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STOP Using Ozempic (GLP1's) the Wrong Way: Top Tips for Crushing It on Weight Loss Peptides with Karen Martel and Jessica Brennan

The Hormone Solution Podcast with Karen Martel

Release Date: 08/23/2025

Reverse Dieting, Metabolic Recovery, and the Real Way to Fix Your Fat Loss Plateaus with Philip Pape show art Reverse Dieting, Metabolic Recovery, and the Real Way to Fix Your Fat Loss Plateaus with Philip Pape

The Hormone Solution Podcast with Karen Martel

Are you struggling with weight loss despite following a strict diet? Ever wondered if eating more could actually help you lose weight? Join us in this episode as we dive into the intriguing world of reverse dieting and metabolic recovery with Philip Pape, a high-performance nutrition coach. Do you know about GLP-1 medications and their revolutionary role in weight management? Are you curious about how to optimize your metabolism and finally break through those frustrating weight loss plateaus? Philip unpacks these groundbreaking topics, providing you with the knowledge to transform your...

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Tesofensine: The Next Big Weight Loss Compound That Boosts Dopamine, Burns Fat and Lights up the Midlife Brain show art Tesofensine: The Next Big Weight Loss Compound That Boosts Dopamine, Burns Fat and Lights up the Midlife Brain

The Hormone Solution Podcast with Karen Martel

Ready to hear about a new revolutionary weight loss strategy tailored for midlife women? Ever wondered how cutting-edge peptides and hormones can transform your wellness journey? This episode dives deep into the world of tesofensine, a fascinating compound originally researched for Parkinson's and Alzheimer's, now making waves in weight management. What makes tesofensine a potential game-changer for women experiencing hormonal shifts during perimenopause and menopause? How does it work to enhance neurotransmitter balance and boost metabolic health? Discover the unexpected benefits and...

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The Forgotten Molecule That 98% of Women Lose in Midlife—And How It Can Revive Your Libido, Energy & Glow with Cathy Eason show art The Forgotten Molecule That 98% of Women Lose in Midlife—And How It Can Revive Your Libido, Energy & Glow with Cathy Eason

The Hormone Solution Podcast with Karen Martel

Curious about the molecule that's been dubbed the "molecule of energy?” Ever wonder how it impacts women's health, especially during midlife? Join us as we dive into the world of nitric oxide with Cathy Eason, Chief Science Officer at Berkeley Life. Discover why this often-overlooked molecule might be the missing piece in your health puzzle. What if your midlife vitality could be revitalized with a simple molecule? How does nitric oxide influence libido, heart health, and even skin vitality? Cathy debunks myths and uncovers the hidden connections between nitric oxide and hormones like...

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Menopause Besties Q&A: Hormone Testing, Progesterone Truths, Late-Start HRT & More with Zora Benhamou show art Menopause Besties Q&A: Hormone Testing, Progesterone Truths, Late-Start HRT & More with Zora Benhamou

The Hormone Solution Podcast with Karen Martel

Are you curious about the mysteries of menopause and how to navigate this transformative life stage with confidence? In this Q&A episode, we sit down with Zora Benhamou to answer all your burning questions about hormone management and replacement therapy. How do you know if your hormone levels are optimal, and what can you do if they're not? Ever wondered about the truths and myths surrounding progesterone? Zora shares invaluable insights into the world of hormone testing and what those numbers really mean for your health. Why is it crucial to consider both estradiol and progesterone, and...

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Beyond Estrogen & Progesterone: The Hidden Hormones That Transform Aging show art Beyond Estrogen & Progesterone: The Hidden Hormones That Transform Aging

The Hormone Solution Podcast with Karen Martel

Learning how to harness the power of the lesser-known hormones is an important part in your overall hormone health. Dr. Thierry Hertoghe joins today to discuss some of these hormones and how he uses them in his medical practice. Dr. Hertoghe is a hormone doctor in Brussels, Belgium and is an international authority on medical hormone and nutrition therapies. He believes aging is due to hormone, lifestyle, and nutrition deficiencies and shares his expertise with us today. In this episode: Clarifying the myths about growth hormone. How much younger you can look and feel with hormone therapy....

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This Is Your Bones on HRT:  How Estrogen, Progesterone & Testosterone Protect—and Why Cycling HRT May Be the Secret to Stronger Bones with Dr. Doug Lucas show art This Is Your Bones on HRT: How Estrogen, Progesterone & Testosterone Protect—and Why Cycling HRT May Be the Secret to Stronger Bones with Dr. Doug Lucas

The Hormone Solution Podcast with Karen Martel

Are your bones as strong as they could be? In this episode, Dr. Doug Lucas, a renowned orthopedic surgeon turned hormone specialist, dives deep into the world of bone health. Have you ever wondered how hormone replacement therapy impacts your bones? Discover why Dr. Doug believes osteoporosis is neither inevitable nor irreversible. Why should you be concerned about your bone health, especially as you age and explore HRT? Dr. Doug shares alarming statistics about fractures and mortality rates, especially among postmenopausal women. What role do hormones like estrogen and testosterone play in...

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Irregular Periods in Perimenopause:  What’s Normal, What’s Not, and How HRT Really Plays In show art Irregular Periods in Perimenopause: What’s Normal, What’s Not, and How HRT Really Plays In

The Hormone Solution Podcast with Karen Martel

Are you baffled by the rollercoaster of irregular periods during perimenopause? Wondering why your cycle seems to have a mind of its own, even when you're on hormone replacement therapy? This episode is your guide to navigating the tumultuous terrain of perimenopausal hormonal changes. What role do key hormones like progesterone, estradiol, and FSH play in this chaotic phase? Can herbal remedies truly aid in balancing your hormones and easing your symptoms? Discover how understanding your body's signals can empower you through this transition. How do bioidentical hormones help manage these...

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The Period Brain: PMS, PMDD & the Scary Truth About Birth Control show art The Period Brain: PMS, PMDD & the Scary Truth About Birth Control

The Hormone Solution Podcast with Karen Martel

Curious about how your hormones influence your mood, libido, and relationships? Dr. Sarah Hill, a leading evolutionary psychologist, is here to unravel the mysteries of women's hormonal cycles and their profound impact on emotional and sexual well-being. Are you ready to challenge the conventional wisdom around PMS and PMDD? Ever wondered why your sexual desire seems to fluctuate throughout the month? Dr. Hill delves into the natural ebb and flow of women's libido and how understanding these cycles can enhance intimacy. Can knowing more about your hormones improve your relationship dynamics?...

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Beauty Without Toxins: The Alitura Story with Andy Hnilo show art Beauty Without Toxins: The Alitura Story with Andy Hnilo

The Hormone Solution Podcast with Karen Martel

How did a near-fatal accident could lead to a groundbreaking skincare revolution? Discover Andy Hnilo’s inspiring journey from tragedy to triumph as he transforms adversity into Alitura’s luxurious, natural skincare solutions. What are the secrets behind his success? Have you ever wondered why ingredient authenticity is crucial in skincare? Dive into the meticulous world of sourcing the finest ingredients from across the globe. How does Andy ensure each product meets the highest standards, and what role does nutrition play in achieving glowing skin? Is it possible to enhance your beauty...

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Hot Topics in Menopause: Round Table with The Meno Besties show art Hot Topics in Menopause: Round Table with The Meno Besties

The Hormone Solution Podcast with Karen Martel

Are you ready to unravel the mysteries of menopause with a sprinkle of fun and a dose of expertise? Join us for a lively roundtable where Dr. Fiona Lovely, Zora Benhamou and Karen debunk myths and bring clarity to this transformative life stage. Ever wondered why menopause is often compared to "reverse puberty," or how unresolved childhood trauma might affect hormonal health? Have you ever questioned if stress could be accelerating your journey into perimenopause? This episode dives into unexpected challenges women face in their late 30s and beyond. What’s the real story behind hormone...

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More Episodes

Jessica Brennan, started in the fitness industry 10 years ago as a fitness instructor and personal trainer, realized early on that achieving health goals went beyond physical activity. This realization led Jessica to pursue certifications in nutrition, hormone specialist, and gut health specialist, aiming to address health challenges holistically.

Working closely with Karen at Hormone Solutions, Jessica is dedicated to sharing her expertise with women globally. Her areas of expertise include bodybuilding, women’s hormone health, personalized nutrition, peptide therapy, and chronic illness management.

Jessica is with me this time to discuss our one-year anniversary of being on weight loss peptides. We also created our weight loss peptide group about a year ago which, in addition to our own experiences, has provided us many different points of view on the ups and downs that members face. We’ll share personal stories and lessons learned from our community of over 200 members, discussing the use of GLP-1 peptides, strategies for minimizing side effects, and the importance of muscle preservation. We also get into how peptides can improve sleep, athletic performance, and hormonal balance.

In this episode:

  • How weight loss peptides and hormone optimization can transform wellness and fitness goals.
  • Optimizing peptide regimens to minimize side effects and prevent muscle loss.
  • Why holistic health approaches are crucial for long-term wellness beyond just weight reduction.
  • Why addressing foundational health practices enhances the success of hormonal treatments.
  • How hormone balance plays a crucial role in weight control and muscle preservation, especially during menopause.
  • Why effort and the right mindset are non-negotiables for achieving fitness goals.
  • How the CAROL Bike can aid in maximizing workout efficiency while using peptides.
  • Why women should progress beyond comfort zones in weightlifting for muscle development.
  • How peptides synergize with training, emphasizing workout efficiency for busy individuals.
  • Why long-term peptide use may be necessary for ongoing health maintenance and weight management.
  • How guilt associated with medication for weight control should be reframed as a preventive health measure.
  • How GLP-1 agonists impact the immune system, mental health, and metabolic functions.
  • Tirzepatide’s positive influence on thyroid function.
  • How addressing hormonal imbalances in conjunction with weight loss efforts leads to better outcomes.
  • Why community support can be transformative in the health and fitness journey.

 

Sponsors

Coupon KM20 to get 20% off your order of Vitali Skin Care!

Get 40% off your Cozy Earth Bed Sheet with coupon code HORMONES

 

 

Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.

 

Visit karenmartel.com to explore our comprehensive programs:

  • Bioidentical Hormone Replacement Therapy
  • Individualized Weight Loss Programs 
  • Peptide Therapy for weight loss 

 

Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.

 

Join our Women’s Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!

 

To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.

 

Your host:

Karen Martel

Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert

 

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