Dan Brounstein on how closed loop Spinal Cord Stimulation has better efficacy at Saluda
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
Release Date: 10/17/2022
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
I n this episode of the Neural Implant Podcast, host Ladan welcomes and from , an engineering services company based in Uruguay. They discuss their work in firmware, hardware, and software development for medical devices, emphasizing their specialization in wireless communications and test automation. They also explain the benefits of contract engineering, the challenges they face, and highlight an exciting project involving an injectable neurostimulator. The conversation covers the history of neurotechnology development in Uruguay, the process and dynamics of working with clients, and...
info_outline Stephen Ho: Exploring Neurotech in Cinema with the Neurratives PodcastNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Today's guest is from Blackrock Microsystems. While we've featured Blackrock guests before, Stephen's appearance today is driven by his podcast, , where neurotech-inspired movies are reviewed and discussed. Top 3 Takeaways: "Our goal for the podcast isn't necessarily to be overly technical, requiring a neuroscience degree to understand. We're often deep in the subject matter and may get a bit jargony, but broadly, we aim to be accessible without pretending to be accomplished neuroscience researchers." “Due to the subject's nature, movies dealing with neuroscience themes...
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is a University of Michigan PhD graduate working on thin film neural implants but has since transitioned into the legal side of things having passed his bar exam and working with . This interview took almost 2 years to get done but we're glad we were able to do it! Top 3 Takeaways: "I think the main thing I'll say is you don't undermine your valuation by not having an informed and intentional patent strategy, and you don't have to go cheap. You know, I feel that you have to bootstrap, but if you work with certain law firms that are very entrepreneurial friendly, and my...
info_outline Paul Le Floch: Pioneering Neural Implant Materials with AxoftNeural Implant podcast - the people behind Brain-Machine Interface revolutions
"Welcome to today's episode! Our guest, , co-founder and CEO of , brings innovation to neural implants. With roots in France and a Harvard PhD, he's leading groundbreaking work. Welcome, Paul!" Top 3 Takeaways: "It's a good time to ask the question: What if we could develop solutions tailored for this problem instead of borrowing from the semiconductor industry? That's what Axsoft is about. We emphasize developing soft materials that offer better long-term biocompatibility. Additionally, these materials are suitable for micro and nano fabrication and remain stable inside the...
info_outline Christine Schmidt: Pioneering Regenerative Neural Tissue EngineeringNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Today’s guest is who is a share who works in regenerative neural tissue engineering. Top 3 Takeaways: "We're trying to create scaffolds that can be templates for the body to repair itself, to grow around, and ultimately become natural tissue, seamlessly integrating with the body's own." "Other faculty were discouraging. This is because academia tends to prioritize scholarly pursuits such as papers and grants, often undervaluing applied work and its real-world applications." "Our clinical collaborator actively participated in the lab alongside Sarah. Together, they would work on...
info_outline Bioel 2024 Conference panel with Drs Jon Viventi, Tracy Cui, Ellis Meng, and Ivan MinevNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Welcome to the Neural Implant Podcast! In this episode, the podcast team presents a live panel recording from the Bio L Conference at the International Winter School on Bioelectronics in Austria in March 2024. Hosted by Ladan, the panel discusses various types of neural implants with esteemed guests: Drs . (LCP neural implants), (PEDOT electrode coatings), (parylene neural implants), and (PDMS neural implants). Tune in as they explore the fascinating world of soft implantable electrodes and brain-nervous system interfaces. Top 3 Takeaways: “In the next five or 10 years, I...
info_outline Carles Garcia-Vitoria: Pioneering Pain Relief with Intrathecal Spinal Cord Stimulation with SpinallyNeural Implant podcast - the people behind Brain-Machine Interface revolutions
In today's episode, we're joined by , a seasoned pain physician with a unique approach to his work. With extensive experience in regional anesthesia and pain management, Carles shares insights gained from his years of practical experience as he pursues his PhD in Spain. Top 3 Takeaways: "We believe we have the opportunity to target the site of action more effectively. That's why we've founded Spinally, the startup we're currently leading. Our goal is to pioneer intrathecal spinal cord stimulation." "The Dura Mater is highly elastic, closing approximately 80-90% within the first 30...
info_outline Steve Goetz: Revolutionizing Mental Health Treatment as CTO of Motif NeurotechNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is now the Chief Technology Officer at which is developing a minimally invasive neural implant for the treatment of depression and mental health issues. Steve was at Medtronic for 26 years before moving over to the startup landscape. Top 3 Takeaways: "Starting a big program that you don't know how to finish is a very expensive endeavor, and so you want to really shake out all the science risk, all the technology risk, be pretty sure you can execute a thing before you turn on that big engine because it's expensive once you go" "We know stimulation of the dorsal lateral...
info_outline Eric Glowacki on cutting edge neural implant fabricationNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is a research group leader at the Central European Institute of Technology () located in Brno, Czech Republic. There he studies neural implant fabrication and materials specializing in silicon, parylene, and polyimide devices. He has also started to designs and fabricate devices on a contract basis for other research groups and companies. And, his institute is the one that has been recently sponsoring the podcast! This podcast is sponsored by CEITEC Nano, check out their Neurotech Device Manufacturing Capabilities Top 3 Takeaways: "You can just buy stuff on the internet very simple red...
info_outline Gene Fridman on his freeform stimulator allowing for more neural stimulation possibilitiesNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is an Associate Professor in the Department of Otolaryngology Head and Neck Surgery and also has appointments with the Department of Biomedical Engineering and the Department of Electrical and Computer Engineering. His research is in the areas of bioinstrumentation and neural engineering. In this episode we talk about his freeform nerual stimulator which allows for DC and any other waveforms without any electrolytic effects on the electrodes. This opens up many possibilities for neural stimulation. We also talk about his startup Aidar which is like a 'tricorder' all-in-one medical diagnostic...
info_outlineDan Brounstein is Chief Strategy Officer at Saluda Medical where he is using his 15 years of Spinal Chord Stimulator experience to help deliver closed-loop pain relief directly to the spinal cord.
***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services here***
Top 3 Takeaways:
- "We're stimulating with milliamps and we're trying to measure in microvolts, and we always use the analogy trying to listen to a pin drop next to a shotgun shot"
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"There's a lot of literature on loss of efficacy? It's just a therapy issue. When you deliver open-loop therapies blind across a neural target, you're ultimately going to create, over-stimulation in a lot of times under stimulation. On top of that, over time things change"
- "Patients come in between four and five times a year on average in perpetuity with open loop systems"
0:45 " Do you want to introduce yourself and the company better than I just did?"
6:00 "Your guys' device reprograms on its own? And then what signals does it take in and how does it change the stimulation patterns based on that?"
9:00 Iris Biomedical ad sponsorship
9:45 "What is your input and output for your guys' device?"
11:45 "In February of 2023, you guys got FDA approval for this. Do you wanna talk a little bit about this?"
14:15 "Is it like 5% better than open loop or is that something that's gonna be coming out published later?"
17:00 "Is there another indication?"
18:15 "The last I guess seven years for you has been very exciting. Is there anything on the horizon for the next seven years?"
20:15 "You guys have 300 people and have raised 200 million. What's it like working in such a big company"
22:45 "Is it getting too big for you?"
23:45 "What advice do you have for people in your situation?"
26:00 "Is there anything that we didn't talk about that you wanted to mention?"