Dr. Barry Popkin on MAHA and Ultra-Processed Foods
Death Clock
On this week’s episode, Brent is joined by Dr. Barry Popkin, a leading nutrition researcher known for his work on ultra-processed foods and global diet trends. Dr. Popkin explains how modern food systems have reshaped what we eat, why ultra-processed foods are linked to obesity, diabetes, and heart disease, and how liquid calories and added sugars uniquely drive metabolic harm. The conversation also examines the political and industry forces that shape food policy in the U.S., including regulation, lobbying, and why meaningful dietary reform has been so difficult to implement. Hope you...
info_outline
Dr. Emily Lantz on Protein
Death Clock
Today, Brent sits down with Dr. Emily Lantz, a leading researcher in nutrition and muscle health, to unpack one of the most talked-about topics in longevity: protein. She explains how much protein we actually need, why timing and quality matter just as much as quantity, and how protein intake changes as we age. She offers insights on animal versus plant sources, supplements, fasting, strength training and so much more. It's a can't miss episode. Hope you enjoy.
info_outline
Dr. Anne Cappola on Thyroid Health
Death Clock
In this episode, Brent speaks with Dr. Anne Cappola, a leading endocrinologist at the University of Pennsylvania, about thyroid health. Using both clinical insight and Brent’s personal experience as a parent, they break down what the thyroid does, how hypo- and hyperthyroidism show up in real life, how these conditions are diagnosed, and what treatment actually looks like. The discussion covers common symptoms, when testing matters, why TSH is the key marker, and how thyroid health fits into aging, longevity, and everyday wellbeing. Hope you enjoy.
info_outline
Dr. Luke Laffin on Hypertension
Death Clock
This week, Brent sits down with Dr. Luke Laffin, a preventive cardiologist and hypertension specialist, to break down what blood pressure really tells us about long-term health. Dr. Laffin explains why high blood pressure is one of the strongest predictors of heart attack, stroke, kidney disease, and dementia, even when it shows up early or seems “borderline.” They discuss how blood pressure should be measured correctly, the difference between office readings and home monitoring, and why lifestyle changes alone aren’t always enough. The conversation also covers when medication makes...
info_outline
Dr. Todd Dorfman on Brent’s Latest Heart Procedure
Death Clock
This week, Brent speaks with his personal physician, Dr. Todd Dorfman, for an update on his own health journey. Using Brent as a real-world case study, they walk through the discovery of an anomalous coronary artery, the risks and benefits of advanced cardiac diagnostics, and why more testing isn’t always better. The conversation then shifts to prevention. Dr. Dorfman shares how he thinks about cholesterol, ApoB, Alzheimer’s risk, statins, PCSK9 inhibitors, GLP-1 drugs, and other emerging therapies when you don’t have disease but want to stay ahead of it. As always, Dr. Dorfman is a...
info_outline
Dr. John Norcross on New Year’s Resolutions
Death Clock
Happy New Year! We’re releasing this week’s episode a day early to help you stay on top of your New Year’s Resolutions. Our guest this week is Dr. John Norcross, a clinical psychologist and longtime researcher of behavior change. Drawing on decades of research, Dr. Norcross breaks down the science of goal setting, from choosing realistic resolutions to building action plans, accountability, and tracking progress. They discuss why slips are normal, how rewards and consequences actually motivate behavior, and why preparation matters just as much as action. It’s a strong guide to making...
info_outline
Best of 2025
Death Clock
To close out 2025, Brent revisits some of the most impactful conversations of the year, highlighting ideas that challenge how we think about health, aging, and prevention. The clips touch on longevity hot spots, heart disease risk, cancer, metabolic health, fitness, supplements, and more. Thank you for a great 2025. We can’t wait to bring you more episodes and insights in the new year. Hope you enjoy.
info_outline
Dr. Seth Gillihan on Cognitive Behavioral Therapy
Death Clock
This week, clinical psychologist and CBT expert Dr. Seth Gillihan returns to the show for a third time to have a conversation about how our thoughts, behaviors, and physical health are deeply intertwined. Drawing on examples from everyday life, Dr. Gillihan explains how cognitive behavioral therapy helps people build a healthier relationship with their thoughts and make real, sustainable behavior change. The episode explores when therapy is most useful, when fundamental habits like sleep and exercise may matter more, and how CBT tools can bridge the gap between knowing what’s good for us and...
info_outline
Dr. Ziyad Al-Aly on Long COVID
Death Clock
This week, Brent is joined by Dr. Ziyad Al-Aly, a physician-researcher known for some of the most comprehensive work on long COVID and its long-term impact on the body. Dr. Al-Aly explains what the latest data shows about lingering symptoms, who’s most at risk, and how COVID increases the chances of conditions like heart disease, diabetes, and cognitive decline long after infection. They discuss what we now understand about reinfections, vaccines, viral persistence, and the mechanisms driving long COVID, along with the practical steps people can take to lower risk and protect their long-term...
info_outline
The Mission of Death Clock
Death Clock
In this solo episode, Brent takes a step back and explores the mission of Death Clock, reflecting on the journey of the company thus far. He then pulls together the biggest lessons from prior episodes and lays out the core principles experts agree matter most for living longer and staying healthy. He walks through the fundamentals and explains how science has changed his own approach to day-to-day health. It’s a straightforward, practical recap of what actually makes a difference and the steps anyone can start taking now. Hope you enjoy.
info_outlineIn this episode of Death Clock, Brent talks with Dr. Thomas Seyfried, an impassioned biologist and leading voice in the metabolic theory of cancer. Seyfried argues that the origins of cancer lie not in mutations, but in dysfunctional mitochondria, and that treating cancer as a metabolic disease opens the door to radically different therapies. They explore the promise and pitfalls of ketogenic diets, fasting, and metabolic interventions, and challenge conventional thinking on everything from chemo to cancer screening. Hope you enjoy.