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Immune Booster #22 T cell signaling and selection with Leslie Berg

Release Date: 02/10/2026

Immune

Immune discusses how tattoo ink accumulates in lymph nodes, promotes inflammation and influences response to two different vaccines. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode IL-9, CD8 cells and vaccines Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Immune Booster 23: Critical windows during immune system development with Anna Beaudin

Immune

Anna Beaudin from University of Utah talks about the key thread of her career, development, and how that influences her research on the events happening during critical prenatal windows shapes everything from the developing immune system to hearing loss. Host: Guest Subscribe (free): , , Become a of Immune! Links for this episode at University of Utah PhD work on Postdoc work on and hematopoietic stem cell development on postnatal immunity Early life inflammation and Time stamps by . Thanks! Music by . Logo image...

Immune Booster #22 T cell signaling and selection with Leslie Berg

Immune

Leslie Berg talks about her career studying T cell receptor signaling, T cell development, and the importance of mentors in her career. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode at University of Colorado Anschutz TCR thresholds and ITK (PNAS) Review on TCR signaling (Nat Immunol) Generation of (Mol Cell Bio) in TCR transgenic mice (Nature) Thymic n TCR transgenic mice (Cell) Berg information Time stamps by . Thanks! Music by . Logo image by Send...

Immune 100: Immune turns 100!

Immune

The whole Immune gang gathers with special guests Gretchen Diehl and Shruti Naik at The Incubator with an audience to celebrate the 100th episode. Hosts: , , and Guests: and Subscribe (free): , , Become a of Immune! Links for this episode Diehl: Gut development (Nature 2021) Diehl: Bacteria-i (Gut Microbes 2022) Diehl: Microbiota, and colitis (Gut Microbes 2022) Diehl: E. coli-activated inflammation (Cell Rep 2025) Naik: skin inflammation (Science 2012) Naik: IL-17...

Immune Booster 21: Origins of antigen receptors with David Schatz

Immune

David Schatz talks about his discovery of Rag genes that are critical for antigen receptor development and how that discovery depended on taking high risks and using approaches that everyone thought could never work. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Tin non-lymphoid cells (Cell 1988) Identification of (Cell 1989) (Semin Immunol 2004) Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv...

Immune 99: A Nobel for immune tolerance

Immune

The Immune team discusses the groundbreaking discoveries of regulatory T cells, which was the topic of the 2025 Nobel Prize in Physiology or Medicine. Hosts: , , and Subscribe (free): , , Become a of Immune! Links for this episode Sakaguchi lab (Science 2003) Brunkow and Ramsdell mutation (Nature 2001) on Treg discoveries Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed...

Immune Booster 20: Lipid GPS for T cells with Susan Schwab

Immune

Susan Schwab talks about how she got the research bug, bugs she ate, and her research on how the lipid S1P helps T cells decide- should I stay or should I go. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Schwab lab Monocytes to regulate T cell movement and immune cell migration Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Immune 98: T cells on the brain

Immune

Immune discusses cross-reactive antibodies to avian influenza neuraminidases and a role for gut-derived T cells in the brain to regulate eating behavior. Hosts: , , , and Subscribe (free): , , Become a of Immune! Links for this episode Antibody H5N1 (Cell Host Microbe, 2025) Gut-derived (Nature, 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical...

Immune Booster 19: Virus-immune Tug-of-war with Kristian Andersen

Immune

Kristian Andersen from Scripps Research Institute joins Cindy to talk about how he got interested in virus evolution, how the immune system drives viral adaptation, and what we can learn from this research to better prepare us for the next pandemic. Host: Guest: Subscribe (free): , , Become a of Immune! Links for this episode Andersen Perspective on of virus emergence Kristian’s appearance Time stamps by . Thanks! Music by . Logo image by Send your immunology questions and comments...

Immune 97: Bystander B cells go bananas

Immune

Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis. Hosts: and Subscribe (free): , , Become a of Immune! Links for this episode Somatic B cells (Immunity 2025) Dysfunctional vaginosis (J Clin Invest 2025) Time stamps by . Thanks! Music by Tatami. Immune logo image by Send your immunology questions and comments to immune@microbe.tv Information...

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Leslie Berg talks about her career studying T cell receptor signaling, T cell development, and the importance of mentors in her career.

Host: Cindy Leifer

Guest: Leslie Berg

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Links for this episode

MicrobeTV Discord Server
Berg lab at University of Colorado Anschutz
TCR thresholds and ITK (PNAS)
Review on TCR signaling (Nat Immunol)
Generation of TCR transgenic mice (Mol Cell Bio)
T cell negative selection in TCR transgenic mice (Nature)
Thymic exit of mature T cells in TCR transgenic mice (Cell)
AAI past president Berg information
Time stamps by Jolene Ramsey. Thanks!

Music by Tatami.
Logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv

Information on this podcast should not be construed as medical advice.

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