loader from loading.io

Lothar Krinke on adaptive Deep Brain Stimulation at Newronika

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Release Date: 12/10/2022

Exploring Contract Engineering in Neurotechnology with Javier Shandy and Nicolas Barabino show art Exploring Contract Engineering in Neurotechnology with Javier Shandy and Nicolas Barabino

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

I n this episode of the Neural Implant Podcast, host Ladan welcomes and from , an engineering services company based in Uruguay. They discuss their work in firmware, hardware, and software development for medical devices, emphasizing their specialization in wireless communications and test automation.  They also explain the benefits of contract engineering, the challenges they face, and highlight an exciting project involving an injectable neurostimulator. The conversation covers the history of neurotechnology development in Uruguay, the process and dynamics of working with clients, and...

info_outline
Stephen Ho: Exploring Neurotech in Cinema with the Neurratives Podcast show art Stephen Ho: Exploring Neurotech in Cinema with the Neurratives Podcast

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Today's guest is from Blackrock Microsystems. While we've featured Blackrock guests before, Stephen's appearance today is driven by his podcast, , where neurotech-inspired movies are reviewed and discussed.     Top 3 Takeaways: "Our goal for the podcast isn't necessarily to be overly technical, requiring a neuroscience degree to understand. We're often deep in the subject matter and may get a bit jargony, but broadly, we aim to be accessible without pretending to be accomplished neuroscience researchers." “Due to the subject's nature, movies dealing with neuroscience themes...

info_outline
Eugene Daneshvar: Navigating Neurotech and Patents show art Eugene Daneshvar: Navigating Neurotech and Patents

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a University of Michigan PhD graduate working on thin film neural implants but has since transitioned into the legal side of things having passed his bar exam and working with . This interview took almost 2 years to get done but we're glad we were able to do it!     Top 3 Takeaways: "I think the main thing I'll say is you don't undermine your valuation by not having an informed and intentional patent strategy, and you don't have to go cheap. You know, I feel that you have to bootstrap, but if you work with certain law firms that are very entrepreneurial friendly, and my...

info_outline
Paul Le Floch: Pioneering Neural Implant Materials with Axoft show art Paul Le Floch: Pioneering Neural Implant Materials with Axoft

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

 "Welcome to today's episode! Our guest, , co-founder and CEO of , brings innovation to neural implants. With roots in France and a Harvard PhD, he's leading groundbreaking work. Welcome, Paul!"  Top 3 Takeaways: "It's a good time to ask the question: What if we could develop solutions tailored for this problem instead of borrowing from the semiconductor industry? That's what Axsoft is about. We emphasize developing soft materials that offer better long-term biocompatibility. Additionally, these materials are suitable for micro and nano fabrication and remain stable inside the...

info_outline
Christine Schmidt: Pioneering Regenerative Neural Tissue Engineering show art Christine Schmidt: Pioneering Regenerative Neural Tissue Engineering

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Today’s guest is who is a share who works in regenerative neural tissue engineering. Top 3 Takeaways: "We're trying to create scaffolds that can be templates for the body to repair itself, to grow around, and ultimately become natural tissue, seamlessly integrating with the body's own." "Other faculty were discouraging. This is because academia tends to prioritize scholarly pursuits such as papers and grants, often undervaluing applied work and its real-world applications."  "Our clinical collaborator actively participated in the lab alongside Sarah. Together, they would work on...

info_outline
Bioel 2024 Conference panel with Drs Jon Viventi, Tracy Cui, Ellis Meng, and Ivan Minev show art Bioel 2024 Conference panel with Drs Jon Viventi, Tracy Cui, Ellis Meng, and Ivan Minev

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

Welcome to the Neural Implant Podcast! In this episode, the podcast team presents a live panel recording from the Bio L Conference at the International Winter School on Bioelectronics in Austria in March 2024. Hosted by Ladan, the panel discusses various types of neural implants with esteemed guests: Drs . (LCP neural implants), (PEDOT electrode coatings), (parylene neural implants), and (PDMS neural implants). Tune in as they explore the fascinating world of soft implantable electrodes and brain-nervous system interfaces.   Top 3 Takeaways: “In the next five or 10 years, I...

info_outline
Carles Garcia-Vitoria: Pioneering Pain Relief with Intrathecal Spinal Cord Stimulation with Spinally show art Carles Garcia-Vitoria: Pioneering Pain Relief with Intrathecal Spinal Cord Stimulation with Spinally

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

In today's episode, we're joined by , a seasoned pain physician with a unique approach to his work. With extensive experience in regional anesthesia and pain management, Carles shares insights gained from his years of practical experience as he pursues his PhD in Spain.  Top 3 Takeaways: "We believe we have the opportunity to target the site of action more effectively. That's why we've founded Spinally, the startup we're currently leading. Our goal is to pioneer intrathecal spinal cord stimulation." "The Dura Mater is highly elastic, closing approximately 80-90% within the first 30...

info_outline
Steve Goetz: Revolutionizing Mental Health Treatment as CTO of Motif Neurotech show art Steve Goetz: Revolutionizing Mental Health Treatment as CTO of Motif Neurotech

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is now the Chief Technology Officer at which is developing a minimally invasive neural implant for the treatment of depression and mental health issues. Steve was at Medtronic for 26 years before moving over to the startup landscape. Top 3 Takeaways:  "Starting a big program that you don't know how to finish is a very expensive endeavor, and so you want to really shake out all the science risk, all the technology risk,  be pretty sure you can execute a thing before you turn on that big engine because it's expensive once you go" "We know stimulation of the dorsal lateral...

info_outline
Eric Glowacki on cutting edge neural implant fabrication show art Eric Glowacki on cutting edge neural implant fabrication

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is a research group leader at the Central European Institute of Technology () located in Brno, Czech Republic. There he studies neural implant fabrication and materials specializing in silicon, parylene, and polyimide devices. He has also started to designs and fabricate devices on a contract basis for other research groups and companies. And, his institute is the one that has been recently sponsoring the podcast! This podcast is sponsored by CEITEC Nano, check out their Neurotech Device Manufacturing Capabilities  Top 3 Takeaways: "You can just buy stuff on the internet very simple red...

info_outline
Gene Fridman on his freeform stimulator allowing for more neural stimulation possibilities show art Gene Fridman on his freeform stimulator allowing for more neural stimulation possibilities

Neural Implant podcast - the people behind Brain-Machine Interface revolutions

is an Associate Professor in the Department of Otolaryngology Head and Neck Surgery and also has appointments with the Department of Biomedical Engineering and the Department of Electrical and Computer Engineering. His research is in the areas of bioinstrumentation and neural engineering. In this episode we talk about his freeform nerual stimulator which allows for DC and any other waveforms without any electrolytic effects on the electrodes. This opens up many possibilities for neural stimulation. We also talk about his startup Aidar which is like a 'tricorder' all-in-one medical diagnostic...

info_outline
 
More Episodes

Lothar Krinke is the CEO and Board Member of Newronika which is an adaptive Deep Brain Stimulator company looking to improve patient outcomes in things like Parkinson's and Essential Tremor.

***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services here***

Top 3 Takeaways:

  • "the one thing we do need to address is really the cost. The cost driver of Deep Brain Stimulation isn't the manufacturing of the system. Now, that's not cheap either it's certainly less than $10,000. How expensive is brain surgery, particularly functional brain surgery? How expensive is it to have all the pre-operation preparation? So I think the field needs to think about how we can lower the cost of Deep Brain Stimulation to make it available to not hundreds of thousands of patients, but literally millions of patients."
  • "I don't think AI or even machine learning has been sufficiently applied in our space. People do it and they talk about it, but if you look at other fields, even EEG, use of AI or machine learning are much more penetrated."
  • "In my mind it is almost unconscionable that only 15% of patients that could benefit from Parkinsons, from DBS do. So somehow we need to have a battle cry. We need to have the responsibility to make this therapy available to more people. And the way to do that is less invasive more automation and lower cost"

0:45 Do you want to introduce yourself better than I just did?

2:15 "Why is Deep Brain Simulation so exciting for you?"

3:15 "Can explain what Deep Brain Stimulation is and what it's a treatment for?"

5:30 "How did you get into the field?"

6:30 Iris Biomedical ad sponsorship

7:15 You thought earlier that DBS was too invasive but now changed your mind, why?

8:15 What are the biggest impediments to DBS?

12:15 Why is the Newronika DBS better than the alternatives?

14:30 Why is adaptive DBS better?

16:30 "What are some of the biggest challenges right now at Newronika?"

20:30 You are in Minneapolis, West Virginia, and Milan, how are you able to travel so much?

21:30 "Why aren't you in Gainesville? I was surprised how big the DBS field is here."

22:15 "For people starting out in the field, do you have any advice?"

25:30 " What's a big mistake or wrong direction that you see researchers or people on your field going down?"

27:45 "Could you explain the beta and gamma waves?"

32:45 "Is there anything that we didn't talk about that you wanted to mention?"