Entactogens, MDMA, and Bringing New Love Drugs To Market | Matthew Baggott ~ ATTMind 177
Release Date: 06/02/2023
Adventures Through The Mind
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Matthew Baggott discusses the phenomenon of "losing the magic" with MDMA use, where frequent users experience diminishing therapeutic effects over time, likely due to decreased serotonin transporters in the brain; as well as N-Acetyl Cysteine (NAC) supplementation as a potential avenue for getting the magic back. ... This is a clip from 'Entactogens, MDMA, and Bringing New Love Drugs To Market | Matthew Baggott ~ ATTMind Podcast 177' FULL INTERVIEW SUPPORT THE PODCAST 🥰 Other options Toss me a tip on PayPal: Buy some merchandise: More Options: ▷...
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EPISODE DETAILS Nicholas P. Money is Professor of Biology and Western Program Director at Miami University in Oxford, Ohio. He is an international expert on fungal biology and author of popular science books that celebrate the microbial world including his most recent, Molds, Mushrooms, and Medicines: Our Lifelong Relationship with Fungi (2024) He joins us on the podcast to deep dive into the biology, ecology, and intelligence of fungi. We discuss the body and life cycle of mushrooming fungi; the shape and behaviour of mycelium; how fungi are more similar to humans than they...
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Dr. Oliver Grundmann talks about kratom's adverse effects, including addiction risks, constipation, nausea, and potential liver toxicity. He emphasizes that liver concerns are rare, dose-dependent, and often complicated by other factors like alcohol use, while stressing the need for better product regulation. ... This is a clip from 'All About Kratom | Dr. Oliver Grundmann'- ATTMind Podcast Episode 121 Watch in Video here: Full Episode and show notes here: SUPPORT THE PODCAST Become a member of my Patreon: Toss me a tip on...
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This episode features an interview with Jeffery Lando, an experienced filmmaker who recently directed the psychedelic-themed movie "Lissa's Trip". Our discussion explores the intersection of psychedelics, artificial intelligence, and filmmaking. We discuss into how Lando used AI and other emerging technologies to create the visual effects for his film, producing some of the best LSD-like psychedelic visuals and audio that I have personally seen in a movie. We also discuss the potential impacts of AI on the film industry and creative processes more broadly. We explore ideas around personal...
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Adventures Through The Mind is an interview-based podcast focusing on psychedelics. It is hosted by Canadian author and public educator, James W. Jesso. Thanks for listening. Enjoy. SUPPORT THE PODCAST Become a member of my Patreon: Toss me a tip on PayPal: Toss my a Tip on Ko-Fi: Buy some merchandise: More Options: Newsletter: Telegram Channel: Various Podcast Subscribe Options and Social Media Handles:
info_outlineThis episode features Matthew Baggott of Tactogen Inc. and will explore entactogens, which are drugs like MDMA, 2C-B, and Methalone.
We start with setting a basic framework for what an entactogen is and a few example drugs, before exploring the complexities in their various effects, mechanisms of action, and both the legislative and technical process of the development of novel or new entactogenic drugs.
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For links to Baggott's work, full show notes, and a link to watch this episode in video, head to bit.ly/ATTMind177
*** FULL TOPICS BREAKDOWN BELOW**
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Episode Breakdown
- (0:00) Opening
- (2:44) Guest Bio
- (4:06) Patreon thanks | Support The Show
- (5:42) Interview begins
- (6:31) What is an entactogen and what does it do? | The difference between entactogens and psychedelics
- (8:37) A short discussion about 2C-B
- (11:47) A list of different entactogens
- (15:30) r-MDMA vs s-MDMA
- (19:48) Methalone, aka bk-MDMA
- (21:52) 3-MMC and 4-MMC: patents, development, and legality
- (23:13) Why Schedule 1 makes drug development difficult
- (25:02) The qualities they are trying to design OUT of new entactogen drugs (pt1)
- (26:31) “The loss of magic” with MDMA
- (33:11) Serotin transporters and MDMA neuro-oxidization
- (36:27) Using NAC to bring back the MDMA magic | enhanced plasticity, antioxidants, and homeostasis
- (44:13) The qualities they are trying to design OUT of new entactogen drugs (pt2)
- (48:52) Why we need “take home” entactogenic drugs
- (53:20) Can a drug still be medicine if it’s fun, too?
- (58:13) The process of justifying off-label MDMA prescriptions
- (1:03:01) Will there be a moral backlash against the development of “good feel” drugs?
- (1:11:10) The negative social consequences of prohibitionist law enforcement
- (1:15:58) We can’t just give people psychedelics and expect society will get better
- (1:18:46) Problematic moves in the psychedelic biotech industry
- (1:25:01) Psychedelic Patent Trolling
- (1:32:15) How Tactogen is trying to give back to psychedelic users
- (1:44:16) Increasing access to health care, not just to psychedelic substances
- (1:49:40) Follow-up link and contact details
- (1:51:25) closing