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JCO at ASCO 2026: Individualized Neoantigen Therapy Plus Pembrolizumab in Melanoma

Journal of Clinical Oncology (JCO) Podcast

Release Date: 06/01/2026

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Journal of Clinical Oncology (JCO) Podcast

What pCR rates can be achieved with neoadjuvant THP, and which patients are most likely to respond? Host Dr. Davide Soldato interviews Dr. Nadine Tung on her article, “.” They examine differences in pCR by estrogen receptor status and the clinicopathologic and HER2DX features associated with response, while considering how these findings may inform treatment personalization as the trial’s 3-year recurrence-free survival data mature.

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Host Dr. Jake New interviews Dr. Makoto Tahara about the JCO article "." They discuss clinical considerations for individualizing treatment schedules and impact of treatment schedule on toxicity and patient quality of life.

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How does dexrazoxane affect left ventricular function over time after doxorubicin treatment for childhood cancer? Host Dr. Davide Soldato sits down with Dr. Erin Mobley and Dr. Eric Chow to discuss their article, “” They examine the longitudinal echocardiographic findings, the durability of cardioprotection, and how dexrazoxane exposure might eventually inform cardiomyopathy risk stratification and

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Guest Dr. Vedang Murthy and host Davide Soldato discuss JCO article, "" and delve into trial design, results, clinical implications, and future directions in bladder cancer treatment.

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In this episode of JCO Article Insights, host Ash Gurumurthi summarizes the article "," by Mehta-Shah and colleagues.

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Guests Dr. Elise Park, Dr. Jamie Ostrov and host Dr. Davide Soldato discuss JCO article "" and their groundbreaking trial on virtual tobacco cessation treatment for cancer patients in community settings. LINK TO FULL TRANSCRIPT

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Guests Akash Kulgod and Dr. Sanjeev Kulgod and host Dr. Davide Soldato discuss JCO article, "" and the innovative breath-based canine olfaction for multi-cancer detection in low-resource settings, the Bayesian modeling integration, and future prospects for scalable, non-invasive cancer screening methods.

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JCO at ASCO 2026: Individualized Neoantigen Therapy Plus Pembrolizumab in Melanoma show art JCO at ASCO 2026: Individualized Neoantigen Therapy Plus Pembrolizumab in Melanoma

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JCO Editorial Fellow Dr. Ash Gurumurthi and JCO Associate Editor Dr. Grant McArthur discuss the ASCO 2026 Simultaneous Publication paper "."

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JCO Podcast host Dr. Davide Soldato and JCO Associate Editor Dr. Dr. Eileen M. O’Reilly discuss the ASCO 2026 Simultaneous Publication paper "."

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JCO Editorial Fellow Dr. Yuvanesh Vedaraju and JCO Associate Editor Dr. Kathy Miller discuss the ASCO 2026 Simultaneous Publication paper "."  

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JCO Editorial Fellow Dr. Ash Gurumurthi and JCO Associate Editor Dr. Grant McArthur discuss the ASCO 2026 Simultaneous Publication paper "Intismeran Autogene Plus Pembrolizumab Versus Pembrolizumab Alone in High-Risk Resected Melanoma: 5-Year Update of the Randomized Phase 2b KEYNOTE-942 Study."

LINK TO FULL TRANSCRIPT