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Eric Topol: The Keys to Healthy Aging

Health & Veritas

Release Date: 09/11/2025

An Ongoing Conversation about Health and Healthcare show art An Ongoing Conversation about Health and Healthcare

Health & Veritas

In the 200th episode of Health & Veritas, Harlan offers end-of-the-year reflections on medicine drawn from his editor’s notes in JACC (the Journal of the American College of Cardiology), and Howie provides updates on gun violence, flu, measles, and the health benefits of yoga. Show notes: Editor’s notes by Harlan Krumholz Gun violence, flu, and measles The benefits of yoga In the Yale School of Management’s , you’ll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's  offers a rigorous public...

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Howie and Harlan discuss the outlook for U.S. healthcare spending over the next five years, the state of seasonal and avian flu, and an expensive AI-based cardiac test.  Show notes: Life expectancy and expenditures ACOs and cost savings World Prematurity Day AI concerns Bird flu   Cardiology and AI Free speech and drug promotion Medicare premiums In the Yale School of Management’s , you’ll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's offers a rigorous public health education for working...

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Howie and Harlan are joined by Yale School of Medicine immunologist Akiko Iwasaki, a leading authority on vaccines and long COVID. Harlan reflects on America’s crisis of trust in federal agencies; Howie provides some good news about bird flu.  Links: Losing Trust Akiko Iwasaki Bird Flu .

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Howie and Harlan are joined by Rajlakshmi Krishnamurthy, the Yale School of Medicine's associate dean for population health, to discuss her work building holistic systems for care at multiple institutions. Harlan discusses healthcare headlines including the launch of "TrumpRX"; Howie reports on a new study taking a novel approach to understanding the impact of the COVID-19 vaccine. Links: Healthcare Headlines Population Health The COVID-19 Vaccine .

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More Episodes

Howie and Harlan are joined by physician, scientist, and author Eric Topol to discuss his new book, Super Agers: An Evidence-Based Approach to Longevity; the potential of individualized polygenic risk scores; and the dangers of the protein craze.

Links:

Health & Veritas Ep. 58: Dr. Eric Topol: Pushing Medicine into the Future

Eric Topol: Super Agers: An Evidence-Based Approach to Longevity

Eric Topol: “The Drivers of Age-Related Diseases”

Eric Topol: “A Review of Outlive

Eric Topol, Ground Truths podcast: “Peter Attia: Our conversation about his hit book Outlive, Medicine 3.0, promoting healthspan, GLP-1 drugs and more”

Eric Topol: The Creative Destruction of Medicine

Eric Topol: The Patient Will See You Now

Eric Topol: Deep Medicine

Eric Topol: “Our Preoccupation With Protein Intake”

The Daily podcast: “How America Got Obsessed with Protein”

“High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy”

“Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk”

“5 Takeaways From Kennedy’s Senate Hearing”

Eric Topol on the Dr. Hyman Show: “How AI Could Change Your Next Doctor Visit Forever!”

Eric Topol: “The Business of Promoting Longevity and Healthspan”

The Age of the Infovore: Succeeding in the Information Economy

Eric Topol, Ground Truths podcast: “Tyler Cowen: The Prototypic Polymath”

“How a scientist who studies ‘super agers’ exercises for a longer life”

Eric Topol: “Our Sleep, Brain Aging, and Waste Clearance”

“Alzheimer's genes: Are you at risk?”

Eric Topol: “The Breakthrough Blood Test for Alzheimer's Disease”

Eric Topol: “Predicting and preventing Alzheimer’s disease”

Eric Topol: “The personal and clinical utility of polygenic risk scores”

Eric Topol: “Polygenic Risk Scores: Ready for Prime Time?”

“Physical Activity Among Adults Aged 18 and Over: United States, 2020”

“Wellderly” studies

Eric Topol: “What My Two 98-Year-Old Patients Taught Me About Longevity”

Eric Topol, Ground Truths podcast: “Mike Osterholm & Eric Topol Discuss The Big One book”

“Hypertrophic Cardiomyopathy”

Eric Topol: “Lithium and Its Potential Protection from Alzheimer's Disease”

Eric Topol: “High-performance medicine: the convergence of human and artificial intelligence”


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