loader from loading.io

Prof Marom Bikson discusses his work with Transcranial Direct Current Stimulation

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Release Date: 05/03/2021

Samuel Browd | Venture Studios, BCI, and Digital Neurosurgery show art Samuel Browd | Venture Studios, BCI, and Digital Neurosurgery

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Dr. is a pediatric neurosurgeon, at the University of Washington, and Co-CEO/Chief Medical Officer of , a venture studio focused on neurological technologies. In this episode, we discuss his path from early neuroscience research and pediatric neurosurgery into device development, brain-computer interfaces, and the challenge of moving promising neurotechnology from universities into real clinical use. We also explore the idea of “digital neurosurgery”: how neurosurgery still captures enormous amounts of valuable data in analog or siloed ways, why AI and computer vision may reshape...

info_outline
Jin Hyung Lee | Visualizing Brain Circuits with EEG and AI show art Jin Hyung Lee | Visualizing Brain Circuits with EEG and AI

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is an associate professor at Stanford and founder of , a company translating years of brain circuit research into clinical software for neurological care. In this episode, we discuss how her team thinks about the brain as a circuit system, why neurological disorders can be difficult to diagnose with today’s tools, and how LVIS’s NeuroMatch platform aims to use EEG data to visualize brain network function in a more accessible way. We also talk about why EEG remains clinically useful despite its limitations, how software can help clean and interpret noisy brain signals, and why Dr. Lee...

info_outline
JB (NextSense) | Ear EEG Earbuds That Measure and Improve Sleep show art JB (NextSense) | Ear EEG Earbuds That Measure and Improve Sleep

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, , founder and CEO of , discusses how his team is transforming ordinary-looking earbuds into wearable brain interfaces capable of recording EEG directly from the ear. Originally incubated inside Google X before spinning out as an independent company, NextSense combines consumer electronics with neuroscience to monitor sleep, enhance slow-wave activity through closed-loop audio stimulation, and explore future applications ranging from epilepsy forecasting to Alzheimer's disease monitoring. We also discuss the engineering challenges of ear EEG,...

info_outline
Ali Samiian - The Hidden Barrier That Kills Neurotech Startups show art Ali Samiian - The Hidden Barrier That Kills Neurotech Startups

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , founder of , about one of the most overlooked challenges in neurotechnology and medical devices: reimbursement. Ali has spent over 20 years working across pharma, medical devices, and neuromodulation, including leadership roles at Abbott, Novartis, and Cala Health, where he helped secure reimbursement for a first-in-class wearable neuromodulation therapy for essential tremor. In this conversation, Ali explains why FDA approval alone is often not enough for a company to succeed, and why coding, coverage, and...

info_outline
Ellyn Ito - MindVibe and Non-Invasive Vagus Nerve Stimulation for Stress and Focus show art Ellyn Ito - MindVibe and Non-Invasive Vagus Nerve Stimulation for Stress and Focus

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , CEO and co-founder of , about their wearable neurotechnology platform and flagship product, MindVibe. This non-invasive device combines vagus nerve stimulation and acupressure-based neuromodulation to help regulate the body’s stress response and improve overall wellness. Ellyn shares how MindVibe is designed to promote calm, enhance focus, and improve sleep quality through ultra-low electrical stimulation that users don’t even feel. The conversation explores the science behind multi-mode stimulation, why...

info_outline
Dr. Christian Iorio-Morin - From Gamma Knife to Neuroprosthetics: The Future of Functional Neurosurgery show art Dr. Christian Iorio-Morin - From Gamma Knife to Neuroprosthetics: The Future of Functional Neurosurgery

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek speaks with , functional neurosurgeon and professor at the , about the evolving landscape of neurosurgery—from treating movement disorders and chronic pain to pushing the boundaries of paralysis recovery. Christian shares insights from his clinical work using gamma knife surgery, neuromodulation, and microvascular techniques, as well as his leadership on the RE-MOVE project, a large-scale initiative aiming to restore movement by reconnecting the brain and spinal cord through implantable technology. The conversation...

info_outline
Omari Bouknight - Resonant Link Medical and the Next Generation of Wirelessly Powered Neurotech show art Omari Bouknight - Resonant Link Medical and the Next Generation of Wirelessly Powered Neurotech

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with , CEO of , to explore how advances in wireless power transfer are reshaping the future of implantable medical devices. Omari shares how traditional power limitations have historically constrained device design—and how Resonant Link Medical’s technology is turning power into an enabler, allowing for smaller, smarter, and longer-lasting implants. The conversation dives into real-world applications across neurotech and beyond, including how faster, more efficient wireless charging could unlock advanced...

info_outline
Francesco Petrini - SensArs and the Future of Sensory Neuroprosthetics for Diabetic Neuropathy show art Francesco Petrini - SensArs and the Future of Sensory Neuroprosthetics for Diabetic Neuropathy

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Francesco Petrini, co-founder and CEO of SensArs, to discuss how intraneural stimulation could help restore sensation in patients with diabetic neuropathy. Francesco explains how loss of feeling in the feet can lead to unnoticed injuries, chronic wounds, and even amputations - and why rebuilding sensory feedback could dramatically improve quality of life. The conversation explores SensArs’ approach to neuromodulation and what it takes to translate sensory neuroprosthetics into real-world clinical impact. Top...

info_outline
Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain show art Ignacio Sáez - Neurotechnology for Cognition: Recording and Modulating the Human Brain

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this episode of the Neural Implant Podcast, host Dr. Ladan Jiracek sits down with Dr. , , whose lab uses intracranial brain recordings to study the biology of human cognition. Ignacio shares how cutting-edge neurotechnology like iEEG can reveal the neural dynamics behind decision-making, risk, memory, and brain states - and how those insights could unlock more targeted neuromodulation therapies for psychiatric disorders such as depression and anxiety.  Top 3 Takeaways:  Epilepsy patients undergoing seizure monitoring often have 100-200 electrodes implanted in their brains and may...

info_outline
Dr. Ladan Jiracek - My PhD Defense, LCP Neural Implants, and What’s Next show art Dr. Ladan Jiracek - My PhD Defense, LCP Neural Implants, and What’s Next

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In this solo episode of the Neural Implant Podcast, host Dr. Ladan Jiracek shares the story behind finally completing his PhD at the University of Florida - from the highs of passing his dissertation defense to the long, frustrating, and deeply technical journey of developing liquid crystal polymer (LCP)-based neural implants. I break down why LCP is so promising for long-term implantable devices, how delamination and bonding challenges became the core focus of his dissertation, and what it took to fabricate ultra-thin polymer electrodes approaching “biological invisibility.” I also...

info_outline
 
More Episodes

Marom Bikson is a Biomedical Engineer. He is a Professor at the City College of New York City and also the co-director of the Neural Engineering Group. Marom has been at the City College of New York for over 15 years. He has a B.Sc in Biomedical Engineering from John Hopkins University and a PhD from Case Western University Cleveland. He cofounded Soterix Medical. Marom's research group studies the effects of electricity on the human body and applies this knowledge toward the development of medical devices and electrical safety guidelines.

In today’s episode, Marom talks about his work with Transcranial Direct Current Stimulation and how it works. He also talks about his work with NC Neuromodulation and Soterix Medical

 

Top three takeaways:

  1. Transcranial means, through the cranium. And the thing that you're stimulating is targets inside the cortex. So you're trying to identify targets centrally that you think that you can activate. To lead to different therapeutic outcomes.
  2. TDCS works by the application of direct electrical current to electrodes placed on the scalp.
  3. “A lot of times when we think about TDCS, we think about changing the sensitivity. And then the question comes in with a sensitivity to what. Often TDCS is combined with other forms of therapy, like behavioural therapy, or physical therapy

 

[0:00] Ladan introduces the episode and the guest, Prof Marom Bikson

 

[1:50] Marom introduces himself and his work

 

[2:30] Marom discusses the wave of persistent COVID symptoms that are referred to as neuro COVID and talks about some of the work he and his colleagues are doing around it.

 

[4:50] Marom describes how Transcranial Direct Current Simulation work.
“ transcranial means, through the cranium. And the thing that you're stimulating is targets inside the cortex. So you're trying to identify targets centrally that you think that you can activate. To lead to different therapeutic outcomes.”

 

[6:00] Marom discusses papers documenting the use of TDCS in different therapeutic areas such as depression and pain.

 

[7:45]  Currently, there is no FDA clearance for TDCS in the US so most of the work now happens in clinical trials. 

 

[10:10] TDCS works by the application of direct electrical current to electrodes placed on the scalp.

 

[13:40] “A lot of times when we think about TDCS, we think about changing the sensitivity. And then the question comes in with a sensitivity to what. Often TDCS is combined with other forms of therapy, like behavioural therapy, or physical therapy.”

 

[16:20] Marom talks specifically about his research and some of his breakthroughs.

 

[20:50] Marom talks about his company, Soterix medical; the background for starting the company and what kind of problems they are solving

 

[27:40] Marom discusses NYC Neuromodulation which he co-founded.

“NYC neuromodulation has now run. I think about five times the last time was an online version. The two times before that we worked with other organizations, the North American neuromodulation society was partnered for one and neuromodulation of science was partnered for another.”

 

[33:50] So what are some Big pieces of advice that you would say to other neural engineers?

“ If you're loving what you're doing, then that probably means you're on the right path.”