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Adjuvant Durvalumab and the Future of Early-Stage NSCLC

Journal of Clinical Oncology (JCO) Podcast

Release Date: 05/14/2026

Adjuvant Durvalumab and the Future of Early-Stage NSCLC show art Adjuvant Durvalumab and the Future of Early-Stage NSCLC

Journal of Clinical Oncology (JCO) Podcast

Guest Dr. Glenwood Goss discuss JCO article, "" and the implications of minimal residual disease,  results regarding the efficacy of immunotherapy in the adjuvant setting, and the evolving strategies for patient care in lung cancer treatment.

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JCO Article Insights: LEAP-010 Study in Recurrent/Metastatic Head and Neck Cancer show art JCO Article Insights: LEAP-010 Study in Recurrent/Metastatic Head and Neck Cancer

Journal of Clinical Oncology (JCO) Podcast

Host Jake New summarizes and offers insights into the JCO article by Licitra et al., "Pembrolizumab With or Without Lenvatinib as First-Line Therapy for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Phase III LEAP-010 Study."

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Infections in Two Diet Strategies in HSCT and Leukemia Patients show art Infections in Two Diet Strategies in HSCT and Leukemia Patients

Journal of Clinical Oncology (JCO) Podcast

Guest Dr. John Wingard and host Dr. Davide Soldato discuss JCO article, "," the reason behind the trial, its design, methodology, results, and the implications for future dietary approaches in hematology.

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JCO Article Insights: ctDNA in DLBCL - Ready for Prime Time? show art JCO Article Insights: ctDNA in DLBCL - Ready for Prime Time?

Journal of Clinical Oncology (JCO) Podcast

In this episode of JCO Article Insights, host Dr.  Ash Gurumurthi summarizes JCO articles, "" and " " TRANSCRIPT Ash Gurumurthi: Hi and welcome to . I'm your host, Ash Gurumurthi, and today we will be discussing two articles, both published in the , on the real-world utility of circulating tumor DNA (ctDNA) MRD in newly diagnosed large B-cell lymphoma. The first study is the article "" by Dr. Joanna Krupka and colleagues in the United Kingdom. For the sake of convenience, I'll refer to this as the DIRECT study. The second study is "" by Dr. Steven Wang and colleagues in the Netherlands,...

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The CISTO Study: Radical Cystectomy or Bladder-Sparing Therapy for Recurrent NMIBC show art The CISTO Study: Radical Cystectomy or Bladder-Sparing Therapy for Recurrent NMIBC

Journal of Clinical Oncology (JCO) Podcast

Guest Dr. John Gore and host Dr. Davide Soldato discuss JCO article, "," which compares radical cystectomy and bladder sparing therapy for patients with recurrent high-grade non-muscle invasive bladder cancer. Dr. Gore and Dr. Soldato focus on the study's patient-centered approach, eligibility criteria, and quality of life after treatment. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Davide Soldato: Hello and welcome to , the podcast where we sit down with authors from some of the latest articles published in the . I am your host, Dr. Davide...

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JCO Article Insights: Atezolizumab, Bevacizumab, and Non-Platinum Chemotherapy for PROC show art JCO Article Insights: Atezolizumab, Bevacizumab, and Non-Platinum Chemotherapy for PROC

Journal of Clinical Oncology (JCO) Podcast

In this episode of JCO Article Insights, host Dr. Melis Canturk summarizes the article, “” by Harter et al. TRANSCRIPT Melis Canturk: Hello, and welcome to the . I'm your host, Melis Canturk, and today we will be discussing the article, “.” While integrating immune checkpoint inhibitors has revolutionized the treatment of various gynecologic cancers, these agents have historically shown limited single agent activity in ovarian cancer. Despite a strong biological rationale for combining immunotherapy with chemotherapy and bevacizumab to enhance T-cell infiltration and normalized...

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JCO Article Insights: Ribociclib Plus Letrozole in Recurrent LGSOC: GOG 3026 show art JCO Article Insights: Ribociclib Plus Letrozole in Recurrent LGSOC: GOG 3026

Journal of Clinical Oncology (JCO) Podcast

In this episode of JCO Article Insights, host Dr. Melis Canturk summarizes the article, "" by Slomovitz et al.  TRANSCRIPT Melis Canturk: Hello, and welcome to . I'm your host, Melis Canturk, and today we will be discussing the article, "." Building on the fact that more than 95% of low-grade serous carcinoma are estrogen receptor positive and often exhibit abnormalities in the CDK4/6 signaling pathway, researchers launched the GOG 3026 trial. This study investigated the effectiveness of pairing the CDK4/6 inhibitor ribociclib with letrozole, an aromatase inhibitor, adapting a...

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NCI Working Group on Biochemically Recurrent Prostate Cancer show art NCI Working Group on Biochemically Recurrent Prostate Cancer

Journal of Clinical Oncology (JCO) Podcast

Host Dr. Davide Soldato and guests Dr. David Einstein and Dr. Ravi Madan discuss JCO article, "," underscoring the need for a consensus on clinical trial designs implementing novel endpoints in this population and the importance of PSA doubling time as a prognostic factor, with an emphasis on treatment de-escalation to limit toxicity and improve patient outcomes. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Davide Soldato: Hello and welcome to , the podcast where we sit down with authors from some of the latest articles published in the . I am your...

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Association Between EOL SACT and Healthcare Utilization show art Association Between EOL SACT and Healthcare Utilization

Journal of Clinical Oncology (JCO) Podcast

Host Dr. Davide Soldato and guests Dr. Kerin Adelson and Dr. Maureen Canavan discuss JCO article ",” highlighting adverse outcomes for patients who receive any type of systemic anticancer therapy(SACT) at EOL (end of life) and the need for better communication between oncologists and patients regarding expected risk and benefits of such treatments to properly align goals-of-care. TRANSCRIPT Dr. Davide Soldato: Hello and welcome to , the podcast where we sit down with authors from some of the latest articles published in the . I am your host, , medical oncologist at Ospedale San Martino in...

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Milan Consensus Endpoints for Bladder Preservation in MIBC show art Milan Consensus Endpoints for Bladder Preservation in MIBC

Journal of Clinical Oncology (JCO) Podcast

Guests Dr. Andrea Necchi, Dr. Ashish Kamat and host Dr. Davide Soldato discuss JCO article ",” focusing on the evolving treatment landscape of MIBC (muscle-invasive bladder cancer) and the need to properly design novel trials investigating non-operative management while including the incorporation of biomarkers and patient perspectives in clinical trials. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Davide Soldato: Hello and welcome to , the podcast where we sit down with authors from some of the latest articles published in the . I am your...

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Guest Dr. Glenwood Goss discuss JCO article, "Adjuvant Durvalumab in Completely Resected Early-Stage Non-Small Cell Lung Cancer" and the implications of minimal residual disease,  results regarding the efficacy of immunotherapy in the adjuvant setting, and the evolving strategies for patient care in lung cancer treatment.

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