gives major lift to 2026 Medicare Advantage payments"
"June 2025 Report to the Congress: Medicare and the Health Care Delivery System"
"How UnitedHealth turned a questionable artery-screening program into a gold mine"
"From boom to bitcoin: A device maker’s surprising pivot amid a Medicare crackdown"
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