E271 - A Look Back at This Year in Psychopharmacology with Dr. Roger McIntyre
Release Date: 12/17/2025
E290 - ADHD and Substance Use Disorders: Treatment Challenges with Dr. Timothy Wilens
NEI Podcast
In this episode, Dr. Andy Cutler speaks with Dr. Tim Wilens about the complex relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders. They discuss how to distinguish ADHD from substance-related cognitive symptoms, determine when co-occurring conditions should be treated concurrently, and select appropriate ADHD medications based on the substance involved. Dr. Wilens also examines stimulant misuse and diversion, the role of nonstimulants, what is known about centanafadine’s abuse potential, and practical approaches to monitoring treatment without...
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E289 - Recognizing and Managing the Biggest Mistakes in Psychopharmacology with Dr. Thomas Schwartz
NEI Podcast
Originally released in 2021, this episode features Dr. Thomas Schwartz discussing common mistakes in psychopharmacology and how psychiatric clinicians can recognize and manage them. He explores diagnostic uncertainty, medication dosing, informed consent and monitoring, and rational versus irrational polypharmacy. He also considers how clinicians can reassess inherited diagnoses, learn from prescribing errors, and preserve the therapeutic relationship when mistakes occur. Thomas L. Schwartz, MD, is a Distinguished Teaching Professor at Norton College of Medicine, SUNY Upstate...
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E288 - PsychopharmaPearls: Kratom—What Clinicians Need to Know with Dr. William Sauvé
NEI Podcast
In this episode of PsychopharmaPearls, Dr. Andy Cutler and Dr. Will Sauvé discuss what clinicians need to know about kratom. They review why patients use it, signs of misuse, dependence, or withdrawal, and key pharmacologic and safety concerns. The conversation also offers practical guidance for discussing kratom use and incorporating it into treatment planning. William Sauvé, MD, is a board-certified psychiatrist and Chief Medical Officer at Osmind. He has extensive experience in interventional psychiatry, including TMS and esketamine, and previously served for 11 years as an...
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E287 - Deprescribing Practices in Psychiatry with Drs. Stephen Stahl and Jeffrey Strawn
NEI Podcast
In this episode, Dr. Andy Cutler is joined by Drs. Stephen Stahl and Jeffrey Strawn to discuss deprescribing practices in psychiatry. They explore why deprescribing is an essential clinical skill, how to determine whether a patient still needs a medication, dose, or combination, and how to approach tapering in a way that balances relapse prevention, withdrawal risk, and patient-centered care. The conversation also covers practical considerations for deprescribing antidepressants, antipsychotics, benzodiazepines, and sedative-hypnotics, with attention to common pitfalls and strategies for...
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E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre
NEI Podcast
In this episode, Dr. Andy Cutler is joined by Dr. Roger McIntyre to discuss GLP-1 receptor agonists in psychiatry and why these medications may be relevant beyond weight loss. They explore the emerging role of GLP-1s in metabolic psychiatry, including potential connections with mood disorders, cognition, reward pathways, cardiometabolic health, and psychiatric medication-associated weight gain. Dr. McIntyre also discusses what psychiatric providers should know now, where the evidence is still evolving, and what future research is needed before GLP-1 or incretin-based therapies could be...
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E285 - Re-release: Eating Disorders, Nutrition, and the Brain with Dr. Cynthia Bulik
NEI Podcast
Originally released in June 2023, this episode features Dr. Cynthia Bulik in a discussion of eating disorders, nutrition, and the brain. The conversation explores anorexia nervosa, bulimia nervosa, binge eating disorder, ARFID, common misconceptions about eating disorders, and the evolving understanding of how biology, genetics, and environment shape risk, diagnosis, and recovery. Cynthia Bulik, PhD, FAED, is a Distinguished Professor of Eating Disorders in the Department of Psychiatry at the University of North Carolina at Chapel Hill and Professor of Nutrition in the...
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E284 - Nutritional Interventions in Psychiatry: Hype vs. Evidence with Dr. Bhagwan Bahroo
NEI Podcast
In this episode, Dr. Andy Cutler talks with Dr. Bhagwan Bahroo about nutritional interventions in psychiatry, including diet, supplements, metabolic health, inflammation, and the gut-brain axis. They explore where the evidence is strongest, where hype outpaces the data, and how clinicians can discuss nutritional strategies as adjunctive tools without losing focus on core treatments. Bhagwan A. Bahroo, MD, DLFAPA, is a board-certified psychiatrist in adult, addiction, and forensic psychiatry and an Assistant Professor at the Uniformed Services University of the Health...
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E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome
NEI Podcast
In this episode of PsychopharmaPearls, Dr. Andy Cutler talks with Dr. Leslie Citrome about akathisia, a common but often misdiagnosed antipsychotic side effect that can look like agitation, anxiety, irritability, or worsening psychiatric symptoms. They discuss how to recognize akathisia in clinical practice, distinguish it from true agitation, identify key timing and symptom clues, and avoid common treatment...
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E282 - 2026 NEI Spring Congress Extended Q&A: Anxiety, Schizophrenia, and Postpartum Mood Disorders with Drs. Strawn, Correll, and Payne
NEI Podcast
This episode features extended Q&A sessions addressing unanswered audience questions from select presentations delivered at the 2026 NEI Spring Congress in Kissimmee, Florida: (00:53) From Avoidance to Action: Evidence-based Pathways to Recovery for Difficult-to-Treat Anxiety by (15:21) Perhaps the Grass Is Greener: Why, When, and How to Switch or Combine Treatments for Schizophrenia by (34:42) The Other Side of Motherhood: Advances in the Treatment of Postpartum Mood and Anxiety Disorders by ...
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E281 - ADHD, Hormones, or Aging? Sorting Out Cognitive Complaints in Women with Dr. Neill Epperson
NEI Podcast
In this episode, Dr. Andy Cutler speaks with Dr. Neill Epperson about how to evaluate cognitive complaints in women. They discuss how to differentiate between ADHD, hormonal changes (such as perimenopause), mood and anxiety disorders, and age-related cognitive decline. The conversation highlights key clinical clues, including symptom timing and fluctuation, to improve diagnostic accuracy. Practical strategies for assessment and treatment are reviewed to help clinicians make more informed, individualized decisions. C. Neill Epperson, MD, is the Robert Freedman Endowed Professor...
info_outlineJoin Drs. Andy Cutler and Roger McIntyre as they discuss the most significant advancements in psychopharmacology over the past year. Their conversation highlights groundbreaking developments and innovations in the field of psychiatry.
Roger McIntyre, MD, FRCPC, is a globally recognized psychiatrist and psychopharmacologist who holds pivotal roles in academia, research, and leadership. His research primarily focuses on the phenomenology, neurobiology, and development of novel therapeutics for mood disorders. Dr. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto.
Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York.
Resources
Thanarajah ES et al. Soft drink consumption and depression mediated by gut microbiome alterations. JAMA Psychiatry 2025;82(11):1095–1102. doi:10.1001/jamapsychiatry.2025.2579
Durgam S et al. Lumateperone as adjunctive therapy in patients with major depressive disorder: results from a randomized, double-blind, phase 3 trial. J Clin Psychiatry 2025;86(4):25m15848. doi: 10.4088/JCP.25m15848
Hendershot CS et al. Once-weekly semaglutide in adults with alcohol use disorder: a randomized clinical trial. JAMA Psychiatry 2025;82(4):395–405. doi: 10.1001/jamapsychiatry.2024.4789
Aron L et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 2025;645:712–21. doi: 10.1038/s41586-025-09335-x
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