229. The New GLP-1 Pill That Could Replace Injections
Release Date: 10/16/2025
253. How Strength Training Can Help You Live to 100 in Good Health
The Kris Gethin Podcast
Aging is usually framed as a genetics problem, a hormone problem, or something medicine will handle later. But the real issue is that most people are not dying because the clock ran out. They are losing strength, muscle, and physical reserve year by year until one illness, one fall, or one short stretch of inactivity exposes how little capacity they have left. In this episode of the Kris Gethin Podcast, I break down why muscle may be the most overlooked form of protection you have against aging, what strength is actually telling you about your future, and why the difference between staying...
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252. The Truth About Caffeine and Energy Drinks Nobody in the Fitness Industry Wants to Admit
The Kris Gethin Podcast
Caffeine is so normal in training culture that nobody questions it anymore. But the shock is this: the same stimulant you’re using to “perform” can be cutting blood flow, drying you out, wrecking sleep quality, and pushing cortisol up while you chase a better physique. If you’re living on pre-workout and energy drinks, you might not be training with energy at all. You’re training with stimulation, and the bill shows up later in recovery, muscle fullness, insulin sensitivity, and long-term performance. In this episode of the Kris Gethin Podcast, I dismantled the science behind why...
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251. Intra-Workout Carbohydrates: What Elite Athletes Know That Influencers Are Getting Wrong
The Kris Gethin Podcast
Most people training for performance, muscle, or body composition have been told that carbohydrates during training are unnecessary, counterproductive for fat loss, or only relevant for endurance athletes. But walk into the hotel rooms of the professional bodybuilders, UFC fighters, and motocross racers at the Arnold Classic and every single one of them is consuming carbohydrates mid-session, because when you understand how glycogen actually fuels high intensity output, the debate stops being a debate. In this episode of the Kris Gethin Podcast, I break down the exact physiology behind why...
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250. The 12-Week At-Home Video Trainer & Why Your Gym Might Be the Reason You're Not Consistent
The Kris Gethin Podcast
How many times have you told yourself, "This week I'm going to be consistent," then two weeks later you're back at day one, annoyed at yourself like you are the problem? The truth is, most people do not fail because they lack discipline. They fail because the system they are using is working against them. The commute, the crowds, the gym hours, the intimidation, the waiting for equipment. Every one of those is a compounding friction point that quietly drains your compliance until skipping becomes easier than showing up. In this episode of the Kris Gethin Podcast, I lay out the exact framework...
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249. Fat Loss Is a Nervous System Decision, Not a Calorie Equation
The Kris Gethin Podcast
Fat loss does not fail because of weak discipline. It fails because the body does not feel safe enough to release stored energy. Long before macros, cardio, or meal timing matter, the nervous system decides whether energy will be mobilized or defended. When sympathetic tone dominates through late nights, artificial light exposure, chronic stress, stimulant reliance, and inflammatory inputs, the body shifts into conservation mode. Cortisol rhythm flattens, insulin sensitivity declines, thyroid conversion slows, leptin signaling weakens, and fat storage becomes protective rather than...
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248. The Recovery Mistake That Creates Chronic Pain
The Kris Gethin Podcast
Injuries rarely fail to heal because the body is incapable. They fail because the healing sequence is interrupted. I see this constantly. People rest, the pain reduces, they feel better, and they assume the tissue has repaired. Then they return to training and it flares again. Healing does not happen through the absence of stress. It happens through the correct sequencing of inflammation, energy production, vascular integrity, and mechanical load. In this episode, I break down the real biology of recovery. I explain why blood flow and mitochondrial output are foundational, how peptides like...
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247. Why Fat Loss Stalls When Sleep Is Off
The Kris Gethin Podcast
Sleep is the most overlooked variable I see in people who train hard, eat well, and still feel stuck. Clients come to me wanting better programs, better supplements, better plans, but when sleep is short or broken, the body simply does not cooperate. It shifts into a defensive state, holds onto fat, and makes progress feel harder than it needs to be. In this episode, I explain why sleep is the strongest predictor of fat loss, muscle retention, and long-term health. I walk through how poor sleep disrupts cortisol rhythm, worsens insulin sensitivity, blunts growth hormone release, and quietly...
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246. Scotty Nelson: Why Stem Cells “Don’t Work” for Most People
The Kris Gethin Podcast
Stem cells and regenerative medicine get talked about like they’re magic. Fix the joint, fix the injury, get back to training. That mindset is exactly why so many people walk away disappointed or saying the treatment didn’t work. I wanted to have a real conversation about what actually determines results once the procedure is over. In this episode, I’m sitting down with Scotty Nelson at CPI in Tijuana to talk about what most people misunderstand about recovery and timing after stem cell treatments. We get into why doing more too soon can work against you, why some people feel changes...
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245. Why I'm Giving Up Bodybuilding
The Kris Gethin Podcast
After decades of training hard, competing, coaching, and living inside a high-intensity routine, you start to understand that discipline evolves. There comes a point where doing more is no longer the smartest decision, even when you are fully capable of it. In this episode, I explain why I am temporarily stepping away from resistance training as part of a structured stem cell recovery protocol, and why following that protocol matters more than ego, habit, or momentum. I talk about restraint as a form of discipline, how recovery phases challenge identity, and why so many driven people struggle...
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244. 8 Nutrition Mistakes Sabotaging Your Performance
The Kris Gethin Podcast
After years of bodybuilding, coaching, and pushing my body to extremes, you start to see patterns you can’t unsee. People chase fat loss harder and harder, slash calories, live on stimulants, and follow rigid nutrition rules that promise control and discipline. It works for a while. Then energy drops. Recovery slows. Hormones take a hit. Inflammation creeps up. And the cycle starts all over again. In this episode, I break down eight nutrition mistakes I see repeatedly sabotaging health and long-term progress. We talk about extreme calorie deficits, processed protein overload, missing...
info_outlineGLP-1s have dominated the headlines, but the next wave of compounds is already here, and they’re changing the conversation on fat loss, performance, and longevity. In this episode, I break down the science behind four emerging therapies and why you need to know about them now.
We cover how Afoglipron, the first oral non-peptide GLP-1, removes the barrier of injections while delivering results on par with semaglutide. You’ll hear why Teriparatide, originally used for osteoporosis, may reduce visceral fat and protect bone density at the same time. I also dive into Mazdutide, a dual GLP-1/glucagon agonist that suppresses appetite while boosting energy expenditure, and Tesofensine, a brain-targeting appetite suppressant with powerful effects on cravings.
I share what the latest clinical data shows, the benefits and risks for both general populations and athletes, and how these compounds could fit into the bigger picture of training, nutrition, and longevity.
This is a must-listen.
What's Discussed:
00:05 — Why GLP-1s have exploded and what’s next beyond semaglutide
01:53 — Afoglipron: The first oral GLP-1 and why it’s a game changer
07:16 — Teriparatide: Surprising fat loss potential in a bone health drug
10:29 — Mazdutide: The “eat less, burn more” dual agonist
13:17 — Tesofensine: Targeting food noise and cravings in the brain
16:20 — Are these drugs the future of fat loss, or a Pandora’s box?
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Find more from Kris:
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