Dan Brounstein on how closed loop Spinal Cord Stimulation has better efficacy at Saluda
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
Release Date: 10/17/2022
Neural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, we’re joined by , CEO of , a consulting firm that specializes in helping MedTech companies navigate the complex journey from concept to commercialization. With over two decades of experience across regulatory strategy, product development, and market access, Nathan shares invaluable insights into the critical steps for MedTech startups and established companies looking to succeed in today’s competitive landscape. Tune in as we discuss the unique challenges of the neurotech industry, strategic consulting for MedTech ventures, and how Nunex is...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, we welcome Dr. Eugene Daneshvar, founder of Black Swan Intellectual Property (BSIP), a boutique law firm specializing in intellectual property for neurotech and medtech innovations. With a background in biomedical engineering and law, Eugene has a unique perspective on protecting the cutting-edge ideas that drive the future of healthcare technology. After years of working at a larger firm, Eugene founded BSIP to provide more accessible, fair, and transparent pricing for IP services, moving away from the traditional hourly billing model. In...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode, we welcome , a leading expert in ASIC design and professor at the , Germany. With a distinguished career in microelectronics, Dr. Ortmanns has contributed extensively to the development of integrated circuits for biomedical applications. He shares insights into the critical role of ASIC (Application-Specific Integrated Circuit) design in advancing neurotech implants, focusing on low-power, high-speed circuits that are essential for optimizing the performance and reliability of these devices. Dr. Ortmanns also discusses the challenges and future of circuit integration in...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Ladan Jiracek engages in an insightful dialogue with , founder and CEO of . The discussion covers Cognixion's pioneering augmented reality headset with EEG sensing, designed to enhance communication for individuals with speech and motor challenges. Andreas describes the journey from creating a speech augmentation device to developing a versatile platform, the Axon-R, which is now being utilized by health systems and researchers for various clinical applications. They explore the platform's form factor, capabilities, and its role in empowering...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
In this episode of the Neural Implant Podcast, host Ladan speaks with , the Director of Education Outreach for the and a Research Assistant Professor in the Department of Neurological Surgery at the University of Miami. They discuss the Miami Project's work, particularly in spinal cord injury research and neuroprosthetics. Topics include clinical trials, combining therapies, regulatory challenges, and the importance of rehabilitation in conjunction with therapeutic technologies. 00:00 Introduction to the Neural Implant Podcast 00:16 Meet David McMillan: Director of Education...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
I n this episode of the Neural Implant Podcast, host Ladan welcomes and from , an engineering services company based in Uruguay. They discuss their work in firmware, hardware, and software development for medical devices, emphasizing their specialization in wireless communications and test automation. They also explain the benefits of contract engineering, the challenges they face, and highlight an exciting project involving an injectable neurostimulator. The conversation covers the history of neurotechnology development in Uruguay, the process and dynamics of working with clients, and...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Today's guest is from Blackrock Microsystems. While we've featured Blackrock guests before, Stephen's appearance today is driven by his podcast, , where neurotech-inspired movies are reviewed and discussed. Top 3 Takeaways: "Our goal for the podcast isn't necessarily to be overly technical, requiring a neuroscience degree to understand. We're often deep in the subject matter and may get a bit jargony, but broadly, we aim to be accessible without pretending to be accomplished neuroscience researchers." “Due to the subject's nature, movies dealing with neuroscience themes...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
is a University of Michigan PhD graduate working on thin film neural implants but has since transitioned into the legal side of things having passed his bar exam and working with . This interview took almost 2 years to get done but we're glad we were able to do it! Top 3 Takeaways: "I think the main thing I'll say is you don't undermine your valuation by not having an informed and intentional patent strategy, and you don't have to go cheap. You know, I feel that you have to bootstrap, but if you work with certain law firms that are very entrepreneurial friendly, and my...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
"Welcome to today's episode! Our guest, , co-founder and CEO of , brings innovation to neural implants. With roots in France and a Harvard PhD, he's leading groundbreaking work. Welcome, Paul!" Top 3 Takeaways: "It's a good time to ask the question: What if we could develop solutions tailored for this problem instead of borrowing from the semiconductor industry? That's what Axsoft is about. We emphasize developing soft materials that offer better long-term biocompatibility. Additionally, these materials are suitable for micro and nano fabrication and remain stable inside the...
info_outlineNeural Implant podcast - the people behind Brain-Machine Interface revolutions
Today’s guest is who is a share who works in regenerative neural tissue engineering. Top 3 Takeaways: "We're trying to create scaffolds that can be templates for the body to repair itself, to grow around, and ultimately become natural tissue, seamlessly integrating with the body's own." "Other faculty were discouraging. This is because academia tends to prioritize scholarly pursuits such as papers and grants, often undervaluing applied work and its real-world applications." "Our clinical collaborator actively participated in the lab alongside Sarah. Together, they would work on...
info_outlineDan Brounstein is Chief Strategy Officer at Saluda Medical where he is using his 15 years of Spinal Chord Stimulator experience to help deliver closed-loop pain relief directly to the spinal cord.
***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services here***
Top 3 Takeaways:
- "We're stimulating with milliamps and we're trying to measure in microvolts, and we always use the analogy trying to listen to a pin drop next to a shotgun shot"
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"There's a lot of literature on loss of efficacy? It's just a therapy issue. When you deliver open-loop therapies blind across a neural target, you're ultimately going to create, over-stimulation in a lot of times under stimulation. On top of that, over time things change"
- "Patients come in between four and five times a year on average in perpetuity with open loop systems"
0:45 " Do you want to introduce yourself and the company better than I just did?"
6:00 "Your guys' device reprograms on its own? And then what signals does it take in and how does it change the stimulation patterns based on that?"
9:00 Iris Biomedical ad sponsorship
9:45 "What is your input and output for your guys' device?"
11:45 "In February of 2023, you guys got FDA approval for this. Do you wanna talk a little bit about this?"
14:15 "Is it like 5% better than open loop or is that something that's gonna be coming out published later?"
17:00 "Is there another indication?"
18:15 "The last I guess seven years for you has been very exciting. Is there anything on the horizon for the next seven years?"
20:15 "You guys have 300 people and have raised 200 million. What's it like working in such a big company"
22:45 "Is it getting too big for you?"
23:45 "What advice do you have for people in your situation?"
26:00 "Is there anything that we didn't talk about that you wanted to mention?"