Thomas Stieglitz Discusses Material Choice in Implant Development
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
Release Date: 03/22/2021
Francesco Petrini - SensArs and the Future of Sensory Neuroprosthetics for Diabetic Neuropathy
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Francesco Petrini, co-founder and CEO of SensArs, to discuss how intraneural stimulation could help restore sensation in patients with diabetic neuropathy. Francesco explains how loss of feeling in the feet can lead to unnoticed injuries, chronic wounds, and even amputations - and why rebuilding sensory feedback could dramatically improve quality of life. The conversation explores SensArs’ approach to neuromodulation and what it takes to translate sensory neuroprosthetics into real-world clinical impact. Top...
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Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Dr. , , whose lab uses intracranial brain recordings to study the biology of human cognition. Ignacio shares how cutting-edge neurotechnology like iEEG can reveal the neural dynamics behind decision-making, risk, memory, and brain states - and how those insights could unlock more targeted neuromodulation therapies for psychiatric disorders such as depression and anxiety. Top 3 Takeaways: Epilepsy patients undergoing seizure monitoring often have 100-200 electrodes implanted in their brains and may...
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Dr. Ladan Jiracek - My PhD Defense, LCP Neural Implants, and What’s Next
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this solo episode of the Neural Implant Podcast, host Dr. Ladan Jiracek shares the story behind finally completing his PhD at the University of Florida - from the highs of passing his dissertation defense to the long, frustrating, and deeply technical journey of developing liquid crystal polymer (LCP)-based neural implants. I break down why LCP is so promising for long-term implantable devices, how delamination and bonding challenges became the core focus of his dissertation, and what it took to fabricate ultra-thin polymer electrodes approaching “biological invisibility.” I also...
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Paul Goode: Implantable Glucose Monitoring—and a Neural Interface Twist
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode, Paul Goode (Glucotrack) dives into the next wave of continuous glucose monitoring: an active, fully implantable CGM designed to deliver long-term, pacemaker-style reliability without external wearables. We discuss first-in-human progress, why implantables may change diabetes care at home, and a fascinating neural angle—how similar chemistry and form factors could be adapted to epidural glucose sensing and even paired with neural recording electrodes to capture metabolic and neural data together. If you care about closed-loop systems, chronic implants, or bridging...
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Fabio Boi on Corticale’s Ultra-Dense, Minimally Invasive Brain Interfaces
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, I speak with , Co-Founder and CSO of , an Italian neurotech company that is redefining the landscape of brain-computer interfaces. Corticale is pioneering a new generation of minimally invasive, CMOS-based neural implants that can record from thousands of neurons simultaneously—introducing their flagship technology, SiNAPS. Fabio walks us through how SiNAPS achieves single-cell resolution recordings via its 1024-electrode array, enabling high-fidelity access to both action potentials and local field potentials deep within cortical tissue. We...
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Ben Woodington on Coherence Bio's Revolutionary Cancer Reprogramming Approach
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, we sit down with , co-founder of , a groundbreaking medical technology company pioneering a new frontier in cancer treatment. By integrating neurotechnology, neurobiology, and machine learning, Coherence is building a platform that doesn't just fight cancer—it manages it in real time. Ben shares how Coherence is moving beyond the traditional "cut, burn, poison" model of oncology, and instead focusing on precision neuromodulation to monitor and control cancer progression—offering hope for 24/7 adaptive treatment with fewer side effects and...
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Dr Christian Wende on European IP Strategy, Medtech Patents & the UPC
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode, we dive into the world of European intellectual property and medtech innovation with , a German and European Patent Attorney specializing in medical technology at . With a background in mechanical engineering, a Ph.D. in liver dialysis research, and a Master of Laws in European IP law, Christian brings a rare and powerful combination of technical, legal, and clinical insight. We explore how startups and investors should think about IP strategy in Europe, the impact of the new Unified Patent Court (UPC), the nuances between U.S. and EU patent landscapes, and how IP due...
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Inside AIMD: Building the Future of Implantable Devices with Nicolas Barabino & Antoni Ivarra
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this special episode recorded after the workshop in Barcelona, I talk with and , two of the key organizers behind the . We dive into the vision behind this growing event, which brings together top researchers, engineers, clinicians, and entrepreneurs to explore the cutting edge of implantable medical devices. Nicolas and Antoni share insights on the evolution of AIMD technologies, the role of multidisciplinary collaboration, and how this annual workshop is shaping the next generation of innovators. We also touch on the challenges that startups face in the space—regulatory hurdles, IP...
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Chad Andresen on Lunosa’s Injectable Neurostimulator and Lessons from Stimwave
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode, we sit down with , Chief Business Officer of , to explore a groundbreaking approach to treating obstructive sleep apnea. Lunosa is developing a self-expanding, injectable neurostimulator that aims to replace invasive facial surgeries with a minimally invasive, high-impact solution — tapping into a $10 billion market. Chad also reflects on his time at , a pioneering neuromodulation company that saw both innovation and controversy. He shares insights from testifying against Stimwave’s former CEO, lessons learned from the company’s collapse, and how those experiences shape...
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Frederik Ceyssens and the ReVision Implant Team: Building a Visual Cortical Prosthesis to Restore Sight
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this special on-location episode recorded in Leuven, Belgium, we sit down with the co-founders and technical leaders of — (CEO), (CTO), and (CSO). The team shares their journey developing a high-density, intracortical visual prosthesis aimed at restoring vision for the blind. From developing reliable insertion technology to achieving long-term biocompatibility in nonhuman primate models, ReVision Implant is at the forefront of neurotech innovation. Tune in to hear about their challenges, breakthroughs, and what’s next in the race to cure blindness through brain stimulation. This...
info_outlineThomas Stieglitz is a professor at the University of Freiburg where he does research on the development of biocompatible construction and interconnection technology as well as the use of microsystems for neuroprosthesis and neuromodulation. Thomas Stieglitz is also on the scientific-technical advisory board of Cortec- Neuro. In today’s episode, Thomas talks about is work in neuromodulation, shares insights on the best materials for implant development and finally, share some of the challenges faced with neuroprosthesis.
Top three takeaways:
- Polymers have a lot of advantages as materials for implants. They are more flexible than Silicon although they are not as flexible as
- Making the ideal implant takes targeting very well. And tailoring functionality to needs. General-purpose implants will not work
- 3d printing has injected a new wave of possibility in the world of prosthetics
[0:00] Ladan introduces the episode and the guest, Thomas Stieglitz
[3:30] Thomas Stieglitz talks about the different disciplines of Neural interfaces / neural electrodes and the motivation for his work.
[8:00] Polymers have a list of advantages. One is that they are more flexible than Silicon. Another is their variety of shapes.
[9:20] Silicon has advantages in certain areas. It is the best technology for recording and stimulating
[13:00] Thomas Stieglitz talks about the P dot polymer, what it is and how it works.
[16:35] Thomas Stieglitz talks about the ideal implant and describes the most robust and reliable implant you can have
[18:50] It will be an exciting development to see a paper on the comprehensive model of a digital twin of implant failure nodes.
[23:30] In Europe, without any institution like the IDE, there is no seamless way to get implants to human trials without negotiating with a legal entity to prove potential for success
[26:45] Thomas discusses his role at Cortec-neuro
[27:35] There are good and bad aspects of working with implants. Sometimes implants are damaged because Surgery personnel are not careful enough or rehabilitation personnel don’t follow the manual and break the connectors.
[30:00] “We believe that now, that we can predict with the data that we have and some additional in vitro experiments that we did after getting them back to proving something that those pieces can survive up to 5 billion of stimulation, pulses.”