NEI Podcast
The Neuroscience Education Institute (NEI) is committed to help raise the standard of mental health by providing imaginative medical education that focuses on the highest level of learning. Each episode offers an opportunity to learn about current issues in psychiatry from key opinion leaders in the medical field. NEI's Podcast would be of value to anyone with an interest in mental health, neuropsychiatric diseases, and psychopharmacology. Accreditation: NEI is accredited with commendation by the ACCME to provide continuing medical education for physicians.
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E290 - ADHD and Substance Use Disorders: Treatment Challenges with Dr. Timothy Wilens
09/09/2026
E290 - ADHD and Substance Use Disorders: Treatment Challenges with Dr. Timothy Wilens
In this episode, Dr. Andy Cutler speaks with Dr. Tim Wilens about the complex relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders. They discuss how to distinguish ADHD from substance-related cognitive symptoms, determine when co-occurring conditions should be treated concurrently, and select appropriate ADHD medications based on the substance involved. Dr. Wilens also examines stimulant misuse and diversion, the role of nonstimulants, what is known about centanafadine’s abuse potential, and practical approaches to monitoring treatment without undermining the therapeutic relationship. Timothy E. Wilens, MD, is chief of the Division of Child and Adolescent Psychiatry and is co-director of the Center for Addiction Medicine at Massachusetts General Hospital. He is the MGH Trustees Chair in Addiction Medicine and a professor of psychiatry at Harvard Medical School. Dr. Wilens’ research interests include the relationship among ADHD, bipolar disorder, and substance use disorders, embedded health care models, and the pharmacotherapy of ADHD across the lifespan. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E289 - Recognizing and Managing the Biggest Mistakes in Psychopharmacology with Dr. Thomas Schwartz
08/26/2026
E289 - Recognizing and Managing the Biggest Mistakes in Psychopharmacology with Dr. Thomas Schwartz
Originally released in 2021, this episode features Dr. Thomas Schwartz discussing common mistakes in psychopharmacology and how psychiatric clinicians can recognize and manage them. He explores diagnostic uncertainty, medication dosing, informed consent and monitoring, and rational versus irrational polypharmacy. He also considers how clinicians can reassess inherited diagnoses, learn from prescribing errors, and preserve the therapeutic relationship when mistakes occur. Thomas L. Schwartz, MD, is a Distinguished Teaching Professor at Norton College of Medicine, SUNY Upstate Medical University in Syracuse, New York. He is an award-winning educator deeply involved in medical student and resident training, as well as the development of continuing medical education in psychiatry. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E288 - PsychopharmaPearls: Kratom—What Clinicians Need to Know with Dr. William Sauvé
08/12/2026
E288 - PsychopharmaPearls: Kratom—What Clinicians Need to Know with Dr. William Sauvé
In this episode of PsychopharmaPearls, Dr. Andy Cutler and Dr. Will Sauvé discuss what clinicians need to know about kratom. They review why patients use it, signs of misuse, dependence, or withdrawal, and key pharmacologic and safety concerns. The conversation also offers practical guidance for discussing kratom use and incorporating it into treatment planning. William Sauvé, MD, is a board-certified psychiatrist and Chief Medical Officer at Osmind. He has extensive experience in interventional psychiatry, including TMS and esketamine, and previously served for 11 years as an active-duty Navy psychiatrist. He also serves on the faculty of the Neuroscience Education Institute. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: X: Instagram: Facebook: LinkedIn:
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E287 - Deprescribing Practices in Psychiatry with Drs. Stephen Stahl and Jeffrey Strawn
07/29/2026
E287 - Deprescribing Practices in Psychiatry with Drs. Stephen Stahl and Jeffrey Strawn
In this episode, Dr. Andy Cutler is joined by Drs. Stephen Stahl and Jeffrey Strawn to discuss deprescribing practices in psychiatry. They explore why deprescribing is an essential clinical skill, how to determine whether a patient still needs a medication, dose, or combination, and how to approach tapering in a way that balances relapse prevention, withdrawal risk, and patient-centered care. The conversation also covers practical considerations for deprescribing antidepressants, antipsychotics, benzodiazepines, and sedative-hypnotics, with attention to common pitfalls and strategies for safer, more intentional medication management. Stephen M. Stahl, MD, PhD, DSc (Hon.), is a psychiatrist, psychopharmacologist, and internationally recognized educator in clinical neuroscience and psychopharmacology. He is the author of widely used educational resources including Stahl’s Essential Psychopharmacology, Stahl’s Prescriber’s Guide, and Stahl’s Deprescriber’s Guide, and his work focuses on translating complex neurobiology into practical clinical concepts for mental health clinicians. Jeffrey R. Strawn, MD, FAACAP, is a Professor of Psychiatry, Pediatrics, and Clinical & Translational Pharmacology at the University of Cincinnati, Ohio. He is Director of the UC Anxiety Disorders Research Program and Associate Vice Chair of Research in the Department of Psychiatry & Behavioral Neuroscience at UC, and he is the author of Stahl’s Deprescriber’s Guide. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Strawn, JR, Stahl SM. Stahl’s Deprescriber’s Guide. Cambridge University Press; 2026. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre
07/15/2026
E286 - GLP-1 Agonists in Psychiatry: Beyond Weight Loss with Dr. Roger McIntyre
In this episode, Dr. Andy Cutler is joined by Dr. Roger McIntyre to discuss GLP-1 receptor agonists in psychiatry and why these medications may be relevant beyond weight loss. They explore the emerging role of GLP-1s in metabolic psychiatry, including potential connections with mood disorders, cognition, reward pathways, cardiometabolic health, and psychiatric medication-associated weight gain. Dr. McIntyre also discusses what psychiatric providers should know now, where the evidence is still evolving, and what future research is needed before GLP-1 or incretin-based therapies could be considered part of psychiatric treatment. Roger S. McIntyre, MD, FRCPC, is Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network in Toronto. He is an internationally recognized expert in mood disorders and psychopharmacology, with published scholarship and presentations exploring the relevance of GLP-1 receptor agonists to psychiatry. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E285 - Re-release: Eating Disorders, Nutrition, and the Brain with Dr. Cynthia Bulik
07/01/2026
E285 - Re-release: Eating Disorders, Nutrition, and the Brain with Dr. Cynthia Bulik
Originally released in June 2023, this episode features Dr. Cynthia Bulik in a discussion of eating disorders, nutrition, and the brain. The conversation explores anorexia nervosa, bulimia nervosa, binge eating disorder, ARFID, common misconceptions about eating disorders, and the evolving understanding of how biology, genetics, and environment shape risk, diagnosis, and recovery. Cynthia Bulik, PhD, FAED, is a Distinguished Professor of Eating Disorders in the Department of Psychiatry at the University of North Carolina at Chapel Hill and Professor of Nutrition in the Gillings School of Global Public Health. She is the founding director of the UNC Center of Excellence for Eating Disorders and directs the Centre for Eating Disorders Innovation at Karolinska Institutet, with research focused on the biology, genetics, prevention, and treatment of eating disorders. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E284 - Nutritional Interventions in Psychiatry: Hype vs. Evidence with Dr. Bhagwan Bahroo
06/17/2026
E284 - Nutritional Interventions in Psychiatry: Hype vs. Evidence with Dr. Bhagwan Bahroo
In this episode, Dr. Andy Cutler talks with Dr. Bhagwan Bahroo about nutritional interventions in psychiatry, including diet, supplements, metabolic health, inflammation, and the gut-brain axis. They explore where the evidence is strongest, where hype outpaces the data, and how clinicians can discuss nutritional strategies as adjunctive tools without losing focus on core treatments. Bhagwan A. Bahroo, MD, DLFAPA, is a board-certified psychiatrist in adult, addiction, and forensic psychiatry and an Assistant Professor at the Uniformed Services University of the Health Sciences in Bethesda, Maryland. He has extensive clinical experience at Walter Reed National Military Medical Center and has worked in interventional psychiatry, including TMS and esketamine, with an interest in nutrition and its role in mental health. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome
06/03/2026
E283 - PsychopharmaPearls: When Akathisia Looks Like Agitation with Dr. Leslie Citrome
In this episode of PsychopharmaPearls, Dr. Andy Cutler talks with Dr. Leslie Citrome about akathisia, a common but often misdiagnosed antipsychotic side effect that can look like agitation, anxiety, irritability, or worsening psychiatric symptoms. They discuss how to recognize akathisia in clinical practice, distinguish it from true agitation, identify key timing and symptom clues, and avoid common treatment mistakes, including why benztropine is not an appropriate treatment for akathisia. Leslie Citrome, MD, MPH, is Clinical Professor of Psychiatry and Behavioral Sciences at New York Medical College and an internationally recognized expert in psychopharmacology and clinical trial interpretation. He has authored more than 600 scientific publications and frequently lectures on applying research findings to real-world psychiatric practice. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E282 - 2026 NEI Spring Congress Extended Q&A: Anxiety, Schizophrenia, and Postpartum Mood Disorders with Drs. Strawn, Correll, and Payne
05/20/2026
E282 - 2026 NEI Spring Congress Extended Q&A: Anxiety, Schizophrenia, and Postpartum Mood Disorders with Drs. Strawn, Correll, and Payne
This episode features extended Q&A sessions addressing unanswered audience questions from select presentations delivered at the 2026 NEI Spring Congress in Kissimmee, Florida: (00:53) From Avoidance to Action: Evidence-based Pathways to Recovery for Difficult-to-Treat Anxiety by (15:21) Perhaps the Grass Is Greener: Why, When, and How to Switch or Combine Treatments for Schizophrenia by (34:42) The Other Side of Motherhood: Advances in the Treatment of Postpartum Mood and Anxiety Disorders by Fall Congress Get $100 off NEI Fall Congress registration with code POD26. Go to to sign up today! Membership As a valued NEI Podcast listener, Dr. Cutler's offering you 20% off new NEI Membership with code CUTLER20. Go to and join now! Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E281 - ADHD, Hormones, or Aging? Sorting Out Cognitive Complaints in Women with Dr. Neill Epperson
05/06/2026
E281 - ADHD, Hormones, or Aging? Sorting Out Cognitive Complaints in Women with Dr. Neill Epperson
In this episode, Dr. Andy Cutler speaks with Dr. Neill Epperson about how to evaluate cognitive complaints in women. They discuss how to differentiate between ADHD, hormonal changes (such as perimenopause), mood and anxiety disorders, and age-related cognitive decline. The conversation highlights key clinical clues, including symptom timing and fluctuation, to improve diagnostic accuracy. Practical strategies for assessment and treatment are reviewed to help clinicians make more informed, individualized decisions. C. Neill Epperson, MD, is the Robert Freedman Endowed Professor and Chair of the Department of Psychiatry at the CU Anschutz School of Medicine. She is an internationally recognized expert in women’s mental health, with research focused on the effects of hormonal transitions—such as puberty, pregnancy, and menopause—on mood, cognition, and psychiatric disorders. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E280 - PsychopharmaPearls: Managing Rebound Insomnia with Dr. Thomas Schwartz
04/22/2026
E280 - PsychopharmaPearls: Managing Rebound Insomnia with Dr. Thomas Schwartz
In this episode, Dr. Andy Cutler speaks with Dr. Thomas Schwartz about insomnia related to antidepressant discontinuation, including how rebound and withdrawal symptoms can emerge when tapering or stopping treatment. They review the underlying mechanisms, clinical risk factors, and how to distinguish discontinuation-related insomnia from relapse of depression or primary sleep disorders. The discussion emphasizes practical, evidence-informed strategies for safely tapering antidepressants and managing sleep disturbance in psychiatric practice. Thomas L. Schwartz, MD, is a Distinguished Teaching Professor at Norton College of Medicine, SUNY Upstate Medical University in Syracuse, New York. He is an award-winning educator deeply involved in medical student and resident training, as well as the development of continuing medical education in psychiatry. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E279 - Sleep in Bipolar Disorder: Clinical Insights with Dr. Holly Swartz
04/08/2026
E279 - Sleep in Bipolar Disorder: Clinical Insights with Dr. Holly Swartz
In this episode, Dr. Andy Cutler speaks with Dr. Holly Swartz about the critical role of sleep and circadian rhythms in bipolar disorder, including how sleep disturbance can function as both a symptom and trigger of mood episodes. They discuss how clinicians can better assess sleep to identify early warning signs of relapse, along with practical strategies for intervention, including applying principles of Interpersonal and Social Rhythm Therapy (IPSRT), choosing between behavioral and pharmacologic treatments for insomnia, and avoiding sleep medications that may destabilize mood. The episode offers a clinically focused approach to improving relapse prevention through better sleep management. Holly A. Swartz, MD, is Professor of Psychiatry at the University of Pittsburgh, Director of the Center for Advanced Psychotherapy, and Medical Director of the Depression and Manic Depression Prevention Program. An internationally recognized expert in bipolar disorder treatment, she is President of the International Society for Bipolar Disorders and known for advancing Interpersonal and Social Rhythm Therapy (IPSRT), an evidence-based approach targeting sleep, circadian rhythms, and mood stabilization to prevent relapse. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Interpersonal and Social Rhythm Therapy – Depression and Bipolar Support Alliance – Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at nei.global/spring Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E278 - Re-release: Autism Spectrum Disorder and Comorbidities with Dr. Robyn Thom
03/25/2026
E278 - Re-release: Autism Spectrum Disorder and Comorbidities with Dr. Robyn Thom
In this revisited episode, Dr. Robyn Thom discusses autism spectrum disorder (ASD) and the psychiatric comorbidities that frequently accompany it. She reviews how ASD is diagnosed, the core domains of social communication differences and restricted or repetitive behaviors, and why treatment often focuses on co-occurring conditions such as anxiety, ADHD, sleep disorders, and agitation. Dr. Thom also shares practical strategies for evaluating agitation, distinguishing overlapping symptoms, and selecting behavioral and pharmacologic interventions to support patients with ASD across the lifespan. Robyn Thom, MD, is an Assistant Professor of Psychiatry at Harvard Medical School and a staff psychiatrist at the Massachusetts General Hospital Lurie Center for Autism. She specializes in treating children and adults with autism spectrum disorder and other neurodevelopmental conditions, with clinical and research interests in psychiatric comorbidities, anxiety, and mood disorders. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E277 - Shaping Recovery: Early Psychosis Outcomes and Engagement with Dr. Robert Cotes
03/11/2026
E277 - Shaping Recovery: Early Psychosis Outcomes and Engagement with Dr. Robert Cotes
In this episode, Dr. Andy Cutler talks with Dr. Robert Cotes about optimizing outcomes in early psychosis and why the first episode is a critical window for intervention. They discuss the impact of duration of untreated psychosis, recovery trajectories after a first episode, and what to measure beyond symptom reduction—including functional outcomes, cognition, and relapse risk. The conversation also highlights strategies for engaging young adults and families in coordinated specialty care, early identification of clinical high risk for psychosis, and innovations aimed at improving long-term recovery. Robert O. Cotes, MD, is Professor of Psychiatry and Behavioral Sciences at Emory University School of Medicine and Chief of Psychiatry at Grady Health System in Atlanta. He directs the Clinical and Research Program for Psychosis at Grady, which includes Project ARROW, a coordinated specialty care program for young people with early psychosis, and a specialized clozapine clinic for treatment-resistant schizophrenia. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E276 - PsychopharmaPearls: Choosing Ketamine Treatment with Dr. Lisa Harding
02/25/2026
E276 - PsychopharmaPearls: Choosing Ketamine Treatment with Dr. Lisa Harding
PsychopharmaPearls is NEI’s focused podcast series highlighting the clinical insights that can sharpen your prescribing decisions. In this episode, Dr. Andy Cutler talks with Dr. Lisa Harding about how to choose between IV ketamine and intranasal esketamine for patients with difficult-to-treat depression. They unpack the differences that truly matter in practice—from patient selection and monitoring to access, cost, and common missteps. Tune in for practical pearls you can immediately apply to select the right treatment for the right patient. Lisa Harding, MD is a board-certified psychiatrist and nationally recognized depression specialist with deep expertise in interventional psychiatry. She has performed more than 4,000 procedures, including electroconvulsive therapy (ECT), intravenous ketamine, intranasal esketamine, and transcranial magnetic stimulation (TMS). Dr. Harding is known for her thoughtful approach to complex, treatment-resistant depression, integrating advanced somatic therapies, psychopharmacology, and psychotherapy. She serves as an Assistant Clinical Professor of Psychiatry at Yale University in New Haven, Connecticut. Andrew J. Cutler, MD is a leading psychiatrist, psychopharmacology expert, and clinical researcher with decades of experience in CNS drug development. As Chief Medical Officer of Neuroscience Education Institute and EMA Wellness, he brings frontline clinical insight together with deep knowledge of the evidence base. Dr. Cutler is widely recognized for translating research into practical guidance for everyday practice and serves as a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Sanacora G et al. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry 2017;74(4):399-405. McIntyre RS et al. Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation. Am J Psychiatry 2021;178(5):383-399. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E275 - Busting Myths About ADHD Medications with Dr. Tim Wilens
02/11/2026
E275 - Busting Myths About ADHD Medications with Dr. Tim Wilens
In this episode, Dr. Andy Cutler talks with Dr. Tim Wilens about enduring myths surrounding ADHD diagnosis and treatment, beginning with why misconceptions about overdiagnosis and misuse continue to shape clinical hesitation. They explore common misunderstandings about ADHD medications—including stimulants versus non-stimulants, concerns about diversion, personality changes, and long-term safety—and contrast stigma-driven narratives with the clinical evidence. The conversation equips clinicians with practical, evidence-based strategies to address patient fears, counter misinformation, and make thoughtful, individualized treatment decisions. Timothy Wilens, MD, is chief of the Division of Child and Adolescent Psychiatry and is co-director of the Center for Addiction Medicine at Massachusetts General Hospital. He is the MGH Trustees Chair in Addiction Medicine and a professor of psychiatry at Harvard Medical School. Dr. Wilens’ research interests include the relationship among attention deficit/hyperactivity disorder (ADHD), bipolar disorder, and substance use disorders, embedded health care models, and the pharmacotherapy of ADHD across the lifespan. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E274 - Busting Myths About Antipsychotics with Dr. Jonathan Meyer
01/28/2026
E274 - Busting Myths About Antipsychotics with Dr. Jonathan Meyer
In this episode, Dr. Andy Cutler speaks with Dr. Jonathan Meyer to dispel common myths about antipsychotic treatment, from concerns about sedation, personality change, and brain effects to misunderstandings about safety, long-acting injectables, and clozapine. The discussion focuses on what the evidence actually shows about efficacy, risk, and recovery, and how clinicians can communicate more clearly and confidently with patients and families. Jonathan Meyer, MD, DLFAPA, is a Voluntary Clinical Professor of Psychiatry at the University of California, San Diego. He serves as a Senior Academic Advisor to the California Department of State Hospitals, is a psychopharmacology consultant to the first episode psychosis program at Balboa Naval Medical Center, and has published extensively on psychopharmacology, including co-authoring The Clozapine Handbook, The Clinical Use of Antipsychotic Plasma Levels, and The Lithium Handbook with Dr. Stephen Stahl. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E273 - Busting Myths About Antidepressants with Dr. Jeffrey Strawn
01/14/2026
E273 - Busting Myths About Antidepressants with Dr. Jeffrey Strawn
In this episode, Dr. Andy Cutler and Dr. Jeff Strawn unpack common misconceptions that complicate real-world use of antidepressants. They review evidence on efficacy, suicidality risk, mechanisms, and early side effects, and discuss how to navigate hesitancy and misinformation. The conversation also addresses when to start medication, how to balance caution with timely intervention in youth, and practical ways to strengthen trust and therapeutic alliance. Jeffrey R. Strawn, MD, FAACAP, is a Professor of Psychiatry, Pediatrics, and Clinical & Translational Pharmacology at the University of Cincinnati (UC) in Cincinnati, Ohio. He is the Director of the UC Anxiety Disorders Research Program and the Associate Vice Chair of Research in the Department of Psychiatry & Behavioral Neuroscience at UC. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and EMA Wellness. He is a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Zhang K et al. Functional connectivity predicting transdiagnostic treatment outcomes in internalizing psychopathologies. JAMA Netw Open 2025;8(9):e2530008. doi: Lagerberg T et al. Selective serotonin reuptake inhibitors and suicidal behaviour: a population-based cohort study. Neuropsychopharmacology 2022;47(4):817-23. doi: Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E272 - Our Most Downloaded Episode of 2025: Borderline Personality Disorder with Dr. Carla Sharp
12/31/2025
E272 - Our Most Downloaded Episode of 2025: Borderline Personality Disorder with Dr. Carla Sharp
As 2025 comes to an end, we revisit our most downloaded episode of the year. Join Dr. Andy Cutler and Dr. Carla Sharp as they explore the current conceptualization of borderline personality disorder (BPD), including diagnostic challenges, evidence-based treatments, and strategies to reduce stigma by framing BPD as a treatable condition. The conversation also highlights recent updates to the APA’s BPD guidelines and what they mean for clinical practice. Carla Sharp, PhD is a distinguished clinical psychologist specializing in developmental psychopathology, particularly borderline personality disorder (BPD). She is a professor in the Clinical Psychology Doctoral Program and serves as the Associate Dean for Faculty and Research at the University of Houston. Additionally, she directs both the Adolescent Diagnosis, Assessment, Prevention, and Treatment Center and the Developmental Psychopathology Lab at the university. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E271 - A Look Back at This Year in Psychopharmacology with Dr. Roger McIntyre
12/17/2025
E271 - A Look Back at This Year in Psychopharmacology with Dr. Roger McIntyre
Join Drs. Andy Cutler and Roger McIntyre as they discuss the most significant advancements in psychopharmacology over the past year. Their conversation highlights groundbreaking developments and innovations in the field of psychiatry. Roger McIntyre, MD, FRCPC, is a globally recognized psychiatrist and psychopharmacologist who holds pivotal roles in academia, research, and leadership. His research primarily focuses on the phenomenology, neurobiology, and development of novel therapeutics for mood disorders. Dr. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Thanarajah ES et al. Soft drink consumption and depression mediated by gut microbiome alterations. JAMA Psychiatry 2025;82(11):1095–1102. doi: Durgam S et al. Lumateperone as adjunctive therapy in patients with major depressive disorder: results from a randomized, double-blind, phase 3 trial. J Clin Psychiatry 2025;86(4):25m15848. doi: Hendershot CS et al. Once-weekly semaglutide in adults with alcohol use disorder: a randomized clinical trial. JAMA Psychiatry 2025;82(4):395–405. doi: Aron L et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature 2025;645:712–21. doi: Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E270 - (CME) Complex Depression: Treating Beyond the Standard Algorithm
12/03/2025
E270 - (CME) Complex Depression: Treating Beyond the Standard Algorithm
In this CME episode, Dr. Andy Cutler talks with Drs. Stephen Stahl and Roger McIntyre about recognizing and managing complex depression, particularly major depressive episodes with mixed or anxious features. They discuss how these specifiers affect diagnosis, symptom severity, and treatment response, and explore evidence-based strategies for optimizing outcomes through individualized and adjunctive approaches. Create a free NEI guest account and obtain CME/CE by participating in this activity here: Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E269 - (CME) Navigating Complexity: Personalized Treatment Approaches Across the Stages of Bipolar I Disorder
11/26/2025
E269 - (CME) Navigating Complexity: Personalized Treatment Approaches Across the Stages of Bipolar I Disorder
In this CME episode, Dr. Andy Cutler and Dr. Christoph Correll discuss the complexities of managing bipolar disorder, with a focus on recognizing and treating mixed states. They address overlapping manic and depressive symptoms, comorbidities, and the importance of shared decision-making, family involvement, and patient education. The conversation also explores strategies to improve adherence, the impact of substance use, and the value of a collaborative, individualized approach to long-term stability and recovery. Create a free NEI guest account and obtain CME/CE by participating in this activity here: Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E268 - 2025 NEI Fall Congress Extended Q&A with Drs. Brittany Albright, Lori Davis, Leslie Citrome, and Jeffrey Strawn
11/19/2025
E268 - 2025 NEI Fall Congress Extended Q&A with Drs. Brittany Albright, Lori Davis, Leslie Citrome, and Jeffrey Strawn
This episode includes extended Q&A sessions that address your unanswered questions from the following presentations delivered at the 2025 Fall Congress in Colorado Springs, Colorado: (00:22) A Discussion of Substance: Supporting Meaningful Improvements in the Lives of Patients Struggling With Substance Use Disorders by Brittany Albright, MD, MPH and Hara Oyedeji, DNP, PMHNP-BC (Q&A with ) (34:08) Nightmares and Brainscapes: Emerging Therapeutic Avenues in the Treatment of PTSD by Lori Davis, MD and Andrew Cutler, MD (Q&A with ) (47:43) Sex, Pudge, and Eyes That Close: Strategies to Address Common Psychotropic–Induced Tolerability Issues by Leslie Citrome, MD, MPH and Andrew Cutler, MD (Q&A with ) (55:00) When Less Is More: Strategies for Deprescribing Psychotropic Medications by Jeffrey Strawn, MD and Kari Franson, PharmD, PhD, BCPP (Q&A with ) Never miss an episode!🎙SUBSCRIBE to the NEI Podcast – available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E267 - Re-release: Diagnosis, Treatment, and Pathophysiology of Catatonia with Dr. Joan Striebel
11/05/2025
E267 - Re-release: Diagnosis, Treatment, and Pathophysiology of Catatonia with Dr. Joan Striebel
In recognition of Stress Awareness Week, the NEI Podcast revisits a vital conversation with Dr. Joan Striebel about the syndrome of catatonia—a condition that can emerge from profound psychological or physiological stress. Dr. Andy Cutler and Dr. Striebel discuss its dynamic presentation, the importance of treating underlying causes, and why clinicians should maintain a high index of suspicion when evaluating complex or unexplained psychiatric symptoms. This re-release highlights key insights to help clinicians recognize and manage catatonia more effectively in practice. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E266 - ADHD Treatment in the Real World: Prescribing Trends and Patient Outcomes with Dr. Ryan Sultán
10/22/2025
E266 - ADHD Treatment in the Real World: Prescribing Trends and Patient Outcomes with Dr. Ryan Sultán
In this episode, Dr. Andy Cutler talks with Dr. Ryan Sultán about the evolving landscape of ADHD—why diagnoses and prescriptions have risen across age groups, what recent prescribing data reveal, and how these trends align with real-world clinical experience. They explore how ADHD medications affect not just symptoms but broader outcomes like school, work, and safety, while also addressing concerns about overdiagnosis, misuse, and disparities in access to care. Dr. Ryan Sultan is a board-certified adult and and assistant professor at Columbia University Irving Medical Center and the New York State Psychiatric Institute. He is the Medical Director of NYC-based , where he assesses and treats patients using a combination of psychological, social, environmental, and pharmacological modalities. Integrative Psychiatry also provides . As an , he conducts extensive ADHD research with a focus on using big data to improve ADHD treatment in real world settings, advocating for non-pharmacological interventions such as cognitive behavioral therapy (CBT) for ADHD, coaching, and digital tools as a foundational treatment that precedes or supplements medication. He approaches with a nuanced understanding of the current misuse and overdiagnosis crisis, and addresses this issue through careful assessment and monitoring. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E265 - Beyond Dopamine: Evolving Strategies for Antipsychotic Switching in Schizophrenia with Dr. Peter Weiden
10/08/2025
E265 - Beyond Dopamine: Evolving Strategies for Antipsychotic Switching in Schizophrenia with Dr. Peter Weiden
In this episode, Dr. Andy Cutler interviews Dr. Peter Weiden about when and how to switch antipsychotics in schizophrenia, tackling both the pitfalls and opportunities clinicians face in practice. They also explore how xanomeline–trospium has opened the door to treatments beyond dopamine and what this shift means for the future of care. Peter J. Weiden, MD, is a psychiatrist and internationally recognized expert in the pharmacologic treatment of schizophrenia. His research and clinical work have focused on antipsychotic effectiveness, switching strategies, and medication adherence, with a particular emphasis on optimizing long-term outcomes for patients. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E264 - (CME) Pediatric Bipolar Disorder: Differentiation, Treatment, and Transitioning to Adult Care
09/24/2025
E264 - (CME) Pediatric Bipolar Disorder: Differentiation, Treatment, and Transitioning to Adult Care
In this CME episode, Dr. Andy Cutler speaks with Dr. Manpreet Singh, the Robert H. Putnam Endowed Chair in Bipolar Research and Treatment at UC Davis, about the challenges of diagnosing and treating pediatric bipolar disorder. Dr. Singh shares evidence-based strategies for treatment, management of bipolar depression and medication side effects, and best practices for long-term care and transitioning youth into adult services. NEI Members can earn CME/CE by participating in this activity here: Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E263 - Men’s Mental Health and the Transition to Fatherhood with Dr. Dan Singley
09/10/2025
E263 - Men’s Mental Health and the Transition to Fatherhood with Dr. Dan Singley
In this episode, Dr. Andy Cutler interviews Dr. Dan Singley about the unique challenges men face in recognizing, expressing, and seeking care for their mental health. They explore how norms around masculinity influence help-seeking behavior and contribute to men’s heightened risk of suicide. The conversation also highlights the underrecognized issue of paternal perinatal depression, its impact on family dynamics, and strategies clinicians can use to better screen, engage, and support new fathers. Dr. Daniel Singley, PhD, is a clinical psychologist and expert in men’s mental health, with a particular focus on the transition to fatherhood and perinatal mental health for men. He is the founder and director of the Center for Men’s Excellence in San Diego, where he provides therapy, consultation, and training centered on men’s psychological development and gender-sensitive care. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources The Center for Men’s Excellence – Society for the Psychology of Men and Masculinities – Postpartum Support International – Man Therapy – Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E262 - Psychiatric and Neurological Symptoms of Long COVID with Dr. Roger McIntyre
08/27/2025
E262 - Psychiatric and Neurological Symptoms of Long COVID with Dr. Roger McIntyre
In this episode, Dr. Andy Cutler interviews Dr. Roger McIntyre about the growing recognition of Long COVID and its wide-ranging neuropsychiatric manifestations. They discuss the role of neuroinflammation in its pathophysiology, the impact of these symptoms on patients’ daily functioning, and both current and emerging treatment approaches. Dr. Roger McIntyre is a globally recognized psychiatrist and psychopharmacologist who holds pivotal roles in academia, research, and leadership. His research primarily focuses on the phenomenology, neurobiology, and development of novel therapeutics for mood disorders. Dr. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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E261 - When Trauma Compounds: Clinical Strategies for PTSD and mTBI in Veterans with Dr. Pamela Wall
08/13/2025
E261 - When Trauma Compounds: Clinical Strategies for PTSD and mTBI in Veterans with Dr. Pamela Wall
In this episode, Dr. Andy Cutler interviews Dr. Pamela Wall about the complex intersection of PTSD and mild traumatic brain injury (mTBI) in veterans. They explore how military culture influences the experience and treatment of trauma, the challenges of distinguishing overlapping symptoms, and evidence-based strategies for assessment and intervention. Tune in for practical insights, clinical pearls, and resource recommendations for improving care in this uniquely vulnerable population. Pamela Wall, PhD, PMHNP-BC is an associate professor in the College of Nursing at Rosalind Franklin University and maintains a clinical practice at a neuropsychiatric clinic in Fairfax, VA. She has extensive experience working with adult psychiatric mental health populations, and her research has focused on PTSD, mTBI, and sleep disorders in deployed military service members. Dr. Wall served 20 years on active duty as a Nurse Corps Officer in the United States Navy. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: Stay updated with and join our conversations on social. Follow us on: YouTube: Instagram: LinkedIn: Facebook: X:
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