Expert comment: AMG 510 KRAS inhibitor trial results – ‘A good start’ (with Colin Lindsay)
Release Date: 10/07/2019
Medicine Matters oncology
We speak to medical oncologist Narjust Duma, from the University of Wisconsin in the USA, about COVID-19 vaccination in people with cancer, discussing issues such as vaccine timing, side-effects, and key unanswered research questions.
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In this Medicine Matters oncology podcast, we speak to Gary Lyman (Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, USA) about the impact of the COVID-19 outbreak on the conduct of cancer clinical trials.
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Co-project leader Lennard Lee talks about the inception and development of the initiative that will provide insight into the impact of COVID-19 on people with cancer and facilitate shared learning that will benefit patient care.
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Gilberto Lopes (Sylvester Comprehensive Cancer Center at the University of Miami, Florida, USA), a steering committee member of CCC19, tells us about the registry collating data on cancer patients with comorbid COVID-19 to provide an evidence base for future decision-making.
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Thoracic oncology nurse practitioner Beth Sandy explains how the coronavirus pandemic is affecting cancer patient care and how strategies such as telemedicine are coming into their own.
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Genitourinary oncologists Cora Sternberg (Weill Cornell Medicine, New York, USA) and Axel Merseburger (University Hospital Schleswig-Holstein, Lübeck, Germany) share their experience of managing cancer patients during the COVID-19 pandemic, comparing perspectives from a US and German stand point.
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Gilberto Lopes discusses the impact of the COVID-19 pandemic on the management of patients with lung cancer and outlines the measures being implemented to minimize the risk for patients.
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Colin Lindsay discusses the trial results for AMG 510 – a novel inhibitor targeting the KRAS G12C mutation – in patients with locally advanced or metastatic non-small-cell lung cancer.
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Recent research has shown an association between intestinal microbiota and response to immunotherapy in the setting of various tumor types. Listen to Jennifer Wargo, from The University of Texas MD Anderson Cancer Center in Houston, USA, share her insights into the findings.
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Hashim Ahmed takes us through the COMPARE study which showed that men with localized prostate cancer are willing to accept lower survival odds for a better quality of life. He outlines the key findings, the implications of the results for physicians, and the next steps for research.
info_outlineColin Lindsay discusses the trial results for AMG 510 – a novel inhibitor targeting the KRAS G12C mutation – in patients with locally advanced or metastatic non-small-cell lung cancer.