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Philosophers on psychedelics

Many Minds

Release Date: 05/14/2025

In search of names show art In search of names

Many Minds

Alright, friends—we’ve come to the end of the 2025 run of Many Minds! Our final episode of the year is an audio essay by yours truly. This is a classic format for the show, one that we only do every so often. Today’s essay is about names. It’s about the question of whether animals have something like names for each other. And it’s also about a deeper question: What even is a name? How do humans use names? How does the historical and ethnographic record kind of complicate our everyday understanding of what names are. I had a lot of fun putting this together, and I do hope you...

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The value of animal cultures show art The value of animal cultures

Many Minds

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What is memory for? show art What is memory for?

Many Minds

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Many Minds

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Monsters and their makers show art Monsters and their makers

Many Minds

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The age of social AI show art The age of social AI

Many Minds

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Many Minds

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Many Minds

One afternoon you decide to snub your responsibilities and go for a hike. You spend a few hours in the woods or the mountains. You study the bark of trees, you bathe in birdsong, you let your eyes roam along a distant ridgeline. And you come back feeling better, restored somehow—like you have more energy, more patience, more bandwidth. We've all, I'm guessing, had experiences like this. But what's behind these effects? Why would nature restore us? What's the evidence that it really does? And what is even being restored, actually? My guest today is . Marc is an Associate Professor in the...

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From the archive: Revisiting the dawn of human cognition show art From the archive: Revisiting the dawn of human cognition

Many Minds

Hi friends! We're taking a much-needed summer pause—we'll have new episodes for you later in September. In the meanwhile, enjoy this pick from our archives! ------- [originally aired June 1, 2023] There's a common story about the human past that goes something like this. For a few hundred thousand years during the Stone Age we were kind of limping along as a species, in a bit of a cognitive rut, let’s say. But then, quite suddenly, around 30 or 40 thousand years ago in Europe, we really started to come into our own. All of a sudden we became masters of art and ornament, of symbolism and...

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From the archive: Of molecules and memories show art From the archive: Of molecules and memories

Many Minds

Hi friends! We're taking a much-needed August pause—we'll have new episodes for you in September. In the meanwhile, enjoy this pick from our archives! _____ [originally aired February 8, 2024] Where do memories live in the brain? If you've ever taken a neuroscience class, you probably learned that they're stored in our synapses, in the connections between our neurons. The basic idea is that, whenever we have an experience, the neurons involved fire together in time, and the synaptic connections between them get stronger. In this way, our memories for those experiences become minutely etched...

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More Episodes

Some call it the "psychedelic renaissance." In the last decade or so, interest in psychedelic drugs has surged—and not just among Silicon Valley types and psychiatrists and neuroscientists. It's also surged among a stereotypically soberer crowd: academic philosophers. The reasons are clear. With their varied and sometimes transformative effects, psychedelics raise ethical questions, epistemological questions, metaphysical questions, questions about the nature of experience and the nature of the mind.

My guest today is Dr. Chris Letheby. Chris is a philosopher of cognitive science at the University of Western Australia and the author of the 2021 book, Philosophy of Psychedelics.

Here, Chris and I talk about the so-called classic psychedelics—LSD, psilocybin, ayahuasca, and others—and how interest in them has gone through three distinct waves. We discuss the effects that these substances seem to have, in particular their capacity to treat certain psychiatric conditions and their tendency to induce "mystical-like" experiences. We consider the idea that psychedelics might serve as agents of moral enhancement. And we dig into the psychological and neural mechanisms by which psychedelics seem to have their diverse—and often salutary—effects. Along the way, we talk about ontological shock, comforting delusions, brain plasticity, unselfing, microdosing, placebo effects and adverse effects, physicalism and idealism, the REBUS model, environmental virtues, plant consciousness, meditation, and much more.

Maybe this is obvious but this episode is not just for the seasoned psychonauts out there. Whatever your personal experience with these substances, they offer a distinctive window into the mind—a new way of grappling with big questions. Perhaps this much is also obvious but we're not encouraging or endorsing the use of psychedelics here—just offering a little fuel for your intellectual fires!

Alright friends, on to my conversation w/ Dr. Chris Letheby. Enjoy!

 

A transcript of this episode is available here

 

Notes and links

4:00 – For a brief historical overview of research into psychedelics, see this paper.

8:30 – For work by an early trailblazer in the philosophy of psychedelics, see Thomas Metzinger’s Being No One.

12:30 – For our earlier episode on the psychology and philosophy of visual illusions, see here. 

18:00 – For a history of the concept of “set and setting,” see here.

19:00 – A 2024 review of “adverse events” in classic psychedelics.

26:00 – A blog post on the history of the term “psychedelic.”

27:00 – A recent review and meta-analysis of the use of psychedelic therapy for depressive symptoms.

31:00 – On mystical experience see Walter Stace’s classic work, Mysticism and Philosophy. On the measurement of mystical-type experiences, see, e.g., Walter Pahnke’s paper here.

36:00 – On the idea of “psychoplastogens,” see here.

39:00 – See our earlier audio essay on placebo effects.

41:00 – For the study using Ritalin as an active placebo, see here. 

44:00 – Michael Pollan’s book on psychedelics is here.

48:00 – On the idea of “idealism,” see here.

50:30 – For the 2021 study on psychedelics’ capacity to alter metaphysical beliefs, see here.

54:00 – For Dr. Letheby and collaborators’ paper about the “mysticism wars,” see here.

1:02:00 – For a popular article on the possibility that psychedelics reduce fear of death, see here.

1:03:00 – For Dr. Letheby’s paper on psychedelics and the fear of death, see here.

1:11:00 – The phrase “comforting delusion” comes from an article by Michael Pollan.

1:15:00 – For the “REBUS model,” see here.

1:20:00 – On the idea that psychedelics could serve as agents of moral enhancement, see the paper by Brian Earp here.

1:21:00 – For Dr. Letheby’s paper on psychedelics and environmental virtues, see here. For his paper on psychedelics and forgiveness, see here.

1:23:00 – On the subfield of “virtue ethics,” see here. On the virtue of “living in place,” see the paper by Nin Kirkham here.

1:28:00 – For the New Yorker article, by Matthew Hutson, on how psychedelics led him to see trees as smart, see here. For the study, led by Sandeep Nayak, on psychedelics leading people to expand their attributions of consciousness, see here.

1:32:00 – For a first paper by Dr. Letheby on the comparison between meditation and psychedelics, see here.

 

Recommendations

Psychedelic Experience, Aidan Lyon

Varieties of Psychedelic Experience, Robert Masters & Jean Houston

The Antipodes of the Mind, Benny Shanon

 

Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala.

 

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